The University of Kansas: Journals@KU
Not a member yet
16504 research outputs found
Sort by
EValuation of Acute and Early Phase P2Y12 Inhibitor DE-escalation After Percutaneous Intervention (EVADE PCI)
Get PDFIntroduction. Aspirin and an oral P2Y12 inhibitor are recommended for one year after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes. While ticagrelor or prasugrel are preferred over clopidogrel, de-escalation often is based on provider judgment. This study compared cardiovascular outcomes and bleeding risks between patients who remained on ticagrelor or prasugrel (unchanged group) and those de-escalated to clopidogrel within 30 days of PCI. Methods. We analyzed data from patients admitted between June 2014 and December 2022 for acute coronary syndromes requiring PCI who received an oral P2Y12 inhibitor within 72 hours of admission. The primary outcome was a composite of all-cause mortality, urgent revascularization, stent thrombosis, stroke, and major bleeding at one year. Secondary outcomes included individual components of the composite outcome. Statistical analyses included chi-square tests, Student’s t-tests, or non-parametric equivalents.Results. A total of 210 patients met the inclusion criteria, with 149 remaining on unchanged P2Y12 therapy and 61 undergoing de-escalation. There was no statistically significant difference in the composite outcome between the unchanged and de-escalated groups (n [%]: 25 [17] vs. 6 [10]; χ² [1, N = 210] = 1.658, p = 0.198). Additionally, secondary outcomes did not differ significantly between groups. Conclusions. A composite outcome of all-cause mortality, urgent revascularization, stent thrombosis, stroke, and major bleeding at one year was similar between patients who continued ticagrelor or prasugrel and those de-escalated to clopidogrel within 30 days of PCI. Larger studies are needed to confirm these findings and assess optimal timing for therapy adjustments
The Relationship between Radiation Therapy and Urinary Incontinence in Prostate Cancer Patients
Get PDF
“There was a need in the community”: Practitioners’ Motivations to Providing Mental Health Services to Forced Migrants
Get PDFMillions of individuals around the globe have been displaced from their countries due to disasters, including persecution, war, disease, famine, and weather events. Many forced migrants (FMs) experience mental health concerns that warrant treatment but often face significant barriers to care, including a limited pool of mental health practitioners (MHPs) who are competent, willing, and able to serve them. In Alaska, the Working Alongside Refugees in Mental Health (WARM) program was developed to address this need. After conducting the first WARM workshop, our team sought to understand how MHPs in Alaska are recruited and retained in working with forced migrants to further develop and maintain our program. We examined MHPs’ motivations to work with FMs through 13 qualitative semi-structured interviews with MHPs who engage in such work. Experiences with FMs and awareness of FMs in their communities, competence, and connections with other practitioners increased MHPs’ motivation and led to service delivery. Community psychology is well positioned to enhance services for FMs through both practitioner-level interventions and systemic interventions. Strategies for increasing and sustaining MHPs’ motivations to work with FMs include: forming connections with other MHPs and trusted individuals and organizations, increasing competence to work with FMs via specialized training networks, integrating experiences working with FMs into training programs, and engaging in advocacy to address systems-level barriers to care
