3372 research outputs found
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Green Synthesis of Silver Nanoparticles using Lemon Extract, Characterization, and Antimicrobial Properties
No full textA greener method of synthesizing silver nanoparticles (AgNPs) using lemon extract was investigated in this study. The synthesized AgNPs were characterized using the ultraviolet–visible (UV–Vis) spectrometer and the scanning electron microscope (SEM) machine. Both the UV–Vis spectra and SEM images indicated the presence of AgNPs and metallic silver particles. The antimicrobial properties of AgNPs were tested using the disk diffusion agar method on four different bacteria: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Vibrio parahaemolyticus; zones of inhibition were observed
Using the Ketogenic Diet to Reduce the Incidence of Pediatric Seizures: Helping Children and Families to Find a Better Quality of Life
No full textThe use of diet modifications to control seizures is showing promise as an alternative to medications in pediatric patients
Teaching Entomology Through Childrens Stories
No full textThere are very few children's books that teach them about insects. This project was designed to help children learn and understand entomology through stories. The requirements of this project was to research about an insect order and a few different families. When collecting information, primary and secondary sources were used, and a bibliography was developed to help keep a record of the sources. Information about an insect's life history, behaviors, and morphological adaptations were researched for creating this story
Indicators of Financial Crisis
No full textThe research is about analyzing some of the financial variables that can help indicate future economic crises. The studies will show why the chosen variables are suitable for the subject matter based on their reaction to past financial crisis periods
An Investigation into the Interactions between Various Amyloid-Beta Species and a Formulated Fluorescent Probe
No full textThis research investigated the fluorescence of mixtures of Aβ species and curcumin at different Aβ concentrations
Nanoformulation of Curcumin to Improve Pharmacologic Activity
No full textFound in the plant Curcuma longa (turmeric), curcumin demonstrates a diverse array of medicinal properties with antioxidant, anti-inflammatory, antimicrobial, anticancer, and neuroprotectant activities. One promising application of curcumin in the treatment and diagnosis of Alzheimer’s disease (AD) has gained scientific interest. The toxic structures, made out of amyloid-beta (Aβ) peptides aggregate in the brain tissue, can cause irreversible neuronal damage, manifesting in clinical signs associated with AD. Research has found curcumin able to bind to Aβ structures to ultimately inhibit toxic structure formation. Curcumin can also serve as a fluorescent probe to monitor the formation of senile plaques, since it interacts differently with various Aβ species. Such diagnostic and therapeutic potential can be hindered by the lack of drug delivery systems developed to ensure the efficient delivery of curcumin to the target site. Being a lipophilic(hydrophobic) substance, the low water solubility of curcumin prevents adequate drug transport in aqueous environment. One method of delivery involving nanoformulation through use of liposomes shows promise to increase curcumin’s solubility for its delivery, along with protection of loaded curcumin from premature degradation. In our research, curcumin was loaded into liposomes under different conditions. The stability of liposomes loaded with curcumin over time was investigated. Our research would assist scientists in therapeutic and remedial drug development to maximize the pharmacologic activities of curcumin
Salty Microglia: Gaining Mechanistic Insight Into Sodium-Dependent Hypertension
No full textMr. Moreira is researching the role played by the microglia (non-neuronal cells in the brain and spinal cord) in salt-sensitive hypertension
