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    Poor industry conditions as an external disciplining mechanism in takeovers

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    Search for quantum black hole production in lepton+jet final states using proton-proton collisions at √

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    A search for quantum black holes in electron+jet and muon+jet invariant mass spectra is performed with 140  fb−1 of data collected by the ATLAS detector in proton-proton collisions at

    Drop impact onto immiscible liquid films floating on pools

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    The interface dynamics of a droplet impacting onto a liquid pool has been well studied, and the common interfacial velocity quantified for the cases when the pool is both the same and a different fluid to the impacting droplet. In this work we investigate, experimentally and computationally, the scenario of a droplet impacting onto a pool of the same fluid coated by a layer of another fluid with various thicknesses. The effect of the film thickness on the penetration velocity of the upper droplet-film interface is measured for experiments and simulations, and carefully compared to theoretical predictions for early-to-moderate timescales in the limiting cases of: (i) zero film thickness, in which the film has no effect and thus behaves like a fluid on same fluid impact, and (ii) infinite film thickness, in which the underlying pool has no effect. For finite layer thickness cases we carefully quantify the transition between the two limiting scenarios, and provide insight into the interfacial and flow quantities of interest, with a robust transitional behaviour observed over a rich parametric landscape. This exploration provides new quantitative insight into the nonlinear behaviour of the multi-fluid systems in newly explored finite thickness regimes, as well as a clear delineation of their effect in the context of the noted distinguished limits, with films of up to one impacting drop diameter in thickness shown to induce meaningful interpretable changes in the resulting post-impact dynamics. We also explore longer timescale features of the lower interface dynamics, revealing comparatively lower velocities and larger film thicknesses as the liquid film viscosity is increased

    Evaluating computed bony range of motion (BROM) by registering in-vitro cadaver-based functional range of motion (FROM) to a hip motion simulation

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    While modern hip replacement planning relies on hip motion simulation (HMS), it lacks the capability to include soft-tissues and ligaments restraints on computed bony range of motion (BROM), often leading to an overestimation of the in-vivo functional range of motion (FROM). Furthermore, there is a lack of literature on BROM assessment in relation to FROM. Therefore, the study aimed to assess computed BROM using in-vitro cadaver-derived FROM measurements, registered to a CT-based in-house HMS, and to further investigate the effect of functional and anatomical hip joint centres (FHJC and AHJC) on BROM. Seven limiting and three non-limiting circumducted passive FROM of four cadaver hips were measured using optical coordinate measuring machine with reference spheres (RSs) affixed to the pelvis and the femur, following CT-scan of the specimen. The RSs' centres were used to register the measured FROM in HMS, enabling its virtual recreation to compute corresponding BROM by detecting nearest bony impingement. FHJC, estimated from non-limiting FROM, was compared with AHJC to examine their positional differences and effect on BROM. Differences in BROM and FROM were minimal in deep flexion (3.0° ± 4.1°) and maximum internal rotation (IR) at deep flexion (3.0° ± 2.9°), but substantially greater in extension (53.2° ± 9.5°). Bony impingement was observed during flexion, and IR at deep flexion for two hips. The average positional difference between FHJC and AHJC was 3.1 ± 1.2 mm, resulting in BROM differences of 1°-13° across four motions. The study provided greater insight into the applicability and reliability of computed BROM in pre-surgical planning

    Bayesian and frequentist approaches to rescuing disrupted trials : a report from the NISS Ingram Olkin Forum Series on unplanned clinical trial disruptions

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    The COVID-19 pandemic impacted clinical trials in ways never expected. However, similar challenges should now be expected going forward. These challenges made us aware of statistical problems arising from other types of disruptions that had not previously captured the attention of the statistical community. This article describes some frequentist and Bayesian statistical tools that can be used with future disruptions and illuminates issues that could benefit from more statistical research. Disruptions may threaten a clinical trial’s validity. Here, we address two resultant challenges: (a) performing an unplanned analysis with options to stop and/or change the sample size; and (b) changes in the study population that are observable or unobservable at the patient level. Different paradigms lead to different ways of doing things, but many statisticians work exclusively within a Bayesian or frequentist paradigm. We propose and provide side-by-side descriptions of Bayesian and frequentist approaches to dealing with these challenges. An illustrative phase III trial aims to compare second-line therapies for type 2 diabetes. We compare and contrast Bayesian and frequentist coping strategies assuming the trial was interrupted due to COVID-19, focusing on Type I error control and the expected loss from a specific utility function

    Statistical analysis of magnetic divertor configuration influence on H-mode transitions

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    DIII-D plasmas are compared for two upper divertor configurations: with the outer strike point on the small angle slot (SAS) divertor target and with the outer strike point on the horizontal divertor target (HT). Scanning the vertical distance between the magnetic null point and the divertor target over a range 0.10–0.16 m is shown to increase the threshold power, Pth , and edge plasma power, PLoss , for the low-to-high confinement (L–H) and H–L transitions respectively, by up to a factor of 1.4. The X-point height scans were performed at three L-mode core plasma line average electron densities, n¯e= 1.2, 2.2 and 3.6 ×1019m−3 , to investigate the density dependence of divertor magnetic configuration influence on Pth . The X-point height, Zx-pt , was further extended across the range 0.16–0.22 m with the more open HT divertor configuration, for which a clear decrease in Pth with increasing Zx-pt is observed. The dependence of Pth on divertor magnetic geometry is further investigated using a time-dependent probability density function (PDF) model and information geometry to elucidate the roles played by pedestal plasma turbulence and perpendicular velocity flows. The degree of stochasticity of the plasma turbulence is observed to be sensitive to the plasma heating rate. The calculated square of the information rate shows changes in the relative density fluctuations and perpendicular velocity PDFs begin 2–5 ms prior to the L–H transition for three plasmas; providing a crucial measurement of the dynamic timescale of external transport barrier formation. Additionally, both information length and rate provide potential predictors of the L–H transition for these plasmas

    Jesus calling the first disciples : reading Luke’s account through the lenses of sensing and intuition

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    The Lucan account of Jesus’ calling of the first disciples differs from the dominant and better known Marcan narrative in a number of ways. The Lucan account has been prefaced by an introduction to the person and actions of Jesus and specifically triggered by the miraculous catch of fish that Luke shares with John 21. Drawing on psychological type theory and the SIFT approach to biblical hermeneutics, this study tests the hypothesis that sensing types and intuitive types will see different things in this passage. The theory was tested by inviting a group of 19 clergy and lay members of ministry teams to work in type-alike groups. The data are consistent with the theory

    Sharp asymptotic estimates for expectations, probabilities, and mean first passage times in stochastic systems with small noise

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    Freidlin-Wentzell theory of large deviations can be used to compute the likelihood of extreme or rare events in stochastic dynamical systems via the solution of an optimization problem. The approach gives exponential estimates that often need to be refined via calculation of a prefactor. Here it is shown how to perform these computations in practice. Specifically, sharp asymptotic estimates are derived for expectations, probabilities, and mean first passage times in a form that is geared towards numerical purposes: they require solving well-posed matrix Riccati equations involving the minimizer of the Freidlin-Wentzell action as input, either forward or backward in time with appropriate initial or final conditions tailored to the estimate at hand. The usefulness of our approach is illustrated on several examples. In particular, invariant measure probabilities and mean first passage times are calculated in models involving stochastic partial differential equations of reaction-advection-diffusion type

    Effects of delayed testing on decisions to stop learning

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    This study explores whether people’s preference to restrict to-be-learned material is influenced by memory test timing. In Experiments 1a and 2a, participants studied word lists. For control groups, lists were displayed in their entirety, whereas participants in other groups could stop the lists early. We investigated whether participants decided to terminate learning when they expected their free-recall memory to be tested after a short (Experiment 1a) or long (Experiment 2a) delay. Experiments 1b and 2b tested participants’ theoretical assumptions about learning termination. Participants who terminated learning recalled fewer words than those who saw all to-be-remembered materials. When the memory test immediately followed the learning phase, more than half of the participants decided to stop learning. However, when there was any time delay between learning and testing, only around a quarter of them decided to stop. Delayed testing can effectively discourage a maladaptive learning strategy of learning termination

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