Kufa Journals System University of Kufa
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Tracking of Ceotaneous Leishmaniasis by Parasitological, Molecular and Biochemical Analysis
Abstract:Background: In areas of endemicity without sufficient laboratory infrastructure, identification of Leishmaniaparasites is useful for control and preventive plan and very important since species differentiation is instrumental in selection of optimal therapy and treatment regimens.Aim: The present study was performed to identify the species and strain of Leishmaniaparasiteisolated from different endemic areas .Materials and Methods: In a consecutive series of 104 patients referred for a suspected CL lesion during October 0212 to December 0210 in five Iraqi provinces, direct smear and culture followed by molecular and biochemical analysis were done using nested-PCR and cellulose acetate electrophoresis
Hemodynamic Changes During Spinal Anesthesia For Elective Cesarean Section With Hyperbaric Bupivacaine: Effect Of Volume And Concentration
AbstractBackground: Spinal anesthesia for cesarean section with hyperbaric Bupivacaine is widely used. The course of the procedure is frequently troubled by hemodynamic instability that is determined by the level of spinal block and this in turn depends on the spread of the local anesthetic within the CSF. By fixing the dose of the local anesthetic any increase in its volume leads to a decrease in its concentration because these factors are closely related to each other and they can affect the spread of the local anesthetic.Objective: To compare between large volume but lower concentration (4 ml of 0.25%) and small volume but higher concentration (2 ml of 0.5% ) of hyperbaric Bupivacaine solutions used for spinal anesthesia for elective cesarean section in respect to hemodynamic changes.Method: A clinical interventional study was Performed at Al-Zahra'a Teaching Hospital (Najaf ) from 18th Jun.-18th Jul. 2013. Forty patients scheduled for elective cesarean section were randomly selected and randomly divided into two equal groups (A and B). Both groups received hyperbaric Bupivacaine via intrathecal route, group (A) received 4 ml of 0.25% solution while group (B) received 2 ml of 0.5% solution. Hemodynamic variables (blood pressure and heart rate) were recorded throughout the time of anesthesia. Data was analyzed by using SPSS version 20.Results: There was no significant difference in the incidence of hypotension (P value=1.0) between the two groups while the incidence of bradycardia was equal between the two groups (10%) but there was a need for significantly higher average dose of Ephedrine that was used to treat hypotension in group (A) than in group (B) (P value=0.49%) reflecting more severe hypotension in group (A) than group (B).Conclusion: we conclude that the volume factor has more influence than the concentration on blood pressure with regard to hyperbaric intrathecal Bupivacaine solutions used for elective cesarean section.Recommendation: the use of smaller volume but higher concentration of intrathecal Bupivacaine is advisable in elective cesarean section.Keywords: Spinal anesthesia, Cesarean section, Hyperbaric Bupivacaine
Effect of rapid freezing and thawing on Malondialdehyde concentration , abnormal sperm chromatin percent and sperm parameters of Asthenozoospermic patients
Abstract :Objective : The study aimed to study the effect of rapid freezing and thawing on Malondialdehyde concentration andabnormal sperm chromatin percent and sperm parameters of Asthenozoospermic patientsMethodology : This study was performed in the laboratory of Intra cytoplasmic Injection and freezing of sperm in thefertility center of Al-Sader Medical City / Al-najaf Alashraf City during the period from May, 2012 to April 2013 ,The study included 30 of Asthenozoospermic patients, the statistical analysis of this study performed by usingStudent's t – test and paired t – test at the level of probability 0.05Results : the results showed that is sperm rapid freezing process of patients who were Included in the study by usedsperm freezing media ( Sperm Freeze) and doing the thawing processes after one month From freezing leads to asignificant decreasing (p<0.05) In the sperm concentration, sperm progressive motility percent, sperm viabilitypercent and normal sperm morphology percent. and a significant increasing (p<0.05) In The Malondialdehydeconcentration and abnormal Sperm chromatin percent and no significant difference(p<0.05) In round Cellconcentration in comparison with their ranges after activationConclusion : It can be concluded From this study that sperm rapid freezing and thawing processes had a negativeeffects on the semen and sperm parameters and Malondialdehyde concentration and abnormal sperm chromatinpercent In the all samples of study included patients .Recommendation: Adding Anti oxidants to the sperm freezing media to decrease the negative effects of freezingand increase the sperm parameters .Keyword : effect , rapid freezing, thawing, Malondialdehyde, chromatin, sperm parameters , Asthenozoospermi
Using Multiplex PCR Assay for Detection of Genital Mycoplasmasand Ureaplasmaspp in an Infertility Males.
ABSTACTThe result of the multiplex-PCR revealed positive results in 13(15.1%) of the 86 seminal fluid samples from infertile patients which represented M.hominis 5(5.8%), U.urealyticum in 5(5.8%) and U.parvum3(3.5%).Conclusion: in light of the results obtained this study we concludes that the efficiency of multiplex-PCR large and rapid in diagnosis of Ureaplasmaspp and Mycoplasma hominis in seminal fluid.Recommendation : the study of detection of other microorganism (viruses, fungi, Chlamydia and Neisseria gonorrhea) in men infertility.Key words: Multiplex-PCR,Mycoplasma, Ureaplasma,Men, Infertility
Assessment of Patients’ Adherence to Therapeutic Recommendations after Ischemic Heart Diseases in Al-Najaf City
ABSTRACTBackground: Cardiovascular diseases (CVD) continue to become a global health problem, and affect a millions of people worldwide. Also the cardiovascular diseases affect people at all ages and it's not just a disease of elderly. Objectives To assess of patients adherence to therapeutic recommendations after ischemic heart diseases. And to find out the association between the patients’ demographic and clinical data and their adherence to therapeutic recommendations. Methodology descriptive Study is carried out in Al-Najaf Health Directorate / Al-Sadder Medical City/ Al-Najaf Center for Heart Diseases and Surgery, from June, 5th, 2013 to April, 10th, 2014. A non-probability (purposive sample) of (102) patients with ischemic heart diseases (angina and myocardial infarction), were included in the study. The data are collected through the use of a questionnaire, which consists of three parts one includes Socio-demographic and clinical data form, part two, includes patients adherence to therapeutic recommendations form. The data were described statistically and analyzed through use of the descriptive and inferential statistical analysis approaches. Results The study results show that the patients with ischemic heart diseases are fairly adhere to therapeutic recommendations. And there is a significant relationship of the residency, gender, and the patients occupational status on their adherence to therapeutic recommendations.Conclusion, There is a deficient in the patients' adherence to therapeutic recommendations.Recommendations, An intensive comprehensive studies could be conducted to assess the patients adherence to therapeutic recommendations and the factors that may affect such adherence, with a suitable solutions for these factors to improve the level of patients adherence.Key wards: assessment, patients adherence, ischemic heart disease
The Theoretical Model of Interaction of the Hydrocortisone (anti-inflammatory drug) with Carbon Nanotubes (as delivery)
The aim of this article is to examine the possibility of using carbon nanotubes as delivery for Hydrocortisone drug. We have performed the modeling of the quantum interaction properties of hydrocortisone radicals on the single walled carbon nanotubes surface. It is investigated by PM3 (parameterized model number 3) calculations. The effect of three factors which are the diameter, length, and position characteristics of the CNT on binding hydrocortisone have been studied . The results showed that with increasing the diameter of CNT diameter, the binding energy decreases while as the CNT length increases the binding energy increases smoothly and then some fluctuations were appeared as a result of the steric effects. The results of changing the binding positions of hydrocortisone with CNT proved that the complex formed by the hydrocortisone radical on the single-tube wall is more stable when the reaction occurs in the middle of the CNT. According to the results the CNT can be suitable delivery for the hydrocortisone drug
تأثير الحامضين العضويين الدباليين الهيوميك و الفولفيك و نوعية مياه الري في بعض مؤشرات النمو الخضري لأشجار نخيل التمر Phoenix dactylifera L.) ) الفتية صنف برحي
نفذ البحث في بستان محطة النخيل النسيجية / وزارة الزراعة الكائنة في المنطقة الصحراوية لمحافظة النجف الأشرف خلال العامين 2013 و 2014 على ستين شجرة فتية بعمر ثلاث سنوات من نخيل التمر( صنف برحي ) لغرض دراسة تأثير إضافة الأحماض العضوية الدبالية في تحسين النمو الخضري للنخلة النامية في المناطق الصحراوية و دورها في إحداث التغييرات في بعض الصفات المظهرية والتشريحية للأوراق حيث استعملت عشر معاملات بتراكيز مختلفة من الحامضين العضويين ( الهيوميك والفولفيك ) وذلك بإضافة محاليلها إلى التربة حول النخلة أو رشها على الأوراق شهريا ولفترة ستة عشر شهرا متتاليا اعتبارا من 6 / 2 / 2013 مع استعمال نوعين من مياه الري ( ماء بئر أو ماء نهر الفرات ) , أجريت قياسات نتائج الصفات المدروسة في ثلاثة مواعيد و هي 1 /6 / 2013 و 1 /11 /2013 و 1 / 6 /2014 , أظهرت النتائج بأن معاملات الأحماض العضوية سببت حصول زيادة معنوية في معدلات عدد الأوراق و طول الورقة و طول الوريقة وخفض معنوي في سمك طبقة الكيوتكل في الأوراق عند موعدي القياس الثاني و الثالث و قد تفوقت في معاملات حامض الهيوميك 12 % ( 15 مل.لتر-1) أو حامض الهيوميك 80 % ( 6 غم .لتر-1) إضافة أرضية أو حامض هيوميك 18 % + حامض فولفيك 3 % ( 6 أو 9 مل .لتر-1) رشاً ورقياً , كما أظهرت النتائج بأن استعمال ماء البئر سبب خفض معنوي في معدلات عدد الأوراق و طول الورقة و طول الوريقة و زيادة معنوية في سمك طبقة الكيوتكل و قد حصل العكس عند استعمال ماء النهر , أما التداخل بين عاملي الدراسة فقد سبب تأثيرات معنوية في الصفات المدروسة ظهر أغلبها في موعدي القياس الثاني و الثالث و قد تفوقت معدلاتها في معاملات حامض الهيوميك 12 % (15 مل.لتر-1) أو حامض الهيوميك 80 % ( 6 غم.لتر-1) إضافة أرضية أو حامض هيوميك 18 % + حامض فولفيك 3 % ( 6 أو 9 مل.لتر-1) رشاً ورقياً إذ سببت زيادة معنوية في معدلات عدد الأوراق و طول الورقة و طول الوريقة و خفض معنوي في سمك طبقة الكيوتكل .كلمات مفتاحيه : نخلة التمر Phoenix dactylifera L.) ). الأحماض العضوية الدبالية . الإجهاد الملحي . التغذية الورقية
Comparative study among aqueous, hexane extracts of sweet almond (Prunusamygdalus) with Atorvastatin for treating hyperlipidemia induced in mice
This research was developed to find out the treatment impact of aqueous and hexane extracts of sweet almond (Prunusamygdalus) on some biological indicators related to hyperlipidemia that induced inmiceand comparative with Atorvastatin which was dried and grinded by an electrical grinder to form fine crude powderthat extracted by two ways:by using 95% hexaneandwaterby using thedistilledwater with Soxhlet apparatus, (40) of mature mice were randomly separated into 8 categories (5 mouse per group) and treated every day for 60 days, the first group was fed and drank normally and regarded as a negative control group (NC1), a second group was given polypropylene glycol offered as negative control group (NC2), third group was given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia and offered as positive control group (PC), hyperlipidemia was induced in the other five categories as in the third group. Treated hyperlipidemia by hexane extract at a dose of 500 mg/ kg of body weight and aqueous extract of sweet almond with three different doses (500, 750 and 1000) mg/ kg of bodyweight and compared with the other groups that treated with atorvastatin (Lipitor) ® 20 mg/ kg B.W. as antihyperlipidemic drug. The outcomes discovered that oral dosing with extracts of sweet almond and medication therapy led to acquire beneficial changes in the parameters, which were showed incident of a significant decrease (P<0.05) at a concentration of malondialdehyde (MDA), total cholesterol (TC), triacylglycerol (TAG), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C) and atherogenic index (AI) in serum, moreover to a significant improved (P<0.05) in the concentration of high density lipoprotein cholesterol (HDL-C) and serum reduced glutathione (GSH) comparedwithuntreated group and has been proven that a dose of 1000 mg/kg of aqueous extracts of sweet almond was the best in therapy
تحليل المتغيرات المؤثرة في الاصابة بمرض سرطان الثدي والرئة في محافظات الفرات الاوسط*
لقد تبين من خلال البحث في المؤثرات الطبيعية والبشرية(درجة التحضر) والاجتماعية (الزواج , التدخين) والفسيولوجية (العمر) انها ذات تاثير كبير في الاصابة بسرطان الثدي للاناث وقد تم اختيار اربعة مؤثرات رئيسة في معدلات الاصابة هنا ولها التاثير الاكبر ( درجة التحضر , معدل العمر , الرضاعة غير الطبيعية , الزواج , المياه المعقمة ) وان درجة التحضر ومعدل العمر والزواج هي اسباب مسيطرة بنسبة كبيرة على مسببات الامراض السرطانية ومنها سرطان الثدي للاناث , اما المؤثرات الرئيسة في معدلات الاصابة بسرطان الرئة للذكور فهي( درجة التحضر , معدل العمر , التدخين , المستوى الاقتصادي , المياه المعقمة ) فان درجة التحضر ومعدل العمر والتدخين هي اسباب تاتي بالمرتبة الاولى للاصابة بسرطان الرئة للذكور في منطقة الدراس
La Modernité et les Petits Poèmes en Prose de Baudelaire
Petits Poèmes en prose or Le Spleen de Paris’ has illustratedBaudelaire’sproject for adoptingpoetryrepresents modern life. This volume depicts the life and destiny of the man in the multitude of the physical life. It is a unique thing; it represents a miracle that combines prose with poetry. In the volume of ‘PetitsPoèmes en prose or Le Spleen de Paris’, Baudelaire pays great attention to the metaphoric image and all kinds of metaphors that can reveal multiple meanings; hence, ‘PetitsPoèmes en prose’ suggests its poetry. For Baudelaire, the image is charged with symbolic payload inviting the reader to make the effort in discovering the potential secret and meaning beyond words. Baudelaire is keen on the suggestive magic in this new literary of genre; consequently, he is considered as its first pioneer. He introduces a different and new style in a special way. From contacts with big cities and countless intersected relations, this example of urgent poetry has been initiated to be suitable for describing modern life, more abstract and freedom, to be musical without rhythm or rhyme, and smooth enough to agree with the lyrical movements of the soul and the daydream ripples and awareness uprisings