JOS - UNSOED (Jurnal Online Soedirman - Universitas Jenderal Soedirman)
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CASE STUDY: THE EFFECTIVENESS OF ANKLE PUMP EXERCISE AND WARM COMPRESSES IN REDUCING THE DEGREE OF LEG OEDEMA IN PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD)
Introduction: One of the most common clinical manifestations in CKD patients is leg oedema. Oedema that is not treated promptly leads to several complications such as ischaemia due to reduced tissue function, reduced mobility, skin infections such as cellulitis or ulcers in chronic oedema. Oedema can be managed with non-pharmacological therapies such as a combination of ankle pumping and warm compresses. Purpose: This study aims to describe the reduction in the degree of leg oedema in patients with CKD after administration of ankle pump exercise and warm compresses. Methods: This research is a case study with a nursing approach to CKD patients with oedema. Participants in this study were 3 CKD patients with leg oedema. Interventions were carried out on 3 consecutive days within 15-20 minutes of each session. Pre- and post-measurements of the degree of oedema were made at each session. Discussion: Oedema is a condition resulting from an increase in hydrostatic pressure in the blood vessels, which causes the veins to become blocked and plasma fluid to accumulate in the interstitial spaces. The results of the measurement of the degree of oedema showed that two participants experienced a decrease in the degree of oedema from degree 3 to 2 and one participant experienced a decrease from degree 2 to 1. Conclusion: A combination of ankle pump exercise and warm compresses can reduce the degree of leg oedema in patients with CKD and can be used independently by patients and families
CLASSROOM-BASED PANCASILA CHARACTER EDUCATION FOR SUSTAINABLE DEVELOPMENT IN RURAL TROPICAL PRIMARY SCHOOLS
This study aims to explore the implementation of classroom-based Pancasila character education in rural primary schools as a strategic approach to sustainable human development in tropical communities. A qualitative descriptive method was used, with data collected through classroom observations, in-depth interviews with teachers and principals, and document analysis of lesson plans and character education materials. Data were analyzed manually through thematic coding using data reduction, data display, and conclusion drawing techniques. The findings show that classroom-based character education practices are contextually integrated with local wisdom and community culture. Pancasila values such as mutual cooperation, nationalism, and religious tolerance are applied through storytelling, collaborative projects, and reflective dialogues. Despite limited infrastructure and resources, schools demonstrate innovative approaches in fostering students’ moral and civic competencies. This study contributes to the fields of education and sustainable development by emphasizing the importance of contextual character education in shaping responsible, community-oriented individuals. The integration of national ideology with locally grounded pedagogical strategies proves effective in supporting character development and social sustainability in rural tropical areas
Modulatory Effect of Guava Leaf Extract on Liver Tissue in Hypercholesterolemic Rats (Rattus norvegicus)
Background: Hypercholesterolemia is a global health issue with high prevalence, contributing to conditions such as Non-Alcoholic Fatty Liver Disease (NAFLD) & Non-Alcoholic Steatohepatitis (NASH). Conventional therapies, although effective, have side effects. Guava leaf extract (Psidium guajava) is known for its hepatoprotective & antioxidant effects, but research on its impact on liver histopathology in the context of hypercholesterolemia remains limited. Objectives: To investigate the effect of Psidium guajava leaf extract on the histopathological picture of the liver in Wistar rats (Rattus norvegicus) with a hypercholesterolemia model. Methods: This experimental study used a post-test only control design. The experiment utilized a completely randomized design with four groups. Data analysis was performed univariately &bivariately. The research sample consisted of 28 Wistar rats, divided into 4 groups of 7 rats each. The rats were induced with a high-fat diet for 2 weeks to induce hypercholesterolemia, followed by treatment with guava leaf extract via gavage for 2 weeks. After termination, histopathological scoring of the liver was performed. Bivariate analysis was conducted using One-Way ANOVA & post hoc LSD tests. Key findings: Univariate analysis showed the highest mean liver damage score in the sick control group (4.00 ± 0.632) &the lowest in the group receiving guava leaf extract before hypercholesterolemia induction (1.33 ± 1.366). Bivariate analysis revealed significant differences between the healthy control &sick control groups (p = 0.00), as well as between the sick control & the guava leaf extract treatment group (p = 0.00). Guava leaf extract was found to reduce liver damage due to hypercholesterolemia, supporting its potential as an ameliorative & hepatoprotective agent. Conclusions: The administration of Psidium guajava leaf extract significantly influenced the histopathological score of the liver in Wistar rats induced with hypercholesterolemia. This result is supported by significant statistical differences in the histopathological liver scores across the four groups overall
Natural Antifungal: Garlic Extract's Activity Against Candida parapsilosis in Otomycosis
Background: Otomycosis is a common ear infection with a high recurrence rate due to resistance to standard antifungal drugs. Alternative therapies are needed, one of which is using garlic (Allium sativum) which is known to have antifungal effects. Objectives: This study aims to evaluate the activity of garlic extract (Allium sativum) as an antifungal against the growth of Candida parapsilosis fungus from otomycosis patients in vitro. Methods: A true experimental study with a posttest only control design using the microdilution method to determine the minimum inhibitory concentration (MIC) and the minimum fungisidal concentration (MFC). The sample consisted of 9 treatment groups, including garlic extract concentrations (6.25 mg/mL, 12.5 mg/mL, 25 mg/mL), ketoconazole positive control, 10% DMSO control, and negative control. Data analysis uses the Kruskal Wallis and Post-Hoc Mann Whitney tests. Key findings: The results of univariate analysis showed significant differences in each treatment group with bivariate analysis showing a significant relationship between extract treatment on fungal growth inhibition in the growth inhibition of Candida parapsilosis fungus with p-value P=0.021 (P<0.05). The value of MIC was found at a concentration of 6.25 mg/mL, while MFC was at a concentration of 12.5 mg/mL with an inhibition percentage of 99.67%. Conclusions: Garlic extract has the potential as an alternative antifungal therapy against infections caused by Candida parapsilosi
Pendampingan dalam Pembentukan Embrio KIR pada Siswa SMAN 1 Rawalo
Kelompok Karya Ilmiah Remaja (KIR) dapat ditumbuhkembangkan di lingkungan sekolah, untuk mewadahi potensi dan minat siswa di bidang ilmu pengetahuan dan teknologi. Selain itu, keberadaan KIR juga dapat meningkatkan prestasi sekolah dan kualitas siswa melalui kegiatan ekstrakurikuler pilihan. Beberapa prestasi telah di raih oleh siswa SMAN 1 Rawalo, namun di luar bidang karya ilmiah, karena wadah untuk KIR belum tersedia. Atas dasar kondisi tersebut maka, pihak sekolah SMAN 1 Rawalo, menghendaki dilakukan pendampingan untuk membentuk embrio kelompok KIR. Kegiatan ini dilakukan dengan metode partisipatif dengan tujuan untuk menemukenali potensi dan minat siswa dalam bidang ilmu pengetahuan dan teknologi, agar dapat mewadahinya dengan benar. Hasil kegiatan menunjukkan bahwa minat dan potensi siswa dapat dikelompokkan ke dalam tiga bidang, yaitu sains, sosial dan teknologi. Siswa juga memiliki ketertarikan untuk mengikuti lomba-lomba sains dan lomba karya ilmiah, kegiatan pendampingan masih berlanjut serta embrio KIR yang dirintis mengalami perkembangan yang baik.
Kata kunci: pendampingan, pembentukan kelompok KIR, SMAN 1 Rawal
Karakterisasi Sifat Fisik dan Aktivitas Antioksidan Lotion Daun Awar – Awar (Ficus septica)
Awar – awar (Ficus septica) biasa digunakan untuk mengobati penyakit kulit. Ekstrak etanol daun awar – awar memiliki aktivitas antioksidan. Daun awar – awar berpotensi dikembangkan menjadi sediaan farmasi. Daun awar – awar mengandung lapisan lilin yang kemungkinan dapat mengakibatkan ketidakcampuran dengan bahan pembawa sediaan lotion yang berbahan dasar air. Penelitian mengenai formulasi, karakterisasi sifat fisik dan aktivitas antioksisan ekstrak etanol daun awar – awar perlu dilakukan. Penelitian ini merupakan eksperimental laboratorium yang meliputi ekstraksi daun awar – awar menggunakan etanol dengan metode maserasi, formulasi lotion ekstrak daun awar – awar dengan konsentrasi ekstrak 1,5%, 2% dan 2,5%, karakterisasi sifat fisik dan aktivitas antioksidan lotion dengan metode peredaman DPPH. Semua formula lotion memenuhi persyaratan organoleptis, homogenitas, daya lekat, daya sebar, viskositas dan pH. Daya lekat dan viskositas meningkat seiring meningkatnya konsentrasi ekstrak. Daya sebar menunjukan pola yang sebaliknya. Aktivitas antioksidan control negative, lotion 1,5%, lotion 2%, lotion 2,5% dan control positif lotion citra berturut – turut 41,532±0,4 %; 47,858±0,4; 49,403±1,1; 51,966±1,6% dan 53,954±0,4. Prosentase peredaman semuanya berbeda terhadap control negative (p<0,05). Lotion yang mengandung ekstrak awar – awar 2,5% menunjukan persen peredaman yang berbeda terhadap lotion 1,5 dan 2% meskipun masih berbeda juga dengan control positif (p<0,05)
Formulasi Sediaan Lip Cream dengan Pewarna Alami Ekstrak Bunga Belimbing Wuluh (Averrhoa bilimbi L.)
Lip cream diminati wanita karena memiliki tekstur semi padat yang memudahkan diaplikasikan pada bibir dengan berbagai variasi warna. Bunga belimbing wuluh (Averrhoa bilimbi L.) memiliki kandungan antosianin yang menghasilkan pigmen berwarna merah dan dapat dimanfaatkan sebagai pewarna alami untuk lip cream. Penelitian ini bertujuan untuk mengetahui konsentrasi ekstrak bunga belimbing wuluh yang menghasilkan lip cream dengan sifat fisik dan stabilitas paling baik. Penelitian dilakukan secara eksperimental. Proses ekstraksi bunga belimbing wuluh dengan metode maserasi menggunakan pelarut etanol 96%. Pembuatan lip cream menggunakan ekstrak kental bunga belimbing wuluh dengan konsentrasi FI 4%, FII 6%, FIII 8%, dan FIV 10%. Uji sifat fisik lip cream meliputi organoleptis, homogenitas, pH, viskositas, daya sebar, daya lekat, uji hedonik, dan uji iritasi serta uji stabilitas fisik dengan metode freeze thaw. Hasil penelitian menunjukkan keempat formulasi lip cream memenuhi syarat sifat fisik dan stabilitas fisik yang baik serta tidak mengiritasi kulit. Formula lip cream yang menghasilkan sifat fisik dan stabilitas fisik paling baik serta paling disukai responden yaitu formula IV dengan konsentrasi ekstrak bunga belimbing wuluh sebesar 10%
Determining the Distribution of Nickel Enrichment Zone in Sorowako Area and Surroundings, Nuha District, East Luwu Regency, South Sulawesi
The downstream policy forces the nickel mining sector to build new smelters which are claimed to be able to process nickel ore material in the limonite to saprolite zones, so a method is needed to prove the existence of nickel potential in the limonite zone. In this case, the method used is modeling nickel enrichment zone deposits. This research uses collar data of 218 drill points and geological domain data of 8,092 datums. The optimal potential for laterite nickel deposits is explored by entering the geological control of the deposit domain and expressing the nickel enrichment zone model so that the slice volume percentage in the limonite and saprolite zones is known. Based on the results of modeling the nickel enrichment zone in the research area located in Sorowako, South Sulawesi, it shows that the nickel enrichment zone has a volume of 4,190,500 cubic meters (m3). The nickel enrichment zone is known to have no intersection with the bedrock zone, but has an intersection with limonite domains of 33%, and saprolite domains of 67%. As additional information, it is known that the laterite deposits are around 30 meters thick with a nickel enrichment zone at a depth of 10 meters to 25 meters from the surfac
PENGARUH PEMBERIAN SEDUHAN DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA MENCIT (Mus musculus) DIABETES MELITUS
Diabetes mellitus (DM) is a non – communicable disease due to hyperglycemia, impaired insulin secrection, or impaired insulin performance. The purpose of this study was to determine whether the steeping of star fruit leaves (Averrhoa bilimbi L.) affects lowering blood glucose levels. This type of research is an experiment groups. This study used 30 mice weighing 20-30 grams, 8 weeks old, divided into 5 groups, namely negative and positive controls, as well as treatment groups with doses 250, 500, and 500 mg/kg BW, with a period of intervention for 14 days through given oral. Statistical analysis was performed using the Paired T-test, One-Way ANOVA test, and Post Hoc LSD test. The results of the Paired T-test test showed a significant value in the opposing group, doses of 250 mg/kg BW, 500 mg/kg BW, and 750 mg/kg BW of 0,000 (p<0,05). The One-Way ANOVA test showed a significant value of 0,000 (p<0,05) which means there is a significant difference in the decrease in blood glucose levels, that the Post Hoc LSD test showed that the treatment group with a dose of 250, 500, and 750 mg/kg BW was effective in reducing fasting blood glucose levels by showing a significant difference of 0,000 (p<0,05). These results indicate that there is an effecf of decreasing blood glucose levels on the 25th day in the treatment group given steeped bean leaves
Pelatihan Pemanfaatan Artificial Itelligence dalam Pembelajaran Pada Guru SMA di Kabupaten Batanghari
Pelatihan ini bertujuan untuk meningkatkan kesadaran dan pemahaman guru tentang potensi artifisial intelligence dalam pendidikan serta memberikan keterampilan praktis dalam menggunakan alat dan sumber daya artifisial intelligence dalam perencanaan pembelajaran. Metode pelaksanaan pelatihan dilakukan sebanyak empat tahapan antara lain persiapan dan perencanaan, pelaksanaan pelatihan, evaluasi pelaksanaan, dan pelaporan serta refleksi. Peserta pelatihan adalah guru-guru SMA di Kabupaten Batanghari. Hasil pretest menunjukkan bahwa para guru telah mengenal pemanfaatan artifisial intelligence dalam perencanaan pembelajaran, keberminatan untuk menggunakan artifisial intelligence, dan masih belum dapat untuk mempelajari pemanfaatan AI. Hasil posttest menunjukkan bahwa mayoritas para guru telah telah mengetahui pemanfaatan peggunaan AI, cara penggunaan AI secara praktik, dan sangat berminat dalam mengimplementasikan AI dalam perencanaan pembelajaran. Dengan demikin pelatihan ini mampu untuk memberikan pemahaman guru dan mengimplementasi pemanfaatan AI dalam merancang perencanaan pembelajaran yang diharapkan dapat meningkatkan kompetensi guru agar relevan dengan era saat ini.This training aims to enhance teachers' awareness and understanding of the potential of artificial intelligence in education, and to provide practical skills in using artificial intelligence tools and resources in lesson planning. The training is conducted in four stages: preparation and planning, training implementation, evaluation of implementation, and reporting and reflection. The training participants are high school teachers in Batanghari Regency. Pretest results showed that the teachers were already familiar with the use of artificial intelligence in lesson planning, were interested in using artificial intelligence, but were still unable to learn how to utilize AI. Post-test results indicated that the majority of teachers had already understood the use of AI, how to use AI in practice, and were very interested in implementing AI in lesson planning. Thus, this training was able to provide teachers with an understanding and implementation of AI in designing lesson plans, which is expected to improve teachers' competencies to be relevant to the current er