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An IoT-Enabled mHealth Sensing Approach for Remote Detection of Keratoconus Using Smartphone Technology
No full textKeratoconus (KC) is a progressive eye disease and a major cause of vision impairment and blindness worldwide. Early diagnosis is crucial for effective management, yet conventional diagnostic methods rely on expensive and bulky imaging devices, limiting accessibility, especially in resource-constrained settings. This paper introduces a novel smartphone-based approach for the early detection of KC, leveraging screen-projected Placido disc patterns and an advanced image processing framework. Unlike traditional corneal topographers, our method utilizes a unique Placido disc projection technique and a machine learning-based classification model to analyze corneal irregularities with high precision. With a sensitivity of 96.08%, specificity of 97.96%, and overall accuracy of 97% on our dataset, the proposed system demonstrates exceptional diagnostic reliability. By transforming a standard smartphone into an effective screening tool, this innovation provides an affordable, portable, and user-friendly solution for early KC detection, bridging the gap in eye care accessibility and reducing the global burden of undiagnosed keratoconus
SWCPC 438 #13 Frederick Horsburgh, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
Biofilm Dispersal and Wound Infection Clearance With Preclinical Debridement Agents
No full textBiofilms complicate wound care by causing recurrent infections that are often resistant to debridement and are highly antibiotic-tolerant. We investigated whether the addition of a biofilm dispersal agent could improve the efficacy of debridement. The previous studies have indicated that a glycoside hydrolase cocktail of alpha-amylase and cellulase can act as a potent biofilm dispersal agent. With in vitro and ex vivo Pseudomonas aeruginosa biofilm models, we compared glycoside hydrolases against other, clinically relevant, enzymatic debridement agents (papain, bromelain, and collagenase). Glycoside hydrolase biofilm dispersal was dose-dependent. However, at doses of 1% or above, glycoside hydrolases outperformed, or were comparable, to other enzymatic debridement agents. With our in vivo surgical wound infection model, we evaluated biofilm dispersal using infection dissemination as a proxy. We found that sharp debridement followed by multiple glycoside hydrolase treatments enhanced biofilm dispersal. Furthermore, a single dose of glycoside hydrolase in combination with debridement decreased infection load in acute wounds. Similarly, when we treated established 5-day-old infections, we saw a decrease in infection load and no infection dissemination. Overall, our data suggest that debridement enhances the efficacy of a topical antibiotic ointment, allowing for greater infection clearance
SWCPC 438 #3 John Brigham Wilson, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
SWCPC 438 Negatives #18 Allen M. McFaddin, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
SWCPC 438 Negatives #63 Oliver Loving (duplicate), undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
Manuscript of 100-Year History of FBC Lubbock by Weston A. Pettey - Part 1 - Chapters 1-9.
No full textManuscript notes from Dr. Weston A. Pettey's book The First Baptist Church of Lubbock, Texas 1891-1991
SWCPC 438 Negatives #40 Captain Richard King, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
SWCPC 438 #7 C. C. Slaughter, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.
SWCPC 438 #55 James H. Parramore, undated.
No full textThe collection features portraits of sixty-one prominent cattle ranchers, both male and female, who were considered to be the “Cattle Kings of Texas.