Campbell University
CU FIND (Campbell University, Catherine W. Wood School of Nursing)Not a member yet
9287 research outputs found
Sort by
3-1,2-Dithiole-3-Thione as a Potentially Novel Therapeutic Compound for Sepsis Intervention
No full textThrough the history of modern medicine, bioactive components in natural products have been either employed directly as medicines or used as prototypes for synthetic drug development. This brief Research Highlights paper considers 3-1,2-dithiole-3-thione (D3T), a member of the 1,2-dithiole-3-thiones-compounds which may naturally occur in cruciferous vegetables. Among 1,2-dithiole-3-thiones, D3T is the most potent member with regard to the capacity of inducing tissue defenses against oxidative and inflammatory stress. Oxidative and inflammatory stress is a major pathophysiological process involved in numerous human disorders, including cancer, cardiovascular diseases, neurodegeneration, and sepsis, to name just a few. This article surveys recent major research findings on D3T as an inducer of tissue antioxidative and antiinflammatory defenses and as a potential therapeutic modality for sepsis intervention
Disbursement Policy
No full textThe Disbursement Policy of the University is to ensure that all discretionary expenditures made from the University’s Restricted or Unrestricted Assets (managed, non-managed or endowed) are properly approved by the appropriate position within the University or the Executive Committee of the Board of Trustees
Design, synthesis and characterization of ogerin-based positive allosteric modulators for G protein-coupled receptor 68 (GPR68)
No full text
