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Development of a substance use disorders course for health professions students: From learning in the classroom to applying on the floors
No full textLa laberíntica Ciudad de México en la formación de la identidad de Dorotea Leyva en la familia vino del norte de la escritora Mexicana Silvia Molina
No full textPrevalence of Rome IV Functional Gastrointestinal Disorders in Children and Adolescents in the United States
No full text
Book review of Biblical Prophecy: Perspectives for Christian Theology, Discipleship, and Ministry by Ellen F. Davis
No full textIntegration of Biomedical and Psychosocial Issues in Pediatric Functional Gastrointestinal and Motility Disorders
No full textPsychological Factors May Play an Important Role in Pediatric Crohn\u27s Disease Symptoms and Disability
No full textOBJECTIVE:
To examine the relative contributions of disease activity and psychological factors to self-reported symptoms and disability in children with Crohn\u27s disease. STUDY DESIGN:
Participants (n = 127 children age 8-18 years) completed questionnaires on symptom severity and disability, as well as psychological measures assessing anxiety, depression, pain beliefs and coping. Disease activity was measured by the Pediatric Crohn\u27sDisease Activity Index. Structural equation modeling was used to test the effects of disease activity and psychological factors on symptomsand disability. RESULTS:
In the hypothesized model predicting symptoms, psychological factors (β = 0.58; P \u3c .001) were significantly associated with disease symptoms but disease activity was not. The model for disability yielded significant associations for both psychological factors (β = 0.75; P \u3c .001) and disease activity (β = 0.61, P \u3c .05). CONCLUSION:
Crohn\u27s disease symptoms in children and adolescents are not only driven by disease activity. Coping, anxiety, depression, and cognition of illness are important in the patient-reporting of symptom severity and disability. Physicians need to be aware that symptom self-reporting can be driven by psychological factors and may not always be simply an indicator of disease activity
