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A Study on the Stigma, Quality Of Life and Help Seeking Behaviour in an Urban Transgender Community
No full textPrevalence of Disordered Eating Behaviour and Body Dissatisfaction and Influence of Media Exposure on it among the College Students and Its Effects on the Self-Esteem
No full text
Study on Utilization of Antenatal Services and Out of Pocket Expenditure for Delivery Care in Tiruvallur District
No full textEstimated Total Cross-Sectional Area of Psoas Muscle as a Predictor of Postoperative Morbidity Following Gastrointestinal Surgeries: A Prospective Observational study
No full textA Clinical study for Validation of Novel Preoperative Score in Elective/Interval Laparoscopic Cholecyctectomy to Predict Difficult Gallbladder Surgery in General Surgery Department
No full textA Study on Maternal Serum Glycosylated Fibronectin as a Predictor of Pre Eclampsia in Antenatal Women between 20-36 Weeks of Gestational Age: A Prospective study
Get PDFINTRODUCTION:
Preeclampsia (PE) is associated with 10–15% of all maternal deaths during pregnancy and childbirth, making it the second-leading cause of maternal mortality, resulting in an estimated 76,000 maternal deaths annually1. PE also accounts for 25% of stillbirths and 25% of neonatal deaths. Over 99% of this maternal and fetal/ neonatal mortality attributed
to PE occurs in low-and middle-income countries, particularly Africa and the Indian subcontinent. Previous studies suggest that mortality rates could be considerably reduced if clinicians were more aware of the likelihood that PE could develop4. PE was redefined by the American
College of Obstetricians and Gynaecologists (ACOG) in 2013.
AIMS AND OBJECTIVES:
To compare the maternal serum glycosylated fibronectin levels in normotensive, mild and severe pre-eclampsia and its use in prediction of severity of pre-eclampsia.
MATERIALS AND METHODS:
Source of data: AN patient attending OP, IP at GRH Madurai
Study Design: Open label, comparative, prospective study
Study Period: One year.
Sample Design: simple random sampling.
Sample Size: 200.
Inclusion Criteria:
a. All pregnant mothers between GA 32 to 34 weeks irrespective of hypertensive status and risk factors present so includes normotensive women, chronic / gestational hypertension, preeclamptic and eclamptic women.
b. Includes singleton and twin pregnancies.
Exclusion Criteria:
a. Pregnancies with fetal anomalies are not included in the study group.
b. Whilst twin pregnancies are included, triplets and quadruplets are excluded from study.
c. Subjects with chronic renal disease, chronic heart ailments are excluded.
CONCLUSION:
Our findings show that in pregnant women with hypertension, the glycosylated fibronectin POC test has a high predictive value for preeclampsia occurring within 10 days of testing. It will be a useful cost-effective tool in low-resource settings for appropriate triage and timely referral to higher centres, and it can be used in tertiary centres to triage PE patients to inpatient vs. outpatient management. Larger studies are needed in the future to determine the sensitivity and specificity that can reduce the
frequency of biochemical and sonographic monitoring in hypertension cases during pregnancy
Pregnancy Associated Acute Kidney Injury in Patients with Hypertensive Disorders of Pregnancy
No full textPregnancy associated acute kidney injury is a majority clinical challenge because it poses a risk to 2 lives mother and fetus. It is largely due to preventable obstetrical complications, but can be caused by certain pregnancy specific diseases. Pregnancy hypertensive complications, like preeclampsia, eclampsia/HELLP syndrome are the leading cause. Puerperal sepsis and obstetrical hemorrhage still account for AKI in the postpartum period in addition to Preeclampsia/HELLP syndrome. The implementation of specific intervention for the prevention and management of sepsis and hypertensive complications in pregnant women may decrease the burden of Pregnancy associated AKI. Incidence of AKI in pregnancy has been decreased in developing countries with improved maternal prognosis .But the fetal mortality is very high even in developed countries. CONCLUSION: • In our study 42% of the patients age is between 19-25 years and 30% of patients is between 26-30 years, followed by 28% of patients age is between 31-35 years. • In our study (60%) are primigravida, 40% are Multigravida • 62% of the cases are in the BMI level of less than 25. • Only one case had BP less than 140/90 mm of Hg. 99% patients had BP>140/90 mm of Hg. • The average blood urea levels before delivery were 27.05mg/dl, after delivery urea level increased to 43.84mg/dl. • In our study the blood creatinine levels of the participants 59% were 1mg/dl to 2mg/dl, 25% were 2 to 3 mg/dl and 16% were >3mg/dl. • Mean uric acid level is significantly higher in AKI stage 3 when compared with AKI stage 1 & 2. • Mean serum pottaissium level is significantly higher in AKI stage 3 when compared with AKI stage 1 & 2. • 24 hrs urine protein level also significantly higher in AKI stage 3 cases when compared with other two stages. • Urine albuminuria level is significantly higher in AKI stage 3 cases. • Out of 100 cases, 4 maternal death in AKI stage 3 and 8 neonatal death is in AKI stage 3 and other 5 neonatal death is in AKI stage 2 group. ❖ In our study concludes pregnancy related AKI is still a common accurrence in our country. In this study, severe pre-eclampsia was the most frequent etiology (50 cases) followed by preeclampsia 23 cases, followed by 13 cases eclampsia, 5 cases HELLP syndrome and sepsis 4 cases.. ❖ Pregnancy associated AKI has been diagnosed and managed, the postpartum management of such patients should include a screening urea and creatinine along with urinary dip stick and liver function test. ❖ In this context, prevention is the best and least expensive solution. Prenatal care and greater access to emergency obstetric services, could decrease the pregnancy related AKI and its consequences
