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A Comparison of Conventional Blade Laryngoscopy with Video Assisted Blade Laryngoscopy in the Management of Predicted Difficult Airway: A Randomized Control study
No full textRole of Presurgical Erector Spinae Plane Block Versus Paravertebral Block in Pain Control and Hemodynamic Stability after Modified Radical Mastectomy: A Prospective Randomized Trial
No full textComparison of Ultrasound Guided Transversus Abdominis Plane Block and Erector Spinae Plane Block for Post Operative Analgesia in Inguinal Hernia Repair
No full textEvaluation of Clinical Efficacy of Urai Mathirai as Immuno Modulator
No full textThe question of efficacy of Urai Mathirai as Immunomodulator and its usage to children was tested with a Null hypothesis that Urai Mathirai is not beneficial as an Immunomodulator. To test this Urai Mathirai was prepared meticulously as per Hospital pharmacopeia of Indian medicine. However, the Bullet shaped rubbing pills were replaced with 50mg tablets as per specific SOP.
The tablet matched with the standards prescribed by PLIM and also other parameters for tablets. While preparing all the drugs were authenticated. Pharmacognosy, Physico chemical and phytochemical testing was done as per guidelines. The results revealed the purity of the drug as it is free from heavy metals, Aflatoxins, and Microbial load.
In vitro studies for Antioxidant, Anti- Inflammatory and Immunomodulatory effects proved the basic claim of the drug and anti-microbial activity proved the efficacy of drug against certain bacteria. In vivo Safety and Pharmacological studies revealed Nontoxic nature and effectiveness of drug. Anti-inflammatory analgesic and Immunomodulator activity of the drug reassured its traditional claim.
Clinical trial carried out helped in proving the efficacy of Urai Mathirai on par with the official siddha formulation Thaleesathi chooranam in controlling repeated respiratory infections. The outcome measures clearly assured the efficacy of Urai Mathirai and proved that Urai Mathirai decreases the disease burden. Four main variables tested helps in proving the claim of the drug’s use in Mantham, Kanam and Loss of appetite.
CONCLUSION:
Its concluded that preclinical and clinical studies carried over prove that Urai Mathirai possess immuno modulator activity evinced through in vivo Immunomodulatory studies and also by reduction in repeated respiratory infections and disease burden reduction in Clinical trials.
RECOMMENDATIONS:
• Chronic toxicity study is the limitation and is to be carried out.
• Large sample randomized and Blinded trials will help to mainstream this drug.
• The efficacy of Urai Mathirai in Bronchial asthma and COPD is to be evaluated
Open Labeled Randomized Controlled Clinical Trial on Impaired Glucose Tolerance (IGT) (Munneerizhuvu)
No full textDevelopment and Evaluation of Traditional Polyherbal Formulation for Antidiabetic Activity
No full textEffectiveness of Nursing Care Bundle on Prevention of Ventilator Associated Pneumonia among Mechanically Ventilated Patients admitted in Selected Hospitals, Erode, Tamilnadu
No full textA Quasi Experimental study to Assess the Impact of Integrated Pathway (IP) Upon Capacity Building of Nurses in Caring of People affected with Ebola Virus Disease at Selected Setting
No full textAn Experimental study to Evaluate the Effectiveness of Acupressure Shiastu on Enhancing Lactation among Primipara Mothers by Estimating Serum Prolactin Level at Selected Hospitals, Kanchipuram District
No full textInitiation of breast milk within the first hour after birth is found to be
healthiest food for the newborn. The world health organization recommends
exclusive breast feeding for the infant 0-6months. The exclusive breast feeding is
defined as giving breast milk or no other food or drink, not even sips of water
except oral rehydration solution and vitamin supplements for the first 6 months. A
global target was set by world health assembly to increase the exclusive breast
feeding rate globally to 50% by 2025.
Breast feeding is also reduces the risk of diabetes, osteoporosis, breast,
endometrium and ovarian cancer in later years of women’s life. Not only this the
breast feeding is also got greater advantages like; breast milk is cheap, readily
available for 24x7, no time is necessary for preparation available at correct
temperature and safe for the newborn. The breast feeding helps in the reduction of
baby’s risk for developing type 1 diabetes, sudden death syndrome, pneumonia,
cough, cold gastro intestinal problems such as constipation, vomiting diarrhea,
indigestion and prevents from other infections and diseases such as; urinary tract
infections, ear infections, childhood cancers, celiac disease, chrohn’s disease, heart
disease, liver disease, ulcerative colitis, meningitis etc., The inadequate breastmilk
production will be major causes for the mothers to stop breast feeding or to start
early weaning habits in newborn. The major issues which are cited for inadequate
milk production are latching issues on feeding, infant health problems or
inadequate calorie intake of the mothers during the process of lactation.
STATEMENT OF THE PROBLEM
AN EXPERIMENTAL STUDY TO EVALUATE THE EFFECTIVENESS
OF ACUPRESSURE-SHIASTU ON ENHANCING LACTATION AMONG
PRIMIPARA MOTHERS BY ESTIMATING SERUM PROLACTIN LEVEL AT
SELECTED HOSPITALS, KANCHEEPURAM DISTRICT
OBJECTIVES
1. to assess the pre test and post test level of knowledge on exclusive
breast feeding and serum prolactin level among primipara mothers.
2. to evaluate the effectiveness of Acupressure-shiastu among primipara
mothers in experimental and control group.
3. to find the association between the selected demographic variables and
post-test level of serum prolactin among primigravida mothers
4. to find out the association between the selected demographic variables
and Knowledge among primigravida mothers
HYPOTHESIS
H1: There will be a significant difference in pretest and post test level of serum
prolactin level among primipara mothers in experimental group and control group.
H2: There will be a significant difference in knowledge and practice on exclusive
breast feeding among primipara mothers in experimental group and control group
RESEARCH METHODOLOGY
True experimental pre test post test design was adopted and probability
Simple Random sampling was used to select the samples. Based on the sampling
criteria totally 326 samples were selected for this study, out of this 163 samples
were grouped in experimental group and treated with acupressure shiatsu and
educational intervention and 163 samples were grouped in control group and
treated with educational intervention regarding exclusive breast feeding. On 3 rd
day pre intervention stage, LATCHES breast feeding assessment and charting
system was used to identify mothers with insufficient breast milk production. The
mothers blood samples had been collected in pre intervention stage then
experimental group mothers received acupressure-shiastu, the control group
received instructional module alone. On the 5" day, the mothers blood sample had
been collected for sr. prolactin level on post intervention stage.
RESULTS
ACUPRESSURE — SHIATSU GROUP
In experimental group pre test serum prolactin level shows the mean score
was 68.6135, standard deviation of 12.45601 with the standard error mean of
0.97563. In post test the mean score was 103.9571,standard deviation of 10.20430
and the standard error mean was 0.79926. This proves that the serum prolactin
level was increased and statistically significant with the t value 32.704 at p<0.001.
EDUCATIONAL INTERVENTION GROUP
In pre test shows the mean score was 69.295, standard deviation was
12.647 with the standard error mean of 0.99060. In post test the mean score was
98.896 with the standard deviation of 12.568 and the standard error mean was
0.984. This proves that the knowledge score in the control group was improved
and statistically significant with the t value 33.505 at p<0.001.
CONCLUSION
The study concluded that acupressure shiatsu. was effective in enhancing
lactation and educational intervention was also effective in improving the
knowledge score on exclusive breast feeding and LATCHES score among
primipara mothers
IMPLICATIONS
The findings of the study has several implications for nursing practice,
nursing education, nursing administration and nursing research. The study
findings helps to enhance the lactation and knowledge on exclusive breast feeding
among the primipara mothers. The nursing professionals working in hospital and
community knowing the self-help techniques of Acupressure-shiastu in enhancing
lactation and helps in planning and implementation of health teaching. Nurse
educators should formulate the educational intervention programme about
lactation enhancement, complications of inadequate lactation and its management
within institution by using the alternative therapies especially the technique of
Acupressure shiatsu. Nurse administrator should plan of breast feeding
programme and strategies about BHFI- Baby friendly Hospital Initiatives
A Study of Obstetric and Perinatal Outcome in Epilepsy Complicating Pregnancy
Get PDF100 women admitted in Labour/ Antenatal ward with seizure disorder were taken up for the study.
• Mean age of patients with epilepsy is 25.5.
• Primiparous women with epilepsy were the predominant admission.
• Generalized tonic clonic seizures were the most common presentation of seizure at 45%
• Most of the women had new onset seizures – 41%.
• Many had less than 5 years of seizure disorder. Seizure free interval was not significant as most women were admitted with an episode of seizure commonly antepartum seizures (50%).
• 32% of women remained seizure free throughout pregnancy.
• Third trimester seizures were common in our study 32%.
• Monotherapy was the preferred treatment at 56%. 10% of women required no antiepileptics.
• Carbamazepine was the most common treatment of choice 34% followed by Levetiracetam at 29%.
• 43% had abnormal EEG findings.
• 30% had abnormal radiographical finding commonly sclerotic lesions (13%).
• Gestational hypertension is the most common associated comorbidity -16%.
• There were 2 cases of death purely due to seizure disorder – uncontrolled status epilepticus causing SUDEP.
• Cesarean section rates were slightly higher than normal vaginal deliveries.
• Postpartum hemorrhage is the most common complication in immediate postpartum period.
• Average baby weight was 2.3 to 2.7kg.
• There was 1/4th preterm deliveries. Overall perinatal outcome was good.
• 23% of the babies were low birth weight.
• Low birth weight to polytherapy relationship was not much significant in this study.
CONCLUSION:
Epilepsy complicating pregnancy come under high risk pregnancies and needs to be carefully evaluated and started on treatment earlier.
• Earlier diagnosis, booking, early treatment has significantly reduced the recurrence of seizures, obstetric and perinatal complications. Risk of low weight babies is present but it is not of much significance as overall outcome of babies are good. The congenital malformations are also very much reduced due to use of safer new antiepileptic drugs and regular intake of folic acid tablets.
• A Multidisciplinary management of the disease is required with an obstetrician, pediatrician and neurologist for good obstetrics and perinatal outcome.
• Regular followup of patient with neurologist is required postnatally to prevent recurrence of seizure and adjusting dosage of drugs for breastfeeding. Intake of antiepileptics is not a contraindication for breastfeeding. Breastfeeding should be encouraged.
• Counselling should be given about oral contraceptive pills as there is higher rate of failure due to intake of antiepileptics drugs. Intrauterine contraceptive devices should be advised in patient who want to defer future pregnancies.
Early diagnosis, referral to higher centres with availability of neurologists and imaging modalities is needed for patients with epilepsy so that proper care can be given and thereby reduce maternal and perinatal morbidity and mortality