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A Study on Diastolic Dysfunction in Newly Diagnosed Type 2 Diabetes Mellitus and its Correlation with HbA1c
No full textA Study of Association of Serum Calcium Level in Pregnant Females with Hypertensive Disorders in Government Vellore Medical College and Hospital, Vellore
No full textINTRODUCTION:
Preeclampsia is a frequent disease with an incidence of 5 to 7% among the general population. Preeclampsia is associated with a five-fold increase in perinatal mortality. In general, there is disagreement about many aspects of
hypertensive disorders of pregnancy, including the diagnosis, classification, and management. Pregnancy is a period of high calcium demand because of fetal requirement. Many compensatory mechanisms comes into action to prevent
calcium depletion from maternal skeletal reserves, like increased absorption, reduced renal losses, etc. But in pre-eclampsia, all these compensatory mechanisms tend to function abnormally. The studies have shown a strong
correlation of calcium with preeclampsia. It has been proven that inverse association exists between calcium intake and development of hypertension during pregnancy. This study intends to find the serum calcium level and its association with hypertensive disorders in pregnancy.
AIM OF THE STUDY:
1) Identify the prevalence of hypocalcemia in pregnant females with hypertensive disorders of pregnancy.
2) Assess the compliance of calcium intake in the study group.
METHODOLOGY:
100 patients who were diagnosed, or highly suspected to have
hypertensive disorders of pregnancy, were selected randomly from the outpatient/in-patient wards of the obstetrics and gynecology department. Informed consent was obtained, and data collected based on the preformed questionnaire.
Required investigations were done, after general and systemic examination. Of importance, blood pressure, corrected calcium, urine protein (by dipstick) were
checked in all the patients. Compliance of drug intake was assessed from the questionnaire.
Analysis was done, to find the average calcium level among the study population, and its correlation between severity of the disease.
RESULTS:
Statistical analysis was carried out to find any association between serum calcium and severity of the disease. The mean calcium level varied significantly (reduction in the level) across the disease spectrum, namely, gestational hypertension, pre-eclampsia, and pre-eclampsia with severe features. Analysis also revealed significant association between serum calcium and other parameters, like bloop pressure, proteinuria. Compliance of drug intake was
assessed, and there was significant association between compliance and the severity of the disease.
CONCLUSION:
The findings of this study show that, there was significant association between serum calcium and hypertensive disorders of pregnancy, and its severity. Drug intake in the community was an important contributing factor, towards reducing the risk of developing severe disease
A Study on Serum Creatine Phosphokinase and Hypoalbuminemia in Assessing the Severity of Organo Phosphorus Poisoning
No full textBacteriological Spectrum and Antimicrobial Resistance Profile in Acute Exacerbations of Chronic Obstructive Pulmonary Disease at a Tertiary Care Centre in Kanyakumari District
No full textExpression of Tumour Associated Macrophages at Tumour Invasive Front in Colorectal Adenocarcinoma and Its Clinicopathological Correlations
No full textA Study of Histomorphological Spectrum of Skin Adnexal Tumours and its Clinico-Pathological Correlation by Prospective and Retrospective Study
No full textThe Utility of Perinatal Autopsy in CNS Malformations: A Cross-Sectional Study in a Tertiary Health Care
No full textClinical Utility of Hematological Parameters in Patients with Acute Coronary Syndrome Visiting the Emergency Department with Acute Chest Pain
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