727 research outputs found
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Strategic Migration Policy - HD.SMP 1.0 [research data]
As part of the Strategic Migration Policy project, a dataset (HD.SMP 1.0) was developed that systematizes and codes bilateral migration agreements of the destination countries/regions of the European Union and its member states, Switzerland, Norway, the United States, Canada, New Zealand, Australia, and the United Kingdom between 1990-2022. The dataset includes 1457 agreements and conventions, which were recorded using categories that provide information on parties involved, legal status, scope, degree of informality, and degree of externalization. It excludes agreements aimed exclusively at regulating labor migration.
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Im Rahmen des Projektes „Strategische Migrationspolitik“ wurde ein Datensatz (HD.SMP 1.0) entwickelt, der bilaterale Migrationsabkommen der Zielländer/Regionen der Europäischen Union und ihrer Mitgliedsstaaten, der Schweiz, Norwegens, der Vereinigten Staaten, Kanadas, Neuseelands, Australiens sowie des Vereinigten Königreichs zwischen 1990-2022 systematisiert und kodiert. Der Datensatz beinhaltet 1457 Abkommen und Übereinkünfte, die anhand von Kategorien erfasst wurden und die Auskunft über beteiligte Parteien, rechtlichen Status, Umfang, Informalitäts- und Externalisierungsgrad geben. Er schließt Abkommen aus, die ausschließlich auf die Regelung von Arbeitsmigration abzielen
Single Crystals of Insoluble Porous Salicylimine Cages [Data]
Porous organic cages (POCs) are meanwhile an established class of porous materials. Most of them are soluble to a certain extend and thus processable in or from solution. However, a few of larger salicylimine cages were reported to be insoluble in any organic solvents and thus characterized as amorphous materials. These cages were now synthesized as single-crystalline materials to get insight into packing motifs and preferred intermolecular interactions. Furthermore, the pairs of crystalline and amorphous materials for each cage allowed to compare their gas-sorption properties in both morphological states
Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]
Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-terminal FERM domain binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-enriched membranes. A newly published autoinhibitory structure of talin-1, where the known PIP2 interaction sites are covered up, lead us to hypothesize that a hitherto less examined loop insertion of the FERM domain acts as an additional and initial site of contact. We evaluated direct interactions of talin-1 with a PIP2 membrane by means of atomistic molecular dynamics (MD) simulations. We show that this unstructured, 33-residue-long loop strongly interacts with PIP2 and can facilitate further membrane contacts, including the canonical PIP2 interactions, by serving as a flexible membrane anchor. Under force as present at FAs, the extensible FERM loop ensures talin to maintain membrane contacts when pulled away from the membrane by up to 7 nm. We identify key basic residues of the anchor mediating the highly dynamic talin-membrane interaction. Our results put forward an intrinsically disordered loop as a key and highly adaptable PIP2 recognition site of talin and potentially other PIP2-binding mechano-proteins.
This dataset contains setup scripts, molecular dynamics parameters, input files and derived data from the molecular dynamics simulations of this paper available at https://graeter-group.github.io/paper-talin-loop/ or https://doi.org/10.1016/j.bpj.2023.02.020
Katalog inschriftloser Monumente
Die hier zusammengefassten Tabellen verzeichnen die im Rahmen der Erstellung meiner Dissertation gesammelten, nicht-inschrifttragenden Steinmonumente aus dem Untersuchungsgebiet entlang von Oberrhein und Neckar, aus Deutschland und Frankreich. Aufgenommen wurden Monumente und Fragmente von solchen Typen von Monumenten, welche üblicherweise Inschriften tragen können, dies aber im Einzelfall nicht tun bzw. bei denen keine Inschrift überliefert ist
Diffuse Domain Approach for Flexible Needle Insertion and Relaxation [data]
Needle insertion simulations play an important role in medical training and surgical planning. Most simulations require boundary conforming meshes, while the diffuse domain approach, currently limited to stiff needles, eliminates the need for meshing geometries.
In this paper the diffuse domain approach for needle insertion simulations is first extended to the use of flexible needles with bevel needle tips, which are represented by an Euler-Bernoulli beam. The model parameters are tuned and the model is evaluated on a real-world phantom experiment. Second, a new method for the relaxation of the needle-tissue system after the user releases the needle is introduced. The equilibrium state of the system is determined by minimizing the potential energy.
The convergence rate of the coupled Laplace equations for solving the Euler-Bernoulli beam is 1.92±0.14 for decreasing cell size. The diffuse penalty method for the application of Dirichlet boundary conditions results in a convergence rate of 0.73±0.21 for decreasing phase field width. The simulated needle deviates on average by 0.29 mm compared to the phantom experiment. The error of the tissue deformation is below 1 mm for 97.5% of the attached markers. Two additional experiments demonstrate the feasibility of the relaxation process.
The simulation method presented here is a valuable tool for patient-specific medical simulations using flexible needles without the need for boundary conforming meshing. To the best of the authors' knowledge this is the first work to introduce a relaxation model, which is a major step for simulating accurate needle-tissue positioning during realistic medical interventions
Codices Palatini germanici – Cod. Pal. germ. 496-670
Here you can find the descriptions of the German Palatine manuscripts (Cod. Pal. germ. 496-670) as published in the manuscripts catalog "Die Codices Palatini germanici in der Universitätsbibliothek Heidelberg (Cod. Pal. germ. 496-670)", edited by Pamela Kalning, Matthias Miller and Karin Zimmermann with the assistance of Lennart Güntzel, Wiesbaden 2014 (Kataloge der Universitätsbibliothek Heidelberg 11). The description for each manuscript was subsequently recorded as TEI-XML file by XML encoding in accordance with TEI-P5 using GND standard vocabulary.
These TEI files follow an outdated TEI schema originally developed at the Herzog August Bibliothek Wolfenbüttel and contain some ad hoc solutions which were chosen pragmatically in Heidelberg and which do not always comply with the TEI Guidelines. A future migration of the dataset into a fully TEI-compliant format is considered as desirable
Deutsch-Französische Kunstvermittlung 1870–1960 [data and software]
Overview
This dataset contains the data of the three databases "Deutsch-Französische Kunstvermittlung 1870-1940, Paris", "Deutsch-Französische Kunstvermittlung 1870-1940/44, Berlin" and "Deutsch-Französische Kunstvermittlung 1945-1960, Paris" as Spreadsheets and a JSON-document as well as a platform to display the data.
The data was gathered and entered into former databases between 1999 and 2005. In 2019 the data was migrated to a MySQL-database and in 2021 the MySQL-database was exchanged by Elasticsearch.
Research data
The data was gathered and entered into three former databases between 1999 and 2005 and in the realm of two research projects. Both projects were carried out by the DFK Paris in cooperation with the Kunsthistorisches Institut, Freie Universität Berlin. The principal Investigator of both projects was Thomas W. Gaehtgens.
From 2021 to 2022 the data has been semantically enriched and the presentation on the website has been redesigned. These measurements were part of a project led by Anne Klammt.
Software
In general, this platform allows the integration of that data into web based systems such as content management systems. To be independent of the target technology, the integration is implemented with a set of customized HTML tags with no assumptions on lower layers. An API-only web application retrieves the data from an Elasticsearch instance and relays to the widgets.
A README in this dataset serves as documentation. It aims to provide information on:
the requirements to run the application
how to set up the API-application
importing the data from the included json documents
importing the additional image databuilding the javascript integration asset
how to integrate the widgets on a third-party page
Requirements
linux (not a requirement but the howto in documentation assumes linux)
elasticsearch (2.2.3)
ruby (2.2.5)
nodejs (4.4.4), only for building
(2022-06-06
Neural Dependency Parser with Biaffine Attention and BERT Embeddings
This resource contains the code of the dependency parser used in the paper: Do and Rehbein (2020). "Parsers Know Best: German PP Attachment Revisited".
The parser is a re-implementation of the neural dependency parser from Dozat and Manning (2017) and is extended to use the BERT language model as input features.
The pre-trained models on the German dataset of the SPMRL 2014 Shared Task used to report results in the paper are also included.</p
Codices Palatini latini – Historische und philosophische Handschriften
Here you can find the descriptions of the Latin Palatine manuscripts as published in the manuscripts catalog "Die historischen und philosophischen Handschriften der Codices Palatini Latini in der Vatikanischen Bibliothek (Cod. Pal. lat. 921-1078)", edited by Dorothea Walz, Wiesbaden 1999 (Kataloge der Universitätsbibliothek Heidelberg 3). The description for each manuscript was subsequently recorded as TEI-XML file by XML encoding in accordance with TEI-P5 using GND standard vocabulary.These TEI files follow an outdated TEI schema originally developed at the Herzog August Bibliothek Wolfenbüttel and contain some ad hoc solutions which were chosen pragmatically in Heidelberg and which do not always comply with the TEI Guidelines. A future migration of the dataset into a fully TEI-compliant format is considered as desirable
14C-based ΔffCO2 estimates for Heidelberg and OPE and input data for the Rhine Valley ffCO2 inversion (2019-2020)
These data files show the Δ14CO2, CO2 and CO measurements as well as the 14C-based ΔffCO2 estimates of the flask samples collected in Heidelberg (HEI, 2019-2020) and at the ICOS site Observatoire pérenne de l'environnement (OPE, Sep. 2020 - Mar. 2021). Moreover, modelled ΔffCO2 and ΔCO concentrations based on the Stochastic Time-Inverted Lagrangian Transport (STILT) model and the Netherlands Organization for Applied Scientific Research (TNO) emissions are given for the respective flask hours. These data are used to compare flask-based with inventory-based ΔCO/ΔffCO2 ratios (Maier et al., 2023a).
For Heidelberg, also ΔCO-based ΔffCO2 estimates are presented for the afternoon hours in 2019 and 2020. The afternoon 14C- and ΔCO-based ΔffCO2 estimates from Heidelberg are used as observational constraint in the ffCO2 inversion performed in the Rhine Valley (Maier et al., 2023b)