Advanced Emergency Medicine (E-Journal)
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A Retrospective Study on the Timing of Perioperative Antimicrobial Interventions in Class I Incisions
Get PDF This retrospective case-control study was conducted to provide reference for the timing of antimicrobial drug use for clinical prevention. Cases of patients with type I incision surgery of 2019 at a 3A hospital were selected for statistical analysis, and 336 cases each with surgical duration ≥3h and equivalent surgical duration <3h of the same type were selected as the case and control groups, respectively. The focus was on the type of surgery, length of surgery, timing of medication, days of medication, and the occurrence or not of surgical site infection (SSI)in patients. There was a significant difference in the incidence of SSI between the case and control groups (18.15% Vs. 6.15%, P<0.001). The number of cases of intraoperative additional antimicrobial drugs for surgical duration ≥3h was 155 (57.83%), of which the number of cases with SSI was 40 and the number of cases with SSI without additional 113 was 21 (25.81% Vs. 18.58%, P=0.145). Additional intraoperative antimicrobial drugs for surgery ≥3 h were not effective in reducing the incidence of SSI, but significantly reduced the number of days patients were hospitalized. The occurrence of SSI is related to many factors and should not be overly dependent on the use of antimicrobial drugs
Current Situation of TCM Treatment of Schizophrenia
Get PDFSchizophrenia is a common clinical disease in the department of psychiatry. Traditional Chinese medicine treatment of schizophrenia has a long history, rich experience, small side effects, to a certain extent can alleviate the condition of patients with schizophrenia. This article reviews the current situation of TCM treatment of schizophrenia in recent years from three aspects: TCM treatment, acupuncture treatment and catgut embedding treatment
Research progress of insulin resistance in alcoholic liver disease
Get PDFAlcoholic liver disease (ALD) is a liver disease caused by long-term heavydrinking, but its pathogenesis is relatively complex, among which Insulin resistance(IR) is closely related to the formation of ALD. In this paper, the epidemiological status of ALD at home and abroad and the research progress of insulin resistance in alcoholic liver werereviewed from the relationship between ALD and IR
Development of NCOVID-19 Colloidal Gold Immunochromatographic Test Strip
Get PDFPurpose: To establish a fast, simple and accurate method and immunoassay test card for the detection of new coronavirus (nCOVID-19) antigen. Methods: In this study, colloidal gold immunochromatography technology was used to detect nCOVID-19 virus antigens through the sandwich method. At the same time, the preparation plan of colloidal gold was improved, and the application of rapid immune-diagnosis technology in other fields was developed. In this study, purified recombinant nCOVID-19 nucleocapsid protein is used as the antigen to prepare murine monoclonal antibodies. The BN02 antibody produced by the mouse is used as the detection antibody to couple with colloidal gold, forming a gold-labeled complex probe. BN9m1 is used as the coating antibody for the C-line, and ProA is used for the T-line. The polymerization of colloidal gold particles enables us to detect the new coronavirus antigen’s appearance. Thus an in vitro rapid detection kit for virus detection can be made. Results: The positive detection rate of the antigen quality control serum with this colloidal gold reagent was 100%. The specificity was 100%, and the sensitivity was 1ng/ml. Conclusion: The nCOVID-19 antigen detection reagent (colloidal gold method) developed in this research has high specificity and sensitivity, and can be used in conjunction with nucleic acid detection. As a means of detecting nCOVID-19, it can achieve qualitative and rapid screening of samples with advantage such as accuracy, repeatability, and low cost
Relationship between Ambulatory Pulse Pressure, Pulse Pressure Index and Coronary Artery Disease in Patients with Hypertension
Get PDFObjective: To analyze the relationship between ambulatory pulse pressure, pulse pressure index, and coronary artery disease in patients with hypertension. Methods: From February 2018 to February 2019, a group of 100 patients with hypertension (control group) and a group of 100 patients with hypertension and coronary artery disease (experimental group) were selected to monitor and analyze dynamic pulse pressure and pulse pressure indicators. Results: In terms of clinical indicators, values of NPPI, 24hPP and 24hPPI in the experimental group were significantly higher than those in the control group. P < 0.05 indicates that there is statistical value in the data difference. Conclusion: In the clinical diagnosis of hypertension patients, ambulatory pulse pressure, pulse pressure index are highly correlated with the risk of coronary artery disease. Therefore, researchers should actively pay attention to the relevant indicators of patients to lay a solid foundation for the effective protection of patients’ health
To use wild resources properly: a lesson from two species of human coronaviruses
Get PDFThe global pandemic of COVID-19, a disease caused by a severe acute respiratory syndrome-related coronavirus (SARSr-CoV), is responsible for over a hundred million confirmed cases and more than two hundred deaths worldwide. Accumulating evidence indicates correlations between the abuse of wild resources and the outbreaks. To reduce the risks of getting infected with human coronaviruses (HCoVs), brief introductions to HCoVs were made, the hosts of them are listed, the probable transmission routes of the SARSr-CoVs and MERS-CoVs are analyzed, and the recommendation that we use wild resources properly was put forward
A Clinical Observation and Study on Prunella Vulgaris Decoction in Promoting the Repair of Chronic Infective Refractory Wounds
Get PDFObjective: To further study the clinical efficacy of prunella vulgaris decoction in promoting the repair of chronic infective refractory wounds, and analyze and evaluate the feasibility of this treatment. Methods: A total of 80 patients with chronic infective refractory wounds were screened out from a hospital from March 2020 to March 2021. The random sampling method was used to divide the patients into the experimental group and reference group. The experimental group was treated with prunella vulgaris decoction while the reference group was treated with routine wound dressing change. Wound repair rate, bacterial negative conversion rate, healing time and clinical comprehensive efficacy in the two groups were used as evaluation indexes in this study. Results: After different treatment, the conditions of the patients in the two groups were statistically analyzed. It was found that the wound repair rate, bacterial negative conversion rate and total effective rate of the experimental group were much higher than that of the reference group. In addition, the wound healing time in the experimental group was also significantly shortened compared with that of the reference group. Conclusion: Prunella vulgaris decoction bears obvious anti-inflammatory and anti-bacterial effects and can accelerate the speed of wound repair, which has great practical value in clinic treatment and prosperous prospect in future development and application
Research Progress on the Relevance between Intestinal Flora and Colorectal Cancer
Get PDFCancer is a common chronic disease all over the world, which will cause serious health burden. At present, the debate about the role of intestinal flora in the prevention and control of cancer has always existed. Therefore, researchers should pay close attention to the impact of intestinal flora on several cancers (such as colon cancer, liver cancer and breast cancer). In addition, it is reported that intestinal flora may also affect the efficacy of cancer chemotherapy and immunotherapy. This paper introduces some energy research results to help clear the relationship between intestinal flora and cancer, even cancer micro environment. It can help clarify the mist of cancer and gut microbiota, let those little creatures to serve the progress of improving mankind living condition and of health and medicine
Establishing Zhaoqing Medical Service System to Build the Guangdong, Hong Kong, and Macao Health Community
Get PDFThe construction of the Guangdong, Hong Kong, and Macao health community is not only an inherent requirement for the economic development and social progress of the Pearl River Delta region, but also an inevitable requirement for the realization of the healthy China strategy and the internationalization and modernization of medical and health care in the three cities. This article discusses answers to issues related to the Guangdong, Hong Kong, and Macao health community. It takes the construction of Zhaoqing medical service system in Guangdong Province as an entry point
Construction of Clinical Biobanks and the Medical Ethics
Get PDFNowadays, various types and forms of clinical biobanks have been gradually established worldwide, which have become one of the important components and research platforms of life science and related disease researches in the medical system. This article mainly introduces the construction, management and operation of clinical biobanks, and discusses the medical ethics faced by it