Advanced Emergency Medicine (E-Journal)
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Research Progress on the Correlation between Metabolic Syndrome and Benign Prostatic Hyperplasia
Get PDFMetabolic syndrome is a group of clinical manifestations of metabolic abnormalities, which is closely related to the occurrence
of various diseases and has become an important field in modern medical research. With the change of lifestyle, the incidence of metabolic
syndrome has been increasing year by year. Research shows that its components, including obesity, insulin resistance, hypertension and dyslipidemia, may have a potential correlation with benign prostatic hyperplasia (BPH). Benign prostatic hyperplasia is a common male urinary
system disease, and its occurrence mechanism is complex, involving multiple endocrine and metabolic pathways. Existing research has
gradually revealed the role of the components of metabolic syndrome in the development of prostate hyperplasia, especially in aspects such
as inflammatory response, changes in hormone levels and cell proliferation. However, although there have been preliminary research results,
the specific mechanism between metabolic syndrome and prostate hyperplasia still needs to be further explored. Therefore, this review aims
to systematically analyze the relationship between metabolic syndrome and its components and prostate hyperplasia, summarize the relevant
mechanisms, and summarize the current research progress and future research directions, in order to provide a reference for clinical prevention and treatment
Current Study of Daily Life Influences on Sarcopenia Under the Healthy China Initiative
Get PDFThe prevention and management of sarcopenia among the elderly are now a pivotal topic for healthy aging, in light of the Healthy
China strategy’s comprehensive advancement and the escalating demographic aging.Aging correlates with an increased prevalence of sarcopenia, a degenerative skeletal muscle condition.Data from a 2023 epidemiological study show that 5% of Chinese community-dwelling elderly aged 60 and above suffer from sarcopenia.7% to 23.9%.This condition substantially diminishes the elderly’s quality of life and impairs
their functional autonomy, concurrently elevating risks for falls, disability, and all-cause mortality.This paper delves into the factors affecting
sarcopenia in the elderly in everyday life, and appraises the existing prevention and therapeutic measures.The study’s analysis of interventions’ effectiveness and limitations forms a theoretical foundation for sarcopenia management in the elderly
Study on Mesenchymal Stem Cell Therapy for Female Premature Ovarian Failure
Get PDFPremature Ovarian Failure (POF) refers to ovarian dysfunction occurring in women before the age of 40, characterized by amenorrhea, infertility, and hypoestrogenic symptoms, which severely impairs patients’ reproductive health and quality of life. Traditional treatments
such as Hormone Replacement Therapy (HRT) can only alleviate symptoms but cannot reverse ovarian function decline. Mesenchymal Stem
Cells (MSCs) have emerged as a research hotspot in regenerative therapy for POF due to their multipotent differentiation potential, immunomodulatory properties, and paracrine characteristics. This article systematically reviews the biological characteristics of MSCs derived from
bone marrow, umbilical cord, adipose tissue, and menstrual blood, and deeply explores their core mechanisms in repairing ovarian function, including inhibiting cell apoptosis, regulating the immune microenvironment, promoting angiogenesis, and exerting paracrine effects.
It further analyzes the efficacy differences of various transplantation routes in clinical applications and existing challenges, and prospects
breakthrough directions in technologies such as biomaterial-combined transplantation and gene editing. This review provides a theoretical
reference for basic research and clinical translation of MSCs-based therapy for POF
Huoxue Quscar granules combined with erbium-doped fiber laser therapeutic instrument in the treatment Clinical application of atrophic scars in acne
Get PDFObjective: To compare the clinical efficacy and safety of Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument and Huoxue-Quscar granules alone in the treatment of atrophic acne scars. Methods: A total of 350 patients with atrophic
acne scars treated in our hospital were randomly divided into an experimental group and a control group. The patients in the experimental
group were treated with Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument, and the patients in the control group were treated with Huoxue-Quscar granules. The effective rate and incidence of adverse reactions were compared between the two
groups. Results: The effective rate of the trial group was 97.14%, which was significantly higher than 92.00% of the control group (P < 0.05).
The incidence of adverse events in the experimental group (0.57%) was lower than that in the control group (4.00%) (P < 0.05).Conclusions:
Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument has good efficacy and safety in the treatment of
atrophic acne scars
Research progress on dexmedetomidine-assisted clinical treatment of intracranial aneurysms
Get PDFThis study comprehensively analyzes the application and clinical progress of dexmedetomidine in the treatment of intracranial
aneurysms. Intracranial aneurysms have become an important challenge in the field of neurosurgery due to their risk of rupture and high
mortality rate. In this context, the use of dexmedetomidine is particularly important, especially in perioperative management to maintain
hemodynamic stability and provide effective sedation. A review of research shows that dexmedetomidine, due to its α2-adrenoceptor agonist properties, can effectively reduce intraoperative blood pressure and heart rate fluctuations, reduce changes in intracranial pressure, and
reduce the risk of aneurysm rupture. Furthermore, it shows potential advantages in reducing postoperative complications and accelerating
recovery. However, its suitability in specific patient groups and safety of long-term use still require further study. In the Discussion section,
we highlight the advantages of dexmedetomidine, such as stable sedation and subtle effects on the cardiovascular system, while pointing out
the limitations and challenges of its use in specific patient populations. Future research should focus on determining the optimal clinical use
of dexmedetomidine, including dosage, timing of administration, and suitability for specific patient populations. Taken together, dexmedetomidine has shown obvious advantages in perioperative management of intracranial aneurysm surgery, but its optimal application method and
long-term safety still require more clinical research support. This study provides important reference information for future clinical practice
and provides a scientific basis for further optimizing treatment strategies for patients with intracranial aneurysms
Efficacy of budesonide combined with cefoperazone sodium and sulbactam sodium in the treatment of neonatal pneumonia and its influence on serum inflammatory factors
Get PDFTo analyze the efficacy of budesonide combined with cefoperazone sodium and sulbactam sodium in neonatal pneumonia, and observe its effect on serum inflammatory indicators. 96 patients with neonatal pneumonia admitted to our hospital from January 2023 to January
2024 were selected as the research objects, and they were divided into a control group and an observation group using random number table
method, with 48 cases in each group. The control group was treated with speridone and sulbactam, and the observation group was treated
with budesonide on the basis of the control group. The clinical efficacy, lung function indicators [peak volume ratio (VPEF/VE), peak expiratory flow (TPEF/TE)], and serum inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6), matrix metalloproteinase 9 (MMP-
9) and leukotriene B4 (LTB4)] levels were compared between the two groups. Compared the clinical efficacy of the two groups, the levels of
VPEF/VE, TPEF/TE and PEF in the observation group were higher than those in the control group (
Research progress in dental bonding technology
Get PDFDentin bonding is a core technique in oral clinical practice. It seals the dentin tubules through mechanical interlocking and chemical bonding, isolates external stimuli, enhances retention, reduces microleakage, decreases postoperative sensitivity, and the risk of secondary
caries, while dispersing stress to protect the pulp. It serves as the foundation for the success of modern dental restoration. This article provides a review of the mechanisms and influencing factors of dentin bonding, as well as methods to improve bonding performance. It discusses the latest research progress in dentin bonding in recent years, aiming to provide references for the development of more durable and stable
dentin bonding materials and techniques
Analysis of the related factors of deep vein thrombosis after gynecological tumor surgery
Get PDFObjective To investigate the risk factors of deep vein thrombosis (DVT) in patients after gynecological tumor surgery. Methods
From March 2014 to March 2024, 57 patients with deep vein thrombosis after surgical treatment in the Department of Oncology and gynecology of our hospital were selected as the research sample, and were included in the observation group. In addition, 55 patients without deep
vein thrombosis after gynecological tumor surgery were included in the control group. The clinical data of the patients were collected, and
the related factors of postoperative deep vein thrombosis were analyzed. Results Univariate analysis showed that age, BMI, operation time,
operation range, hypertension and diabetes, platelet count, benign and malignant tumor, preoperative fluid infusion were related to the occurrence of postoperative deep vein thrombosis (P 40 years, BMI>25 kg/m2, malignant
tumor, hypertension and diabetes, platelet count > 300×109/L were independent risk factors for postoperative DVT, while preoperative fluid
infusion was a protective factor for postoperative DVT. Conclusion Age, BMI, malignant tumor, combined cardiovascular technology and
platelet count are related to the occurrence of deep vein thrombosis after gynecological tumor surgery, and no preoperative fluid infusion is a
protective factor
Comparison of the efficacy of vitrectomy combined with different filling procedures in the treatment of rhegmatogenous retinal detachment of macular detachment
Get PDFBackground and purpose: To compare the clinical efficacy of vitrectomy combined with silicone oil tamponade and perfluoropropane (C3F8) tamponade in the treatment of macular hole retinal detachment(MHRD).Methods: The clinical data of 55 patients with MHRD
who were treated in our hospital from January 2022 to January 2023 were retrospectively analyzed,They were divided into silicone oil group
(n=25) and C3F8 group (n=30) according to the surgical methos. The differences in macular hole closure, retinal detachment and replacement, vision recovery and postoperative complications between the two groups were compared.Result: Three months after surgery, there was
no significant difference in the macular hole closure rate between the C3F8 group and the silicone oil group (P>0.05),There was no significant difference in retinal reattachment rate between C3F8 group and silicone oil group (P>0.05),the best corrected visual acuity after surgery
was significantly improved in both the C3F8 group and the silicone oil group, and the C3F8 group was better than the silicone oil group
(P0.05).
Conclusion: Vitrectomy combined with intraocular tamponade for MHRD can effectively reposition retina and close macular holesImprove
the patient’s best corrected visual acuity, and the vision recovery in the C3F8 group was better than that in the silicone oil group
Analysis of therapeutic effect of extracorporeal shock wave on tennis elbow
Get PDFExtracorporeal shock wave therapy plays an important role in the prevention and treatment of musculoskeletal diseases due to its
advantages of convenient operation, safety, high efficiency and no drug intervention. In recent years, extracorporeal shock wave therapy has
been widely used in the treatment of external humeral epicondylitis, such as through extracorporeal shock wave combined with ultrashort
wave therapy and other physical factors. As people become more accepting of exercise, the frequency of some musculoskeletal disorders is
also increasing. For such diseases, the effect of drug treatment is often reflected in the alleviation of symptoms, and the radical cure of the
disease is not obvious. Under this premise, the advantages of the physical factor therapy approach appear. By performing extracorporeal
shock wave therapy, the pain can be relieved in a short period of time, and the patient’s normal activities and symptoms can be significantly
improved after the treatment cycle