Advanced Emergency Medicine (E-Journal)
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To Explore the Brain-Gut Interaction Pathway of Intestinal Flora Based on Traditional Chinese and Western Medicine
Get PDFTo Explore the Brain-Gut Interaction Pathway of Intestinal Flora Based on Traditional Chinese and Western Medicin
A Case of Combining Coronary Angiography and CT Angiography to Diagnose an Acute ST Segment Elevation Myocardial Infarction and a Single Coronary Artery
Get PDFCoronary artery anomalies encompass a wide spectrum of clinical presentations and pathophysiological mechanisms, exhibiting signifcant heterogeneity. The majority of coronary artery anomalies exhibit negligible clinical manifestations.. Among these anomalies, the occurrence of a single left coronary artery with congenital right coronary artery agenesis represents an exceedingly rare manifestation. This case report presents the clinical profle of a 37-year-old male patient who underwent intervention and coronary CT to confrm his acute myocardial infarction and a solitary left coronary artery. Athorough understanding of coronary variations and the identifcation of coronary lesions can enable cardiovascular physicians to adopt more personalized treatment strategies for their patients
Application of Single Hole Laparoscopic Technique in Gynecological Accessory Surgery
Get PDFObjective: To explore the application of single hole laparoscopic technique in gynecological accessory surgery. Methods: From January 2021 to December 2022, 30 patients in the hospital department who applied single hole laparoscopic appendage surgery were se-lected for the experiment. Thirty patients were divided into the control group and the observation group, with 15 patients in each group. The patients in the control group were treated with conventional three hole laparoscopic surgery, and the patients in the observation group were treated with single hole Laparoscopy. The relevant indicators of patients in the two experimental groups during the operation and the scores of postoperative recovery were compared. Result: After the experiment, it was found that the sample removal time of the observation group patients was signifcantly faster than that of the control group. The pain score of the observation group patients at 24 hours after surgery was signifcantly lower than that of the control group, and the incision beauty score of the patients at 14 days after surgery was higher than that of the control group, with a statistically signifcant diference (
Based on the Theory of Chronic Liver Disease
Get PDFDoctors discuss the treatment of chronic liver disease from the perspective of dampness, poison, and blood stasis, less from the perspective of spleen Yin loss. The author discusses the physiological function of spleen Yin and its relationship with chronic liver disease, and analyzes that spleen Yin defciency is an important cause of chronic liver disease, and also an important manifestation of chronic liver disease, and puts forward three methods of solid spleen, liver and spleen treatment, sweet and fat tonic, sour and sweet Yin
Case Report: Pneumocystis Pneumonia Following Liver Transplantation Identified by High-Throughput Second-Generation Gene Sequencing Technology
Get PDFPneumocystis, a fungus species, has emerged as one of the predominant infectious pathogens in immunocompromised patients, particularly in liver transplant recipients who require immunosuppressants. The pathogen colonizes the recipient’s lower respiratory tract and induces a pulmonary infection. Respiratory failure is one of the leading causes of mortality in organ transplant recipients, as the disease pro-gresses swiftly, its diagnosis is difcult, and it is simple for it to occur. This report details the case of a patient admitted to Calmette Hospital, afliated with Kunming Medical University, diagnosed with pneumocystis pulmonary infection post liver transplantation. The diagnosis and successful treatment of the patient were facilitated by high-throughput second-generation gene sequencing technology based on metagenom-ics, enlightening future clinical diagnoses and treatments
CIC Rearrangement Sarcoma: A Case Report and Literature Review
Get PDFBackground: CIC-rearranged sarcoma (capicua transcriptional repressor- rearranged sarcoma, CRS) is a rare type of undifferentiated small round-cell sarcoma. There are few reported cases of CRS; in 2017, 115 cases were reported abroad and 10 cases were reported in China. Case summary: The patient is a 41-year-old male who presented with a mass in the left lumbar region for more than 1 month. Tumor excision was performed at another hospital. Pathology results indicated CRS. PET-CT indicated changes in the left lumbar region, and postoperative tissue repair changes were considered. However, combined with the medical history and imaging features, the clinical diagnosis was considered recurrence of tumor in the left lumbar region. Postoperatively, the patient was transferred to the burn department for pedicled skin-flap repair. Conclusion: CRS is rare, and the prognosis of these patients is poor. Surgical resection of the lesion is the first choice for patients without metastasis
Monitoring the Immune Response to Coronaviruses in SARS-CoV-2 Exposed and Vaccinated Individual
Get PDFIdentifying factors associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure and immunity is critical for quantifying mass immunity and preventing future pandemics. The current SARS-CoV-2 vaccine was losing efficacy in the face of new variants, and it is urgent to seek a broad coronavirus vaccine. We conducted a cross-sectional serosurvey of patients in Scotland from September 2021 to April 2022. The indirect enzyme-linked immunosorbent assay (ELISA) against 2135 patient serum samples showed monthly infection and vaccination rates from 24.71%-72.00% and 28.00%-61.50%. We showed that people over 65 receive higher priority vaccination, and 65–74-year-old female patients exhibited higher vaccination rates and lower probability of infection. In addition, we investigated cross-reactive antibodies of SARS-CoV-2 negative, infected, and vaccinated samples against the seasonal human coronavirus (sHCoV) spike (S) protein by ELISA. We found a 1.2-1.4-fold increase in antibody reactivity among sHCoV-229E, NL63, and OC43 against vaccinated donors compared to negative donors. These findings provided insights into exposure patterns in Scotland and support the feasibility of developing a broad coronavirus vaccine
Research progress of MicroRNA in podocytes autophagy in diabetic nephropathy
Get PDFDiabetic nephropathy (DN) is one of the most common microvascular complications of diabetes, and is a kind of abnormal microangiopathy of kidney structure, function or clinical indicators caused by diabetes. Podocyte injury has been considered as a major contributor to the progression of diabetic nephropathy(DN). microRNA can participate in podocytes injury through autophagy.In this paper, the mechanism of microRNA involved in DN podocytes autophagy was reviewed to provide reference for the treatment of DN in the future
Diagnosis of Dementia and Alzheimer's Disease Based on Classification Algorithms
Get PDFAlzheimer's disease is currently the most common kind of senile dementia. With the increasing aging degree of the global society, Alzheimer's disease will become an unavoidable social problem in an aging society. In order to improve this situation, artificial intelligence algorithms that are good at mining the internal laws of data are applied in the hope of more effectively diagnose this disease, which should be intervened as early as possible. After briefly restating the current situation of dementia and Alzheimer's disease, the diagnostic model for dementia is built using logistic regression, which achieves great accuracy despite the simplicity of the model. Then, two diagnostic models that can identify if the patient with dementia has Alzheimer's disease based on SVM and Random Forest are tested. Although both the algorithms perform poorly because of the sample imbalance, after processing the original data with SMOTE, their performances are largely improved
Effect of Doxorubicin Combined with Ipratropium Bromide on Pulmonary Function Indexes in the Treatment of Chronic Obstructive Pulmonary Disease
Get PDFObjective: To observe the effect of different methods in the treatment of chronic obstructive pulmonary (COPD) disease. Methods: 86 COPD patients attending the clinic from 2020.7 to 2022.11 were divided into groups I and II according to the envelope method, 43 cases each were treated with theophylline extended-release tablets and group II was treated with ipratropium bromide, the lung function indexes of each group were tested and the total effective rate was calculated and compared between groups. Results: At the end of the treatment course, FEV1, FVC and FEV1/FVC levels in group II were higher than those in group I, and the difference reached a significant level (P < 0.05). The total effective rate in group I was 74.42%, which was lower than that in group II, which was 95.35%, forming a significant difference (P < 0.05). Conclusion: Treatment with doxorubicin combined with ipratropium bromide for those with COPD is effective and worthy of popular application