155199 research outputs found
Sort by
Treatment and lifestyle change recommendations by cardiologist for patients attending cardiology outpatient clinics: a TLC study
No full textIntroduction: Just as it is important to recommend lifestyle changes such as exercise, diet and smoking cessation to patients in the low-medium-risk group for protection from cardiovascular diseases, it is also important to identify patients in the high-risk group and reduce cardiovascular risk with lifestyle changes and, when necessary, pharmacological treatment. Aim: This study evaluated the treatment and lifestyle change recommendations given by cardiologists to patients. Material and methods: Our study was shared with cardiologists via e-mail from January 2024 to February 2024, and the surveys were answered online. Our questionnaire, consisting of 30 questions, covers topics related to cardiovascular protection, diet, nutritional habits, lifestyle, and diagnosis and treatment strategies of coronary artery disease, heart failure, arrhythmia, and dyslipidemia. Results: Of the 104 participants included in the analysis, 37 (35.58%) were female, and 67 (64.42%) were male. The proportion of participants who recommended regular exercise to all of their patients was low at 25 (24.04%). It was determined that 60 (57.69%) participants were recommended to use aspirin in primary prevention in patients with moderate-severe cardiovascular risk. Achieving the target LDL value remains at a very low rate (2.88%). Conclusions: The rate of recommending lifestyle changes, diet and exercise to patients in cardiology outpatient clinics is very low. SGLT2 inhibitors (SGLT2i) and angiotensin receptor-neprilysin inhibitors (ARNI) have become highly regarded drugs in heart failure patients. The rate of achieving the target low-density lipoprotein cholesterol value in patients admitted to the cardiology outpatient clinic remains very low
A WABL-Based Two-Dimensional Representative of Fuzzy Numbers
No full textDefuzzification methods have an important place in fuzzy logic and fuzzy set theory. There are various defuzzification methods in the literature, such as Center of Gravity (COG), Mean of the Maxima (MOM), Bisector of Area (BOA), Weighted Average Based on Levels (WABL), etc. Normally, the defuzzified value of a fuzzy number gives the average numerical representative of this fuzzy number according to the membership degrees of components. However, the WABL operator, which is a more universal defuzzification operator, carries more information within itself. In this study, the defuzzified value of the fuzzy number is discussed within the framework of a two-dimensional plane. This approach includes information about the defuzzified numerical representative as well as the quality of this representative. New concepts of WABL Area Representative (WABL_AR) and Area Center of Gravity (ACOG) are proposed for fuzzy numbers. The properties of these concepts have been examined theoretically and suitable theorems for triangular fuzzy numbers have been proven. A numerical example is given for calculating the WABL_AR and ACOG values
Spearman dependence function-based goodness-of-fit test for the gene's relation
No full textA gene network represents the relationship between different groups of genes with various functions, aiming to depict how genes collaborate and influence each other’s activities within a biological system. This relationship can be effectively explained using copulas. Therefore, it is crucial to determine which copula best fits the gene data and provide the most accurate explanation of the relationships between gene groups. In this study, our objective is to introduce a Spearman dependence function-based goodness-of-fit test using Bernstein polynomial approximation. We apply this test to identify a copula model that can effectively explain the relationships between gene groups. A Monte Carlo simulation study is conducted to assess the performance of the proposed test. Next, we analyse histone gene groups using data from yeast cell regulation, as provided by Eisen et al. (1998). Specifically, we investigate the dependence model structures of gene interactions for eight histone genes
Linguistics and Translation
No full textA Short Cultural History of the English Language traces the evolutionof English through the lens of cultural history. Drawing on Vico’s theory ofsocietal stages and Sapir’s assertion that language shapes social reality, thischapter highlights how cultural shifts, worldviews, and social upheavals influencelinguistic development. It underscores the profound connection between languageand the societal context from which it emerges, providing a broad perspectivethat enriches the reader’s understanding of the topics to come.</p
Design and prototype production of a new external fixator pin that can dampen movement to reduce pin tract inflammation
No full textBackground: External fixation is a commonly used method in fixation of bone fractures. In this method, bones are positioned and secured by pins of the external fixator system. Although the system provides a reliable solution for fixing the fracture site, the most common problem in clinical practice of this method is pin site failure due to pin micro motions. This problem leads to the loosening of the pins which results in infection at the pin-bone interface that's called pin tract inflammation. The aim of this study is to reduce pin motions by altering the design of conventional Schanz pin so, a new pin, called Micro-Motion Damping Pin (MDP). Methods: MDP was compared with the Schanz pin in two methods. The first method compared inter-pin motion behaviors on a same external fixator bar that was set on polyethylene rods. The second method compared bending behaviors. A universal axial test machine was used to apply force in the experiments, and a non-contact video extensometer was used to capture inter-pin motions between the first and the third pins on the proximal fragment. Results: Although, the results showed that there was not a statistically significant differences between two pin designs in reducing the inter-pin motions (p = 0,240), the measured displacement of the MDP was less than the Schanz pin when compared. Displacements were 0,117 ± 0,02mm and 0,142 ± 0,065mm for the MDP and the Schanz pins respectively. Conclusion: The results point out the MDP absorbed some amount of the inter-pin motion when compared to Schanz pins. Moreover, the MDP's mechanical results were superior in bending tests, and the difference was statistically significant (p = 0,002). In conclusion, the new pin can be used in an external fixation treatment, since its mechanical features are as good as the Schanz pin, however it should be evaluated on human cadaver subjects in future studies
60+ Tazelenme Üniversitesi Öğrencilerinin Çevresel Risk Algısı ve Eko-Anksiyete (İklim Değişikliği Anksiyetesi) Düzeylerinin Belirlenmesi: Antalya Örneği
No full textThe Effect of Different Mixing and Compaction Temperatures on the Particle (Cantabro) Loss in Porous Asphalt Pavements
No full textExperimental Investigation of the Effect of Seawater on Glass and Carbon Fiber Composites via Mechanical Characterization
No full textSince composite materials are light and corrosion-resistant, they have replaced many traditional materials in the aviation and marine industries. Composite materials have the advantages of a much higher strength-weight ratio, lower maintenance requirements, and the ability to form complex shapes, such as bodies, compared to carbon steel. In this study, the mechanical properties of glass fiber reinforced (GFRP) and carbon fiber reinforced (CFRP) composite materials were investigated in marine applications in which composite materials had been used. In this study, 0/90 oriented twill weave eight-ply GFRP and eight-ply CFRP composite materials were used, incorporating the hand lay-up method and hot-pressing method. Seawater was taken from the Aegean Sea, Izmir Province (Bal & ccedil;ova/& Idot;nciralt & imath;), and had an average temperature of 22.43 degrees C. This seawater was kept in different containers for 30 days and 60 days (a total of 1440 h of keeping in seawater) with the intent to test the GFRP and CFRP composite samples separately. The produced CFRP and GFRP sheets were then cut with a wet (circular) saw in accordance with the standard procedure in the Composite Research and Testing Laboratory of the Dokuz Eylul University Department of Mechanical Engineering. Moisture retention percentages and Charpy impact tests were carried out. Then, three-point bending tests were carried out according to TS EN ISO 14125. The damage in the material was examined using a ZEISS Stereo Discovery.V12 imaging microscope (Oberkochen, Germany). The mechanical properties of CFRP- and GFRP-reinforced composite samples before and after aging were investigated using the Charpy impact test and three-point bending test. Then, the effects of the seawater environment on the mechanical properties of the CFRP and GFRP composite materials were evaluated by comparing the results. The aim was to better understand what kind of damage would occur in GFRP and CFRP composite materials given the effects of seawater and at what stages changes would occur in the mechanical properties of these materials. Moisture retention rates (%) in the tested samples after the Charpy impact test were 2.56% in GFRP and 0.47% in CFRP after 30 days. In the tested samples after the three-point bending test, these values were 1.41% in GFRP and 0.31% in CFRP after 30 days. Subsequent to the Charpy impact tests, the fracture toughness values of the CFRP samples tested at the 30 J impact energy level before aging in seawater conditions for 30 days or 60 days were found to be increased by 15.79% and 21.08%, respectively. The fracture toughness values of the GFRP tested at the 30 J impact energy level in dry conditions and kept in seawater for 30 days or 60 days were found to be 27.69% and 29.23%, respectively. The energy absorbed during the impact tests by the GFRP samples was higher than in the CFRP samples. This showed that the GFRP samples were more brittle. Subsequent to the three-point bending tests, the CFRP composite samples kept in seawater for periods of 30 days and 60 days showed changes in the modulus of elasticity of 7.48% and 7.46%, respectively, compared to the dry samples. The GFRP composite samples kept in seawater for periods of 30 days and 60 days showed changes in the modulus of elasticity of 7.015% and 11.53%, respectively, compared to the dry samples. The change in the modulus of elasticity was less in the CFRP samples than in GFRP. All of these results showed that the mechanical properties of CFRP were better than those of GFRP