Universidad Internacional del Ecuador
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Effects on Mechanical and Physical Properties of Ta Element Addition to Ti-6Al-7Nb Alloy
No full textTi and its alloys play a leading role in biomedical applications within the field of materials science. In this study, different amounts of Ta were added to the TiAlNb alloy. Various analyses were carried out to determine the physical and chemical properties of the produced samples. DSC (differential scanning calorimetry), and XRD (X-ray diffraction) analyses were conducted to determine the phase transformations and crystal structure of the alloys, respectively. SEM-EDX (scanning electron microscopy) and OM (optical microscopy) images were taken to analyze the chemical structure of the samples and to examine their microstructures in more detail. Microhardness and wear resistance tests were performed to determine some mechanical properties of the produced samples. It was observed that increasing the tantalum content increased both hardness and wear resistance. These findings suggest that the addition of tantalum to the Ti-6Al-7Nb alloy could be an effective strategy to improve biomaterial performance
2020 Sonrası Güney Kafkasya’da Değişen Jeopolitik Düzen: Azerbaycan-Gürcistan İlişkileri
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Determination of economic sustainability factors in sheep husbandry enterprises through validity and reliability analysis
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Crestal Bone Level Changes in Periodontally Healthy Patients Under Supportive Care: A 4-Year Retrospective Study
No full textIntroduction: Crestal bone level (CBL) changes following implant placement may result from both physiological and pathological processes. Although early marginal bone remodeling is generally regarded as a physiological response, its progression must be carefully monitored. Identifying long-term risk factors is essential for preserving peri-implant bone stability. This study aims to assess changes in CBL and crestal bone remodeling (CBR) over a 4-year period in periodontally healthy patients undergoing regular supportive care. Materials and Methods: This retrospective study included 97 patients with a total of 142 implants who received implant-supported restorations and consistently attended supportive maintenance therapy. Patients with a history of periodontitis were excluded. Radiographic evaluation was conducted at four time points: T0 (implant placement), T1 (prosthetic loading), T2 (1 year after loading), and T3 (4 years after loading). CBL and CBR were assessed using calibrated digital measurements. The effects of systemic, surgical, site-related, and prosthetic variables on CBL and CBR were analyzed using linear regression and Pearson correlation tests. Results: Smoking was the only consistent predictor of increased CBL loss across all intervals (p < 0.001). In the early phases (T1–T0, T2–T1), subcrestal placement was associated with significantly less bone loss (p ≤ 0.003). In the late phase (T3–T2), implant diameter became a significant predictor (p = 0.002). Prosthetic factors were not significant in the overall analysis. However, within the subcrestal subgroup, screw-retained prostheses, platform-switched connections, and anterior placement were associated with reduced CBR during specific intervals. Strong correlations were observed between CBL changes across all intervals, indicating progressive and cumulative bone dynamics. Conclusion: The primary factor for initial bone stability is the depth of implant placement, whereas long-term results are mainly affected by implant geometry and prosthetic design. Smoking continues to be a significant, modifiable risk factor. These insights emphasize the importance of individualized treatment plans and maintenance strategies to ensure long-term implant success
Evaluation of the Efficacy of Tenofovir Alafenamide in Patients with Low-Level Viremia Under Chronic Hepatitis B Treatment
No full textIn this multicenter, retrospective study involving 62 patients, we investigated whether switching from entecavir (ETV) or tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) represents a superior treatment strategy for patients with chronic hepatitis B (CHB) experiencing low-level viremia (LLV). The study determined that TAF significantly improved both virological and biochemical outcomes. At 48 weeks, the complete virological response (CVR) rate was 77.8% for those who switched from ETV and 81.8% for those who switched from TDF, with Hepatitis B virus deoxyribonucleic acid (HBV DNA) negativity reaching 81% by month 12. Additionally, significant normalization of liver enzymes, albumin, and platelet counts was observed across the cohort. While the switch from TDF was associated with a significant increase in triglycerides and high-density lipoprotein (HDL) and a decrease in estimated glomerular filtration rate (eGFR), no such changes were detected in the ETV group. This evidence suggests that TAF provides robust virological control in LLV patients and is associated with favorable biochemical improvements. However, due to the study's limitations, the strong assertion that TAF promotes the regression of liver fibrosis and reduces the risk of hepatocellular carcinoma (HCC) must be interpreted with caution
Humanity and Culture in the Digital Age: Science and Art Center Teachers' Views on the Social Impacts of Science Education
No full textThe aim of this research is to examine the views of Science and Art Education Center teachers on the social effects of science education. This study aims to analyze the social role of science education in detail by examining the multidimensional effects of digitalization on humanity and culture from sociological and pedagogical perspectives. In the study, the social effects of science education in the process of digital transformation are discussed in the context of Sociotechnical Systems Theory, the Scientific Literacy Framework, and Social Constructionism Theory. In this context, the effects of digital transformation on students, teachers, and society through science education were evaluated from a qualitative perspective. This study is a qualitative research designed with a phenomenological approach that aims to examine the views of Science and Art Center teachers on the social effects of science education in the digital transformation process. A semi-structured interview form was used as the data collection tool. The analysis process of the study was carried out within the framework of Sociotechnical Systems Theory, the Scientific Literacy Framework, and Social Constructionism Theory. QSR NVivo-11 software was used to analyze the data. The data obtained were analyzed using the content analysis method. The findings show that science education makes significant contributions to developing individuals' worldviews, sensitizing them to social problems, and integrating them with cultural values in the digital age. However, some pedagogical and cultural challenges faced by science education in the digital transformation process were also identified. In line with the results of the research, it is suggested that curricula, teacher training programs, and digital content should be restructured to increase the potential of science education to produce social benefits