Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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    Stanya-Shodhana Mahakashaya - A Potential Solution for Diseases in Breast Feeding Infants - A Review

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    Breast milk is referred as Stanya in Ayurveda texts also known as Piyush (nectar/Amrita); justifies totally with its importance for a newborn. Newborns primarily rely on the breast milk for their nutrition. Ayurvedic texts have described qualities of normal breast milk under the heading “Shuddha Stanya”. Emphasis has been given on the aspect of abnormalities of breast milk and their consequences on infants and as well as on mothers in Ayurveda classics. Vitiation in the normal qualities of Stanya is described as Stanya Dushti. To deal with the same, a concept of Stanyashodhan is mentioned in Charak Samhita in the form of group of ten drugs known as Stanyashodhan Mahakashaya. This article involves synthesizing information from various Ayurvedic texts and internet databases like PubMed, PubMed Central Databases, Google Scholar, CrossRef to substantiate the Stanya Shodhan attributes of these herbs. Neonates are highly susceptible to medication errors and adverse drug events due to their fragile physiology, immature organ systems, and limited ability to metabolize and eliminate medications. This problem can be solved if we treat the mother and thus providing treatment to infants through the Shodhita breast milk using Stanyashodhana Mahakashaya

    Ayurvedic approach in the management of ALS (MND) - A Case Study

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    Amyotrophic Lateral Sclerosis (ALS) is progressive motor neuron disease (MND) in which nuclei of upper & motor neurons in spinal cord, cranial nerve & motor cortex are involved. ALS also known as Lou Gehrig’s Disease. The illness is relentlessly progressive in nature, leading to death by respiratory paralysis. There is an incidence of 1-3 per100000 & a prevalence of 3-5 per 100000. It exhibits muscle weakness, Fasciculation, Dysphagia, etc. leads to the complications as involvement of pyramidal signs. This disease affects normal rhythm of life ultimately results in the limitations of day-to-day routine. In this case study 50 years old male patient had symptoms of weakness in Lower extremities, Dysphagia, unable to stand without support, slurred speech. He diagnosed with Amyotrophic Lateral Sclerosis in 2022 at SSKM Hospital, Kolkata, West Bengal. He took treatment in various hospitals of Kolkata but he didn’t get any relief. Then he came to our institute in the hope of proper management. The term ALS is not mentioned in our Samhita however we can clinically correlate the sign & symptoms of this disease with Avritta (~Occlusion) Pakshaghat (~Paralysis). After 3 months of treatment, patient was assessed clinically & with the help of ALSFRS -R Score. Before treatment it was 10 which was increased to 30, showing significant improvement also noticed in his various activities

    Ayurvedic Management of Shwitra (Vitiligo) - A Case Study

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    Skin is the outer most covering of the body and is the largest organ of integumentary system. In human being, skin pigmentation (affected by melanin) varies among population and skin type can range from dry to non-dry and from oily to non-oily. In Ayurveda Bhrajak Pitta is responsible for Prabha. Any impairment in Bhrajak Pitta and Vata cause skin diseases. All skin diseases come under Kushta and Shwitra is one of them. Like other types of Kushta, Shwitra is caused due to vitiation of Tridoshas and Dhatus like Ras, Rakta, Mamsa and Meda.[1] In Modern system of medicine similar disease is described as Vitiligo. Vitiligo is a chronic auto immune disorder that causes white lesions on skin. This happens when melanocytes are destroyed causing the skin to turn milky white colour

    Female Development Across Ages: An Ayurvedic Review with Contemporary Correlations

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    Background: The age classification system employed in Ayurveda for females offers a methodical way to comprehend physical, physiological, and social transitions across life stages. Texts such as the Charaka Samhita, Harita Samhita, and Parasara Smṛti categorise female development according to mental maturity, reproductive milestones, and dosha predominance. Aim and Objectives: This study focuses on the Ayurvedic classification of female age and contrasts it with contemporary developmental models, such as Erikson\u27s psychosocial phases, Freud\u27s psychosexual theory and Tanner\u27s puberty classification. The goal is to integrate contemporary and traditional perspectives to provide a holistic understanding of female development. Methods: This study methodically gathers information from traditional Ayurvedic texts, peer-reviewed scientific publications, contemporary textbooks, and reliable websites. Selection is based on authenticity, relevance, and credibility, while extraction involves theme categorization and interpretation. For an in-depth analysis, the synthesis integrates modern scientific insights with ancient Ayurvedic wisdom. Results: Ayurvedic classifications align with contemporary models, indicating that while there are universal patterns of growth and maturity, there are also variations brought about by genetic, environmental, and cultural influences. Discussion & Conclusion: A comprehensive, preventative approach to female health is provided by Ayurvedic classification. By combining Ayurvedic and contemporary frameworks, a holistic model for lifetime well-being can be fostered to improve disease prevention, reproductive management, and personalized healthcare

    A Study Protocol for Pharmaceutico-Analytical study of Rajat Sindoor and evaluation of its Anti-Cancer Activity against Leukaemia using HL60 and K562 cell line model

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    Introduction: Leukaemia is a disease of haematological malignancies that result from the abnormal multiplication of developing leukocytes. A patient suffering through leukaemia experiences an aberrant blood cell synthesis, usually involving leukocytes (white blood cells). Leukaemia is categorized into two groups, based on the cell types that are mostly involved: Lymphoid and Myeloid, also based on the disease\u27s natural course: Acute and Chronic. Neoplasms and Vyadhi Arbuda, which is mentioned in the classics of Ayurveda (Charaka Samhita and Sushruta Samhita), are comparable. Rasa Aushadhis have many therapeutic advantages in many chronic health aspects such as CKD, Cardiac conditions, Inflammatory conditions, bleeding disorders, cancers, etc. Rajat Sindoor is one of the effective Rasa Kalpas found no previous work on in-vitro investigation to assess the anti-cancer activity w. s. r. to Leukaemia. Materials and Methods: Rajat Sindoor will be prepared as per classical reference. The prepared formulation will be assessed with organoleptic characters and physio-chemical parameters. The Experimental study will be carried out according to the OECD guidelines. Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The experimental study and statistical analysis will be done accordingly. Discussion: The purpose of the current study is to evaluate Anti-cancer activity of Rajat Sindoor w. s. r. Leukaemia using HL60 and K562 cell line model. A small step to fill the research gap in the treatment aspect of Leukaemia from Ayurvedic point of view will be done. If significant positive results are obtained in this work, then it will be a valuable contribution in the treatment of leukaemia

    A case study highlighting the impact of Brahmi (Bacopa monnieri (Linn.) Pennell.) Panchanga Churna in the management of Pandu Roga

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    Introduction: Pandu is characterized mainly by Vaivarnya of body with other Lakshanas like Agnimandya, Daurbalya, Angamarda etc. and can be correlated to Anaemia in contemporary medicine. In the present study the patient is a 26-year-old female who presented with symptoms like Pandutwa in Anana Netra Nakha (Pallor of face, sclera and nails), Hritspandanam (palpitation), Dourbalya (general weakness), Hata Anala (diminished digestive power), Bhrama (giddiness) and hair fall. Brahmi (Bacopa monnieri (Linn.) Pennell.) is an important drug of Ayurveda classical texts and Indian Materia medica and well known as a Medya and Rasayana, is taken to evaluate its clinical efficacy in the management of Pandu Roga. Objective: To evaluate the efficacy of Brahmi (Bacopa monnieri (Linn.) Pennell.) Panchanga Churna in the management of Pandu Roga. Materials and Methods: The study was conducted on a woman of 26 years, for a period of 120 days. 5g of Brahmi Panchanga Churna was given twice daily. No specific diet change was instructed during the course of treatment. Clinical symptoms and hematological parameters were documented before, during and after treatment. Results: After using Brahmi Panchanga Churna, 5 g twice daily for 120 days, without any specific change in diet habit, a noticeable improvement in symptoms is seen and Hb% is enhanced from 9 g/dL to 11 g/dL. Conclusion: The results suggest that Brahmi (Bacopa monnieri (Linn.) Pennell.) Panchanga Churna is significantly effective in the management of Pandu Roga

    A comparative study of the effect of Kati Basti and Kati Pichu with Astakatvar Taila in the management of Gridhrasi w.s.r. to Sciatica

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    Gridhrasi, commonly equated with Sciatica in modern medical terminology, is a debilitating condition characterized by radiating pain along the course of the sciatic nerve. Ayurveda describes Gridhrasi as a disorder predominantly caused by vitiation of Vata Dosha, often accompanied by Kapha, resulting in pain, stiffness, and restricted mobility. The condition derives its name from the characteristic limping gait of affected individuals, resembling a vulture (Gridhra). Modern medical science attributes Sciatica to nerve root compression or irritation, frequently due to herniated discs, spinal stenosis, or degenerative changes in the lumbar spine. Though technological advancements have improved diagnostics and treatment modalities, the chronic and recurrent nature of Sciatica necessitates a holistic management approach. Ayurveda offers a unique perspective through Panchakarma therapies, Shamana Chikitsa (palliative care), and lifestyle modifications. The integration of Ayurvedic practices with contemporary medical interventions has demonstrated promising results, warranting further exploration of their combined efficacy. This review article aims to provide a comprehensive analysis of Gridhrasi, examining its etiology, pathophysiology, and therapeutic approaches from both Ayurvedic and modern perspectives. By analyzing classical references alongside current evidence, this work endeavors to underscore the relevance and effectiveness of traditional practices in addressing this persistent clinical challenge. The study specifically focuses on the Ayurvedic classification, underlying pathophysiology, and etiological factors of Gridhrasi, contributing to a deeper understanding of its holistic management

    The clinical aspect of Dhatu

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    The main components of human body are - Dosha, Dhatu and Mala. Dhatus facilitate movement, nourish the blood, and provide muscle cover for overall strength, flexibility, and smooth functioning of the body. Ayurveda has considered Jara or Vardhakya as a natural and inevitable process as well as a Swabhavajavyadhi (Natural disease). The study of the difficulties of animal ageing, particularly human ageing and old age, is referred to as geriatric (Gerontology) and geriatric (Geriatrics). Every substance in the world, both inanimate and alive, is ancient and ageing. Proper diet, exercise and lifestyle can create a balance among these three subtle essences, ensuring long life. In Ayurveda there are so many diet and regimen which can stabilized the condition of aging. By adopting some healthy lifestyle we can balance the state of Dhatus in the aging. As there are 7 Dhatus in the body, we can give different therapeutic procedure to enhance the Dhatus

    Effect of Trikatvadi Gudika along with Gokshura Kwatha in the management of Benign Prostatic Hyperplasia: A Case Report

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    Benign Prostatic Hyperplasia (BPH), a common non-cancerous enlargement of the prostate gland, is characterized by the proliferation of its cellular components. It is the most prevalent benign tumor in men, and its management ranges from conservative approaches to surgical interventions. In Ayurveda, BPH shares clinical resemblance with conditions described under Mutraghata, particularly Mutragranthi and Vatashteela. Ayurvedic texts detail numerous formulations for Mutraghata, including the administration of Trikatvadi Gudika along with Gokshura Kwatha, as recommended in the Mutrakrichradhikara of Bhavaprakasha. This case report details the clinical presentation and management of a 71-year-old male patient who reported increased frequency and urgency of micturition, weak urinary stream, and sensation of incomplete bladder emptying persisting for two years. Diagnostic evaluation revealed an enlarged prostate. Prostate Specific Antigen (PSA) levels were within normal range. The patient was treated with Trikatvadi Gudika (1.5 g) mixed with honey, administered along with 48 ml of Gokshura Kwatha twice daily before meals for a duration of 30 days. Significant symptomatic relief was observed after treatment. The International Prostate Symptom Score (IPSS) showed marked reduction across all parameters. Objective assessments revealed a reduction in prostate size and a decrease in post-void residual urine. Ayurvedic management may thus offer a valuable complementary or alternative option for patients with Benign Prostatic Hyperplasia, especially in geriatric populations who are at higher risk for complications from conventional surgical interventions

    Clinical efficacy of Marichadi Churna and Karviradya Taila Nasya in the management of Nasarsha (Nasal Polyposis)

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    Nasal polyps are non-cancerous, chronic inflammatory growths of the nasal mucosa that significantly impact quality of life through symptoms such as nasal obstruction, discharge, anosmia, and recurrent infections. Modern management often includes corticosteroids or surgical excision, but high recurrence rates and associated side effects necessitate safer, long-term alternatives. In Ayurveda, a comparable condition known as Nasarsha is primarily attributed to Vata-Kaphaja Dosha vitiation and is managed through internal medication and local therapies aimed at Doshic balance and mucosal cleansing. This clinical study evaluated the efficacy of Marichadi Churna (oral) and Karviradya Taila Nasya (nasal application) in 24 patients with uncomplicated nasal polyposis, divided into three groups - each receiving individual or combined therapies for 30 days. Symptom severity and radiological findings were assessed before and after treatment. The results demonstrated statistically significant improvements in all groups. Nasal obstruction, discharge and sense of smell, with combination therapy showing slightly enhanced outcomes. Radiological improvements, particularly in maxillary sinuses, were also more pronounced in the combination group, though intergroup differences were not statistically significant. The study supports the use of these Ayurvedic formulations as effective, non-invasive, and well-tolerated options for managing Nasarsha and nasal polyposis

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