Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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Pharmacological review of Darvyadi Kashaya in the management of Prameha and Diabetes Mellitus
No full textDiabetes Mellitus (DM), a global metabolic disorder, is characterized by chronic hyperglycemia due to insulin resistance or deficiency. Ayurveda correlates this condition with Prameha. Darvyadi Kashaya, a classical Ayurvedic polyherbal formulation mentioned in Charaka Samhita, has traditionally been used in the management of Prameha. It comprises potent herbs like Daruharidra (Berberis aristata), Devadaru (Cedrus deodara), Vibhitaki (Terminalia bellirica), Haritaki (Terminalia chebula), Amalaki (Emblica officinalis), and Mustaka (Cyperus rotundus), each known for their Kapha-Pitta Shamaka, Medohara, Deepana, and Pramehaghna actions. This review integrates Ayurvedic textual references and modern pharmacological evidence to evaluate the antidiabetic potential of Darvyadi Kashaya
The Ayurvedic concept of Ama and its role in Rheumatic Diseases
No full textAma refers to the improperly digested Annarasa (nutritional essence), It is a toxic, undigested metabolic waste that accumulates in the body and is considered the root cause of many diseases, particularly those originating in the Amasaya (stomach). In Ayurveda, Agni is one of the most vital transformative principles, and its impairment (Agnimandya) leads to the formation of Ama, which in turn is seen as the foundation of numerous disorders. Rheumatic diseases are chronic disorders that primarily affect the joints, muscles, bones, ligaments, and sometimes internal organs. They can be autoimmune or inflammatory and cause symptoms such as pain, stiffness, swelling, and reduced mobility. WHO cited, these conditions include rheumatoid arthritis (RA), osteoarthritis (OA), gout, systemic sclerosis, systemic lupus erythematosus (SLE), ankylosing spondylitis, and psoriatic arthritis. These diseases significantly impact quality of life, leading to disability and decreased productivity. From an Ayurvedic perspective, nearly all diseases, including rheumatic conditions, are rooted in Ama. Preventive and management strategies focus on eliminating or preventing the formation of Ama. This involves Hetuparivarjan (avoiding causative factors), adopting Dinacharya (daily regimen), and undergoing Rasayana Chikitsa (rejuvenation therapy). The use of Deepan-Pachan Dravyas (appetizers), Vata-Shamak Aushadhis (Vata-pacifying medicines), and regular Yogic practices further support detoxification and balance. Although modern medicine provides effective therapies for rheumatic diseases, side effects often reduce their long-term utility. Ayurveda offers a holistic approach by addressing the root cause (Ama) and supporting the body’s natural healing. This article is a simple attempt to understand Rheumatic disease in Ayurvedic perspective and explore the Ayurvedic perspective on Rheumatic disease through an analysis of its causative factors(ama), pathology, clinical features and prognosis
Pharmaceutical and Analytical Study of Rasanjanadi Churna
No full textIntroduction: Ulcerative Colitis is an idiopathic form of acute and chronic ulcero-inflammatory colitis affecting chiefly the mucosa and submucosa of the rectum and descending colon. The signs and symptoms of Ulcerative Colitis show much resemblance with the symptoms of Raktatisaar. Therefore, an Ayurvedic herbal formulation namely Rasanjanadi Churna mentioned in Yogratnakar Atisaar Adhyaya Raktatisaar Adhikaar was chosen for study. The present research focuses on Pharmaceutical and Analytical study of Rasanjanadi Churna.
Materials and Method: Pharmaceutical study comprised of preparation of Rasanjan and preparation of Rasanjanadi Churna. Analytical Study includes Organoleptic and Physico-chemical analysis (Moisture content, Total Ash %, Acid insoluble Ash %, Water soluble extractive value, Alcohol soluble extractive value, pH, TLC) of raw materials and Rasanjanadi Churna.
Observations and Results: Rasanjanadi Churna was light brown in colour, bitter in taste and had a characteristic smell. Physico-chemical analysis revealed Moisture content - 9.938%, Total ash% - 5.991 %, Acid insoluble ash - 0.349 %, Alcohol soluble extractive% - 28.542 %, Water soluble extractive% - 29.44 %, pH - 5.17, TLC - 0.86 RF value.
Discussion: All the raw materials showed analytical values well within API limits. Rasanjanadi Churna has low AIA which indicated its purity. It is almost equally soluble in water as well as alcohol. It is acidic in nature.
Conclusion: Method of Preparation of Rasanjanadi Churna mentioned Yogratnakar - Raktatisaar Adhikaar is feasible and economical
Resolution of a Chronic Non-Healing Ulcer Using Ayurvedic Treatment - A Case Study
No full textThe management of non-healing ulcers (Dushta Vrana) presents a significant clinical challenge. Non-healing ulcers are a common problem in the present era, often resulting from trauma or pathological insults, leading to prolonged suffering for patients. Despite the efficacy of contemporary medicine in treating infected wounds with antibiotics, the issue of non-healing wounds remains unresolved. Ayurveda offers a holistic approach that plays a crucial role in the management of Dushta Vrana. In the first part of his compendium, Sushruta extensively discusses wound healing and its classifications under the Vranitopasaniya Adhyaya. Ayurveda describes various compound formulations and oils for both oral administration and topical application to promote wound healing. In this case, a 56-year-old male patient presented with a non-healing ulcer on the medial aspect of the left foot, posing significant challenges in wound management. The ulcer had been treated with modern medications, but persistent infection complicated the recovery process. Incidentally, routine biochemical testing revealed previously undiagnosed hyperglycemia, which was likely a contributing factor to the impaired wound healing. The integration of Manjishtha (Rubia cordifolia), Lodhra (Symplocos racemosa Roxb.), and other internal medications, Yashada Bhasma along with the external application of Kampillakadi oil and regular cleansing with Pancavalkala Kvatha, proved to be an effective therapeutic strategy for managing this non-healing wound. The comprehensive approach led to part of wound healing within 35 days, highlighting the potential benefits of combining traditional Ayurvedic treatments with modern wound care practice
Management of Bell’s Palsy (Ardita) through Panchakarma - A Case Report
No full textBell\u27s palsy condition involving a rapid and unilateral onset of peripheral paresis/paralysis of the seventh cranial nerve, resulting total facial paralysis. It affects 11.5-53.3 per 100,000 individuals a year across different populations. Exact etiology of Bell\u27s palsy is unclear. As a result of inflammation of the facial nerve, blocking the transmission of neural signals or damaging the nerve. The condition normally gets better by itself within 6. In Ayurveda, Bell’s Palsy can be correlated with Ardita. Ardita is one of the Vaata Vyadhi among 80 Nanatmaj Vaata Vyadhi, it cause contracture of face, nose, eyebrow, forehead, and mandible get crooked. Here, the case presented is of a 50 yr old male patient come with complain of weakness and deviation of, inability to close an eye lid with lacrimation, drooling of saliva, difficulty to eating and drinking, pain in left upper and lower limb, face and behind the left ear, in episodic nature 2 time per week since august 2023 and its become persist in February 2024. Patient was treated with Virechana Karma, Dashmoola Taila Nasya for 7 days and Karna Purana with Dashmoola Taila for 21 days. There was noticeable improvement in physical findings and significant improvement in House Brackmann Grading for facial palsy after treatment
Tears of Shiva: A Key to Medical Miracles
No full textElaeocarpus ganitrus, commonly known as Rudraksha, holds immense significance in Sanatana Dharma and has been known for centuries for its spiritual and medicinal properties. This cohort study primarily focuses on the pharmacological activity of Rudraksha, its Ayurvedic perspective, and its formulations, while also giving a gist of its religious significance. The article highlights key experiments conducted on Rudraksha, detailing their procedures and results, exploring the therapeutic potential of its compounds. This article paves the way for future studies for research into its efficacy in treating various challenging ailments that are often difficult to address with conventional treatments
A Case Study on the efficacy of Ayurvedic drugs in treating Kidney Stones
No full textKidney stones also known as nephrolithiasis, is a common disorder characterized by the formation of mineral and salt deposits within the kidneys. These deposits or stones, can cause significant pain and discomfort as they travel through the urinary tract. While many stones pass on their own, some require medical intervention. Kidney stones resemble the description of Ashmari in Ayurveda and due to its dreadful nature, Ashmari is included in Astamahagadha[1] and it is regarded as a grave disease simulating death.[2] The present case study is of a 19-year-old female patient having symptoms of back pain radiating from the loin to the groin region, burning micturition, pain during and after micturition, nausea, and vomiting. The clinical diagnosis made based on the symptoms as Ashmari (kidney stone). Patient was put on Samshamani drugs (Varanadi Ghrita, Punarnava Asava, etc) for period of one month along with Pathya Apathya. After Ayurvedic medication, the patient was relieved from all the symptoms and that was evident on investigations as well. This piece of work aims to study the effect and potency of ayurvedic drugs on kidney stones of small size (4-6mm), in a short period of time and impeding them from going through minimally invasive procedures
Diagnosis and Management in Yakrita Vikara
No full textYakrita Vikara refers to the various structural and functional disorders of the Yakrita (liver), which holds a central position in Ayurveda as the Mula Sthana of Raktavaha Srotas. This study aims to explore the differential diagnosis and management of Yakrita Vikara based on Ayurvedic principles. Disorders like Kamala, Pandu, Raktapitta, Jalodara, Madatyaya and Yakritodara are studied in correlation with diagnostic tools described in Ashtavidha Pariksha - including Nadi, Mala, Mutra, Jihwa, Sparsha, Shabda, Drika and Akriti - to aid in clinical differentiation. The pathogenesis involves Mandagni, Ama formation, Srotorodha and Doshadushya Sammurchana, ultimately leading to liver pathology. References from authoritative Ayurvedic texts such as Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya and Bhavaprakasha provide insight into the classical understanding of these disorders. Treatments focus on restoring Agni and eliminating Ama, using single drugs like Bhumyamalaki, Punarnava, Haritaki, and classical formulations such as Punarnava Mandura, Lohasava, Triphala Kwatha, and Guduchi Swarasa. This paper emphasizes the importance of accurate diagnosis through Ayurvedic examination and a holistic approach in the management of Yakrita Vikara. Understanding the interrelation between Rasa, Rakta and Pitta as Dushyas and applying individualized therapy, enhances treatment outcomes and reaffirms the relevance of traditional methods in managing hepatic disorders
A Literature Review on Bahiparimarjana Chikitsa in Nidranasha
No full textAlong with Aahar (diet) and Brahmacharya (balanced conduct), Nidra (sleep) is one of the three essential pillars of a healthy life, in accordance with the Trayopasthambha. The quality and quantity of sleep have a profound influence on both emotional and physical well-being, such as happiness, Nourishment, immunity, and fertility. Improper sleep can even prove fatal. In the present era of modernisation, people often encounter lifestyle changes that have significantly impacted sleep patterns, which can lead to Nidranasha (Insomnia), typically triggered by anxiety, stress, irregular work hours, excessive screen time, and a poor daily routine. From an Ayurvedic perspective, this condition can cause Vata Vriddhi (aggravation of Vata Dosha) and Kapha Kashaya (depletion of Kapha Dosha). This disturbs the natural balance required for the maintenance of sleep. Ayurveda offers a holistic approach to managing insomnia through a combination of therapies. Different Ayurvedic text includes Anthaparimarjana, Bahiparimarjana, and Satvavajaya chikitsa to treat insomnia. Bahiparimarjana Chikitsa is crucial for managing various health conditions by cleansing, healing, and alleviating pain through localized and generalized treatment. External therapy such as Abhyanga, Padabhyanga, Uastadana, Lepan, Tarpana, Murdha Tail, and Savahanam. An integrative Ayurvedic approach reduces the root cause of Nidranasha and promotes overall health and well-being
Rare Diseases through the Lens of Ayurveda: Principles, Paradigms, and Prospects for Integrative Care
No full textRare diseases are defined in contemporary biomedical science primarily on the basis of prevalence and population impact, with significant clinical, social, and policy implications. India\u27s National Policy for Rare Diseases (2021) follows global standards in highlighting the unique challenges posed by rare disorders. Ayurveda, as an ancient system of life sciences, does not employ statistical rarity as a basis for disease classification. Instead, Ayurveda interprets conditions including rare, genetic, and congenital ailments through theoretical constructs such as Doṣa-Dhātu-Mala, the Pañca Mahābhūta, Sādhyāsādhyatā (prognosis), and the principle of Anukta Vyādhi (unnamed diseases). This manuscript explores rare diseases from the Ayurvedic perspective, offering a detailed examination of primary principles, diagnostic and therapeutic frameworks, and their contemporary relevance. By mapping classical Ayurvedic doctrines to modern nosology and genomics, this paper argues for integrative models in rare disease care, highlighting challenges and avenues for future research