Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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Clinical Efficacy of Amlapittanashaka Yoga over Avipattikara Churna in the Management of Urdhwaga Amlapitta with special reference to Hyperacidity
No full textAmlapitta is a Pitta Pradhana Vyadhi, caused by an increase in the Amlaguna of Pachaka Pitta. The symptoms of Amlapitta are as same as Hyperacidity or Gastritis or Hyperchlorhydria where increased level Hydrochloric acid in the stomach. It is commonly affected in middle aged persons because of their lifestyle. It is the most common disease in digestive disorder. Hence in this study an attempt is made to evaluate the efficacy of Amlapittanashaka Yoga over Avipattikara Churna in the management of Urdwaga Amlapitta. Objectives: 1) To evaluate the individual efficacy of Amlapittanashaka Yoga in the Management of Urdwaga Amlapitta. To compare the efficacy of Amlapittanashaka Yoga and Avipattikara Churna in the Management of Urdwaga Amlapitta. Method: 60 patients of Urdwaga Amlapitta, fulfilling the diagnostic criteria were taken for the study and divided into 2 groups consisting 30 patients each. Amlapittanashaka Yoga and Avipattikara Churna are given 5gm BD dose with Sukoshna Jala in Adhobhaktakala as the Shamana Aushadhi for 28 days in both sexes in the age group of 20-60 years. Weekly follow up is done and at 8th Week. Results: The overall effect of the treatment showed significant results in both the groups. There were no patients who did not respond to the treatment. And there were no complications observed during the treatment schedule. Treatment is effective in Urdwaga Amlapitta disease
Efficacy and Safety of Guggulu Tablet in Obesity and Rheumatic Disease Activity: An Open-Label, Single-Arm Clinical Trial
No full textBackground: Obesity and arthritis are major global health burdens, often coexisting and compounding morbidity through mechanical stress and systemic inflammation. Ayurveda describes Medoroga (obesity) and Sandhivata (arthritis) as conditions responsive to Guggulu (Commiphora wightii), a resin with lipid-lowering and anti-inflammatory properties. This study evaluated Guggulu tablets in adults with obesity and rheumatic disease activity.
Methods: An open-label, single-arm, pre–post clinical trial was conducted at a rheumatology and obesity clinic in Pune, India. Forty participants (mean age 46.8 ± 9.5 years; 65% female; mean BMI 30.0 ± 2.8 kg/m²) with rheumatoid arthritis or osteoarthritis received purified Guggulu tablets (500 mg, twice daily) for 24 weeks. Primary endpoints included changes in body weight, BMI, waist circumference, and disease activity scores (DAS28, WOMAC, pain VAS). Secondary outcomes assessed inflammatory markers, metabolic parameters, lipid profile, and quality of life (HAQ DI).
Results: Thirty-six participants (90%) completed the study. Body weight decreased by −4.3 kg, BMI by −1.6 units, and waist circumference by −5.0 cm (all p<0.001). DAS28 declined by −1.2 points, with 61% achieving MCID. WOMAC pain and function improved by −17.9 and −14.8 points, respectively, while pain VAS decreased by −20.9 mm. CRP (−2.5 mg/L) and ESR (−9.1 mm/hr) reduced significantly. Metabolic improvements included reductions in fasting glucose (−6.0 mg/dL), HbA1c (−0.3%), HOMA-IR (−0.8), total cholesterol (−12.2 mg/dL), LDL (−9.5 mg/dL), and an increase in HDL (+3.1 mg/dL). HAQ DI improved by −0.4. No serious adverse events occurred.
Conclusion: Guggulu tablets produced clinically meaningful improvements in weight, metabolic parameters, inflammation, and arthritis-related outcomes, with good tolerability. These findings support Guggulu as a promising integrative intervention for obesity-associated rheumatic disease, warranting confirmation in larger randomized controlled trials
Therapeutic applications of Panchakarma in Autoimmune Disorders
No full textAutoimmune diseases arise when the immune system attacks the body\u27s own tissues, leading to a spectrum of organ-specific and systemic disorders. Conventional treatments focus on immunosuppression, which can compromise overall immunity. Ayurveda provides a holistic and individualized approach, with Panchakarma offering a potential therapeutic modality for autoimmune conditions. According to Ayurvedic principles, autoimmune diseases stem from Mandagni, Ama and Srotorodha often triggered by Viruddha Ahara. Panchakarma helps correct these imbalances through detoxification, restoration of Agni, and immune modulation. Therapies such as Vamana, Virechana, Basti, and Nasya are strategically employed based on the disease\u27s chronicity, Doshic involvement, and Rogi Bala. This article discusses disease-specific Panchakarma protocols for few autoimmune diseases. The integrative approach emphasizes Nidana Parivarjana, Ama Pachana, Rookshana and Shodhana, aiming to restore Dhatu Samya, delay the progression of disease and enhance long-term health. With growing evidence linking gut health, immune dysregulation, and oxidative stress to autoimmunity, Panchakarma presents a promising alternative to contemporary management strategies
Soumanasya in Women\u27s Mental Health: A Narrative Review of Preconceptional Care in Ayurveda
No full textThis narrative review explores the ancient Ayurvedic concept of "Soumanasya" (mental harmony) and its critical role in preconception care for women. Drawing from classical Ayurvedic texts, particularly Charaka Samhita, this review investigates how mental well-being influences fertility and conception outcomes. Recent studies indicate that 40-60% of individuals diagnosed with infertility experience severe anxiety and depression, underscoring the bidirectional relationship between mental health and reproductive function. By integrating classical Ayurvedic insights with modern scientific fields such as psychoneuroendocrinology, this review explores how Manasika Bhavas (mental states) influence hormonal balance, ovulatory function, implantation, and overall reproductive health. It advocates for a comprehensive approach to preconception care that gives equal importance to Soumanasya (mental harmony) and Sharirika Swasthya (physical well-being). The findings suggest that integrating Soumanasya-based approaches in the modern era preconception care may enhance reproductive success and offspring well-bein
A Dissection - Based Anatomical Correlation of Kukundara Marma In Light of Ayurvedic Principles: A Comprehensive Study
No full textKnowledge of Marma is considered equivalent to half the understanding of Shalyatantra. Even a minor injury to a Marma point can result in intense pain, deformity, or even death. Therefore, these vital points must always be managed with utmost caution and precision. Among the 107 Marmas, Kukundara Marma is categorized under the Prishthagata Marmas. Prishthagata Marmas are described as 14 in number. It is classified as Sandhi Marma, and is closely associated with sacroiliac joint. Trauma to Kukundara Marma results in loss of sensation and paraparesis of lower limb. It is situated on the outer side of the buttocks on the two sides of the vertebral column and 2 in number. This is classified as a Vaikalykara (deformity) Marma. There exists considerable variation among scholars in interpreting the exact anatomical structure and location of Kukundara Marma. Therefore, it becomes essential to clearly identify its precise anatomical basis, regional extent, and structural composition, as well as to assess its role and vulnerability in cases of injury. The susceptibility and anatomical-clinical importance of Kukundara Marma will be highlighted, once again validating the relevance of Sushruta’s ancient concept of Marma in modern times
Management of Spider Envenomation through Ayurveda - A Case Report
No full textSpider envenomation cases have been reported from many parts of India, especially in Kerala. In Agadatantra, it is referred to as Lutha Visha, and a detailed description of it, including different varieties of Lutha, signs and symptoms of envenomation and its effective management, are explained. A 10-year-old girl presented to the OPD with a history of spider envenomation, showing multiple vesicular lesions on the lateral aspect of her left neck, accompanied by pain, burning sensation, and erythema. Given the clear diagnosis of Lutha Visha, treatment commenced with Patolakaturohinyadi Kwatha tablet, Vishavilwadi Gulika internally and Kottamramachadi Choornam for topical application with milk. After three days, Lodhrasevyadi Kashaya was added to the prescribed medications internally. Following seven days of treatment, the vesicular lesions had almost healed, and the medications were modified to Gopichandanadi Gulika, Rajanyadi Choornam, internally and Kottamramachadi Choornam for Kshalana. At the final visit, two weeks later, all the above medications were discontinued, and Indukantha Ghritam was prescribed internally for one month as Rasayana. In this case, Lutha Visha was effectively managed using specific formulations mentioned in Ayurveda classics and Keraleeya Visha Chikitsa
Ayurvedic Management of Switra (Vitiligo) - A Single Case Study
No full textVitiligo is a common autoimmune pigmentary disorder of great socio-medical importance. It is cauterized by white spots appeared on the skin due to melanocytes deficiency. Affects 0.5 -1% of the worldwide population, causing disfigurement and serious disturbances in quality of life. It can be correlated with Switra in ayurveda. Due to side effects and limitation of the contemporary science, some harmless and effective medicines are expected from alternative medical sciences. Ayurveda has great potential to treat such autoimmune diseases. The following case study of treating the condition of Switra with Shodhana and Shamana Chikitsa
Systematic Review of Balanites aegyptiaca (Ingudi): Phytochemistry, Pharmacology, and Therapeutic Potentials
No full textBalanites aegyptiaca (L.) Delile, commonly known as Ingudi or Desert Date, is a highly valued medicinal tree traditionally used in Ayurveda, Unani, and African folk medicine. Widely distributed in arid and semi-arid regions of Africa, the Middle East, and South Asia, it has been utilized for centuries for its nutritional and therapeutic benefits. Almost all parts of the plant, including fruits, seeds, bark, and roots, are reported to possess medicinal properties. B. aegyptiaca contains a wide range of bioactive compounds, including lipids, carbohydrates, proteins, organic acids, alkaloids, saponins, and flavonoids, which are largely responsible for its diverse pharmacological activities. Recent studies have highlighted its antioxidant, antibacterial, antifungal, wound healing, antiulcer, hepatoprotective, antidiabetic, and anticancer effects, attributed to these phytoconstituents. With growing scientific validation, B. aegyptiaca holds promise as a source of novel therapeutic agents. The present review aims to provide comprehensive information on its traditional uses, phytochemistry, and pharmacological potential, underscoring its importance as a multipurpose medicinal resource of tropical regions
Harnessing Ayurveda for Neurological Disorders: A Case Study on Joubert Syndrome
No full textJoubert syndrome is a rare genetic neurological autosomal recessive disorder characterized by abnormal development of the cerebellar and brainstem regions during foetal growth. It presents with a spectrum of symptoms, most commonly affecting muscle tone and coordination, breathing, eye movements, and sometimes speech.[1] The incidence of Joubert syndrome is approximately 1 in 100,000 live births globally.[2] While it is primarily caused by inherited genetic mutations, sporadic cases also occur. Currently, there is no definitive cure, and management focuses on supportive therapies such as physiotherapy and occupational therapy. In Ayurveda, Sharira Cheshta (bodily movements) is regulated by Vata Dosha.[3] Vitiation of Vata can result in impaired muscle tone, abnormal posture, dysfunctional eye movements, and speech difficulties. Based on this understanding, an Ayurveda treatment protocol was formulated to balance Vata and enhance the patient’s quality of life. Core therapies included Snehana (oleation), Swedana (sudation), and Basti Karma (medicated enemas), which are central to Vata Chikitsa. Given the progressive nature of the condition and its poor prognosis - Rasayana Chikitsa (rejuvenation therapy) was also integrated to promote systemic resilience, improve immunity, and delay disability. Although the disease has been present since birth and symptoms were noticed in later stage, it is attributed to an imbalance in the Vata dosha. This integrative approach aimed to provide symptomatic relief and improve the overall well-being of the affected child. In this study an 8 years old male child who was diagnosed with Joubert syndrome who was having complaints of altered gait and balance since 5 years associated with difficulty in framing sentences since 1 year was treated with Ayurveda treatment protocol
Panchagavya as a Prebiotic and Bioenhancer: Bridging Ayurveda and Microbiome Science
No full textBackground: Panchagavya a classical Ayurvedic formulation comprising five cow-derived substances milk, curd, ghee, cow urine and dung extract has been historically revered in Indian traditions for both spiritual and medicinal purposes. With emerging interest in the gut microbiome\u27s role in health and disease. Panchagavya is gaining renewed attention for its potential to influence digestive and systemic wellbeing.
Objective: To explore and interpret the role of Panchagavya in gut health through the lens of Ayurveda and modern biomedical science particularly focusing on its interaction with the gut microbiota, intestinal epithelial function and the gut-brain axis.
Methods: This review synthesizes classical Ayurvedic texts, contemporary scientific literature on the microbiome and recent experimental studies assessing the probiotic, antimicrobial, anti-inflammatory and bio enhancing properties of Panchagavya and its components.
Results: Panchagavya acts as a nutritional supplement and prebiotic, promoting the growth of short-chain fatty acid-producing bacteria like Bifidobacterium, which are essential for maintaining intestinal integrity and reducing inflammation. Its components, such as fermented milk and curd contribute to microbial balance. while cow’s urine demonstrates antibacterial and bio enhancing effects. Ghrita (ghee) shows mucosal-protective and healing properties. These actions collectively help in preventing leaky gut, modulating immune responses and potentially improving mental health via the gut-brain axis.
Conclusion: Panchagavya offers a unique integrative approach to digestive and systemic health by aligning Ayurvedic principles with modern microbiome research. While traditional use supports its efficacy, further clinical studies using modern methodologies are needed to confirm its safety, standardize its formulation and validate its therapeutic benefits across diverse health conditions