University of Las Palmas de Gran Canaria
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Understanding the role of food Neophobia in the willingness to consume functional rice
Understanding consumer preferences for new foods, such as functional rice, is crucial for developing varieties that meet consumer needs and promote health. Our research, incorporating a hybrid discrete choice model and psychometric data, reveals that food neophobia significantly contributes to hesitancy in consuming functional rice. Additionally, we found that being female, childless, and having lower levels of education and income are associated with higher levels of food neophobia. Based on a sample of 1666 Chinese respondents, these findings underscore the potential impact of functional rice on consumer health. The health benefits of functional rice strongly appeal to consumers, especially those with a good understanding of the concept, who engage in regular exercise, or who have health issues. In particular, respondents preferred micronutrient-enhanced rice to low GI and gluten varieties when comparing various health benefits. Notwithstanding, individuals who suffer from kidney disease show a strong preference for the low-gluten variety. A segment analysis confirms these results, indicating a preference for functional rice, particularly the micronutrient-enhanced variety, among diverse consumer segments. Finally, in general, educated, younger, and wealthier individuals are more likely to choose functional rice.1,1265,3Q1Q1SCIE11,
Ileal Predominance in Crohn’s Disease Is Associated with Increased Intestinal Surgery and Biological Therapy Use, with Lower Treatment Persistence
Introduction: Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location and therapeutic patterns.
Methods: We analyzed patients with CD diagnosed from January 2005 to May 2023 registered in the nationwide ENEIDA registry. A univariate Cox regression analysis assessed the association of disease location with biologic use and persistence (with treatment discontinuation as a failure event), as well as the use of intestinal resections. A multivariate model was constructed to evaluate the independent association of disease location with therapeutic patterns, controlling for potential confounders such as sex, age at inclusion and diagnosis, disease duration and behavior, previous surgery or biological therapy, extraintestinal manifestations, and perianal disease.
Results: The study included 17,292 patients with a median follow-up period of 6 years (interquartile range 2-10 years). Ileocolonic location was associated with a higher biologic use than colonic location (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.22-1.38) and ileal disease (HR 1.21, 95% CI 1.16-1.27), independently predicting biologic use (P < 0.001). Ileal location was associated with a lower biologic persistence than ileocolonic location (HR 1.14, 95% CI 1.07-1.21) and colonic disease (HR 1.10, 95% CI 1.01-1.20), independently predicting biologic persistence (P = 0.019). Ileal disease was associated with a higher likelihood of intestinal resections than colonic (HR 2.82, 95% CI 2.45-3.25) and ileocolonic location (HR 1.13, 95% CI 1.05-1.22), independently predicting the use of surgery (P < 0.001).
Discussion: CD location with ileal predominance is associated with a distinct therapeutic pattern, including higher biologic use, lower treatment persistence, and increased rates of intestinal resections.20319492,39110,2Q1Q1SCI
Isolation of a Novel Caprine Eimeria christenseni Strain (GC) in Canary Islands and Analysis of Parasitological, Clinical, and Pathological Findings on Experimentally Infected Goat Kids
Eimeria christenseni is considered among the most pathogenic Eimeria species in goats. The aim of this study was to isolate an E. christenseni strain and to assess its infectivity, pathogenicity, and ability to develop a protective immune response. After previous collection of E. christenseni-positive faeces, purification of oocysts, and amplification in donor animals, an experimental infection was carried out. A total of 19 kids were divided into three groups: primary-infected and challenged, challenge control, and uninfected control. Infections were performed orally with 2 × 105 sporulated oocysts per animal. Oocyst shedding, clinical signs, and production parameters, in addition to haematological and histopathological features, were monitored. The results showed that the Gran Canaria (GC) E. christenseni strain had similar morphological and biological characteristics to those previously described, but no significant clinical signs were observed despite the high oocyst counts here recorded. The novel strain isolated would therefore be of low pathogenicity but still able to develop significant immunoprotective responses upon challenge infections. Its biological similarities to highly pathogenic species such as Eimeria ninakohlyakimovae and Eimeria arloingi might enable comparative studies aimed at developing alternative strategies for drug treatments, including Eimeria species (strain)-specific vaccination strategies for the efficient control of goat coccidiosis.180,6983,0Q1Q1SCIE10,
Abbie Hoffman: Análisis de Steal This Book y su contexto en los años 60 en Estados Unidos.
Nightlife in Bologna through the analysis of statutes (13th-15th centuries)
Il contributo intende investigare la vita notturna di Bologna (Italia) nel periodo bassomedievale.
Attraverso l’analisi delle fonti statutarie redatte tra il xiii e il xv secolo, vengono descritti il ruolo degli
ufficiali impiegati nel controllo notturno, il disciplinamento attraverso norme preventive e di divieto,
e le attività permesse dalle autorità. I risultati ottenuti permettono di evidenziare un passaggio da una
supervisione locale della notte a una esercitata da magistrature forestiere che disciplinano con sempre
maggior attenzione anche la sfera morale. Allo stesso tempo, la vita notturna bolognese si caratterizza
per una certa dinamicità per via delle molte attività che si svolgevano al calar del sole.The contribution aims to investigate nightlife in Bologna (Italy) in the late medieval period. Through
the analysis of statute sources drafted between the 13th and 15th centuries, the role of the officers
employed in night control, regulation through preventive and prohibitory rules, and the activities
permitted by the authorities are described. The findings reveal a shift from a local supervision of the
night to one exercised by foreign magistrates who also increasingly regulated the moral sphere. At the
same time, Bolognese nightlife was characterised by a certain dynamism due to the many activities
that took place at nightfall.209187230,144Q2ESCIQ244,00,3210,0ERIH PLU
Pruning dead branches in gorgonian forests as an effective restoration tool against mortality events induced by global change
Marine animal forests are increasingly experiencing mass mortality events worldwide linked to anthropogenic impacts. The unprecedented impacts of climate change on marine habitats demand active restoration actions to enhance the resilience of key habitat-forming species. To this end, we tested the benefits of a novel restoration technique for habitat-forming gorgonians consisting of pruning dead apical branches and removing epibionts from dead basal branches, as a tool to implement nature-based management. By using the Mediterranean gorgonian Paramuricea clavata as a model, the effectiveness of pruning was assessed by comparing the demographic parameters of individually tracked pruned and control colonies (>1000 gorgonians) over a 3-yr study period. Here, we show that pruning contributed to a time-sustained improvement of health status of colonies (i.e., reducing colony partial mortality by ∼70 % and doubling the proportion of healthy colonies with 0–10 % partial mortality). Given the negative relationship between the extent of colony partial mortality and gorgonian performance, reducing partial mortality with pruning doubled colony survival and led to positive cascade effects that enhanced wound healing of denuded basal branches, growth on the apical tips of the colonies and branching, resulting in 2.5-fold higher live biomass growth rate compared to control colonies and contributing to revert the declining trend observed in natural populations. This study supports pruning gorgonians as a cost-effective, low-tech restoration technique that enhances natural resilience to improve the conservation status of worldwide gorgonian forests threatened by global change.91,9854,9Q1Q1SCI
Properties and Intermolecular Forces of Ionic Liquid Mixtures: The Archetypical Case of [EMIM][BF4] + [EMIM][EtSO4]
The properties and nanostructure of the Double Salt-Ionic Liquid formed by the combination of [1-ethyl-3-methylimidazolium][BF4] and [1-ethyl-3-methylimidazolium][EtSO4] in the whole composition range are studied by a combined experimental and molecular simulation approach. The measured physicochemical properties were analyzed in terms of deviations of ideality and its relationships with intermolecular forces. Quantum chemistry calculations of model clusters were carried out to infer nanoscopic aggregations, considering several mechanisms of interactions. Classical molecular dynamics simulations were carried out as a function of mixture composition, pressure, and temperature, allowing one to characterize structural, dynamic, and energetic properties of the considered mixed ionic liquids. The possible mechanisms of interaction of the involved molecules with biological targets, proteins, and model cell membranes were also computationally studied to infer molecular level roots of toxicological effects of mixtures of ionic liquids. This multiapproach-multiscale study provides for the first time a global characterization of mixtures of ionic liquids.17911774180,8113,8Q1Q2SCIE11,