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Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices
No full textChronic infection as a result of bacterial biofilm formation on implanted medical devices is a major global healthcare problem requiring new biocompatible, biofilm-resistant materials. Here we demonstrate how bespoke devices can be manufactured through ink-jet-based 3D printing using bacterial biofilm inhibiting formulations without the need for eluting antibiotics or coatings. Candidate monomers were formulated and their processability and reliability demonstrated. Formulations for in vivo evaluation of the 3D printed structures were selected on the basis of their in vitro bacterial biofilm inhibitory properties and lack of mammalian cell cytotoxicity. In vivo in a mouse implant infection model, Pseudomonas aeruginosa biofilm formation on poly-TCDMDA was reduced by ∼99% when compared with medical grade silicone. Whole mouse bioluminescence imaging and tissue immunohistochemistry revealed the ability of the printed device to modulate host immune responses as well as preventing biofilm formation on the device and infection of the surrounding tissues. Since 3D printing can be used to manufacture devices for both prototyping and clinical use, the versatility of ink-jet based 3D-printing to create personalised functional medical devices is demonstrated by the biofilm resistance of both a finger joint prosthetic and a prostatic stent printed in poly-TCDMDA towards P. aeruginosa and Staphylococcus aureus
Feldenkrais video
No full textThis Feldenkrais session was designed by a Feldenkrais practitioner to be used in a soma design workshop which aimed to improve aircraft passenger comfort
Body sheets/ soma trajectories
No full textIn this file, there are body sheets and soma trajectories which were used during soma-informed workshops
Raw Data for Magnetic order in a metal thiocyanate perovskite analogue
No full textData include:
- neutron diffraction data
- neutron diffraction refinement
- infrared spectrum
- bulk magnetic measurement
Raw data for new compounds described in the paper "Synthesis of New Morphinan Opioids by TBADT-Catalyzed Photochemical Functionalization at the Carbon Skeleton"
No full textRaw data for new compounds described in the paper "Synthesis of New Morphinan Opioids by TBADT-Catalyzed Photochemical Functionalization at the Carbon Skeleton
A linear, binary classifier to predict bacterial biofilm formation on polyacrylates
No full textResearch data and Python code to undertake machine learning to predict bacterial attachment to polyacrylates
Additional file 2 of Design decisions and data completeness for experience sampling methods used in psychosis: systematic review
No full text
SDT-Q600 raw data of verimilte-based composite material characterisation
No full textThe energy density test was performed on the SDT-Q600. which allows simultaneous Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC). In this test only TGA is required. Simultaneous Differential Scanning Calorimeter (TGA) measures transitions and reactions in materials in the range of ambient temperature to 1500 °C under air or nitrogen flow.
The test materials will include vermiculite-based composite and other thermochemical materials for comparision, including potassium formate with silica gel, vermiculite with MgCl2+MgSO4, vermiculite with LiCl+CaCl2, vermiculite with MgCl2+LiNO3, vermiculite with MgSO4+CaCl2, and vermiculite with MgSO4+MgCl2+LiNO3