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    2142 research outputs found

    Document Analysis Nvivo_How Stem sentences feature in textual discourse around the multiplicative conceptual field

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    An Nvivo and spreadsheet analysis of how stem sentences feature in textual discourse around the multiplicative conceptual field in boundary objects related to primary mathematics classrooms in England. Using a code book derived from Sfard's theory of commognition, documents were analysed by first assigning codes instrumentally on Nvivo then sorting in to a spreadsheet so all the codes could be looked at at once

    Force field parameter sets for 16 tetrahydroquinoline ligands

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    Force field parameter sets for free energy perturbation calculations of tetrahydroquinolines complexed to the first bromodomain of BRD4

    The future of manufacturing: utopia or dystopia?

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    Utopic and Dystopic videos of the vision of what the future of Digital Manufacturing Technologies might look like. These videos were used for a research study presented in the paper: The Future of Manufacturing: Utopia or Dystopia

    Single photon switch and facilitation induced transparency with dual-channel Rydberg interactions

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    Data for "Single Photon Switch and Facilitation Induced Transparency with Dual-channel Rydberg Interactions

    Single cell metabolic profiling of macrophages using 3D OrbiSIMS: correlations with phenotype

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    ABSTRACT: Macrophages are important immune cells that respond to environmental cues acquiring a range of activation status represented by pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes at each end of their spectrum. Characterizing the metabolic signature (metabolic profiling) of different macrophage subsets is a powerful tool to understand the response of the human immune system to different stimuli. Here, the recently developed 3D OrbiSIMS instrument is applied to yield useful insight into the metabolome from individual cells after in-vitro differentiation of macrophages into naïve, M1 and M2 phenotypes using different cytokines. This analysis strategy not only requires more than 6 orders of magnitude less sample than traditional mass spectrometry approaches, but also allows the study of cell-to-cell variance. Characteristic metabolites in macrophage subsets are identified using a targeted lipid and data driven multivariate approached highlighting amino acids and other small molecules. The diamino acids alanylsparagine and lipid sphingomyelin, SM(d18/16:0) are uniquely found in M1 macrophages while pyridine and pyrimidine are observed at increased intensity in M2 macrophages, findings which link to known biological pathways. The first demonstration of this capability illustrates the great potential of direct cell analysis for in-situ metabolite profiling with the 3D OrbiSIMS to probe functional phenotype at the single cell level using molecular signatures and to understand the response of the human body to implanted devices and immune diseases

    The effect of popping, a sustainable form of processing, on antinutritional factors in pulses - Data

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    Raw data associated with the research paper titled "The effect of popping, a sustainable form of processing, on antinutritional factors in pulses"

    The Lived Experience of Trainees and Supervisors regarding Mentoring in UK Postgraduate Medical Training: A descriptive phenomenological approach

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    The aim of this study is to better understand the phenomenon of mentoring that occurs in UK postgraduate medical training programs by describing it from the lived experiences of trainees and supervisors. The process will include interviewing trainees and supervisors from various programs in the UK, asking them to describe their lived experiences regarding the concept of mentoring as part of the trainee-supervisor relationship, as well throughout their career in general. Depending on what they say, themes will be deduced to summarize their descriptions of mentoring within their supervision (using the Colaizzi method of Data Analysis)

    Responsible Research and Innovation (RRI) prompts and practice cards (version 2.1, August 2022)

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    These printable cards highlight 18 different aspects of Responsible Research and Innovation (RRI) that may be relevant to researchers and innovators. You can use the cards to reflect on a project and plan RRI activities. You can use the cards to facilitate a discussion about priorities for RRI in a research or application area. Or do something completely different. Please note that there is now an updated version of these cards available: http://doi.org/10.17639/nott.735

    Factors influencing employers’ support for employees with acquired brain injuries or mental illness to return to- and stay in work: a qualitative systematic review

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    People with acquired brain injuries (ABIs) often experience residual disabilities and mental illnesses that restrict work participation. Employers are key in enabling successful return-to-work and work retention. Previous reviews focused on experiences of ABI survivors or people with mental illness during the return-to-work process and beyond. This review aimed to explore employers’ perspectives of factors influencing their support for people with ABIs or mental illness to return to- and stay in work

    Religiosity, Wellbeing, and Perception of Interreligious Threats

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    The onset of the COVID-19 pandemic and extended periods of lockdown worldwide have contributed to rising mental health issues, particularly among young adults. While there are many factors that contribute to one’s mental health, studies have also shown an ambivalent relationship between religiosity / spirituality and mental health, with religion often being used as a coping mechanism. Data is collected for this study with the aim to describe the relationship between religion and psychological wellbeing in the religiously diverse landscape of Malaysia by measuring the following elements: religiosity, religious emotions, interreligious perceptions of threats and discrimination, subjective wellbeing, and social-psychological wellbeing

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