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    2142 research outputs found

    Serial 3T MRI in early Parkinson’s to validate PD progression markers: Rationale and MRI analysis plan for nigral depigmentation at baseline, 6- and 12-months’ follow-up

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    Access to these files may be requested. Please contact Dr Xing at [email protected]. While NM-MRI has shown promise in diagnosing PD, its potential as a progression marker, particularly in the early stages when disease-modifying treatments are most effective, remains relatively unexplored. Our InsIghtPD study focuses on evaluating the substantia nigra, primarily looking at nigral depigmentation at baseline, 6- and 12-months’ follow-up. Secondary metrics, such as free water, kurtosis, and susceptibility, are also examined. Additionally, the study explores other whole brain metrics with potential as progression markers. The goal is to understand the minimal detectable change in these MRI metrics during the early clinical phase of PD. Furthermore, the study seeks to differentiate PD-related pathological changes from the effects of natural aging, which is critical for accurately assessing disease progression

    Data for paper: Magnetic framework composites via continuous flow syntheses for CO2 capture and other applications

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    Research data for the paper: Magnetic framework composites via continuous flow syntheses for CO2 capture and other application

    Scoring of interventions for cerebral small vessel disease

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    Excel sheet giving scoring calculations

    Defect-Induced Doping and Chemisorption of O2 in Se Deficient GaSe Monolayers

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    Original data for the Owing to their atomically thin nature, structural defects in two dimensional materials often play a dominating role in their electronic and optical properties. Here, we grow epitaxial GaSe monolayers on graphene/SiC by molecular beam epitaxy and characterise the layers by in situ scanning tunnelling microscopy and angle-resolved photoemission spectroscopy extracted from k-resolved photoemission electron microscopy mapping. We identify an electric dipole at the GaSe/graphene interface, with electrons accumulating on the GaSe, that cannot be compensated by p-type doping through the creation of defects formed by annealing in ultrahigh vacuum. Additionally, we demonstrate that both as-grown and defective GaSe layers are remarkably resilient to oxidation in a pure O2 environment, and chemisorption of O2 molecules on the surface can effectively electronically neutralise the doping in the layer. This work demonstrates the robust interlayer interaction in the GaSe/graphene van der Waals heterostructure and the role of defects on the doping for nanoelectronics

    Sufyan et al, Nanoscale Advances submission 2025

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    Raw data files for the figures in "Charge transfer dynamics in noble gas endofullerenes: intra- and extramolecular tunnelling", A. Sufyan et al, submitted to Nanoscale Adv. July 202

    Red rot in leather

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    Data collected during a collaboration between the University of Nottingham and the Natural History Museum on the acidic deterioration process termed 'red rot' in leather book bindings. This includes photos of the books, samples, and spectroscopical set ups, as well as the spectroscopical data collected

    Interview transcript data: Student midwives' experiences of challenging poor practice

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    MSc dissertation (IPA study) exploring students midwives' experiences of challenging poor practice whilst on placement. Contributing to the research supporting quality of care in maternity. Practice and education improvement aim

    Raw data for new compounds described in the paper "Silver(I)-Catalyzed Synthesis of Cuneanes from Cubanes and their Investigation as Isosteres"

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    Raw data for new compounds described in the paper "Silver(I)-Catalyzed Synthesis of Cuneanes from Cubanes and their Investigation as Isosteres

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