University of Nottingham
Nottingham Research Data Management Repository (University of Nottingham)Not a member yet
2142 research outputs found
Sort by
A feasibility study for a randomised control trial on the effects of engagement with a dental anxiety online peer support group
No full textThis data was collected as part of a PhD thesis which aimed to evaluate the feasibility of a Randomised Control Trial (RCT) on the effects of engagement with a Dental Anxiety (DA) Online Support Group (OSG) in an adult population.
This mixed-methods study recruited 40 participants with DA through social media within 3 months. Participants completed pre- and post- measures of DA and intention to attend routine dental care. They were randomised to a wait-list control or the OSG. Semi-structured interviews were conducted with OSG participants
Secondary ion mass spectrometry analysis of pentosan polysulfate
No full textPentosan polysulfate sodium (PPS) is a glycosaminoglycan mimetic that is the only current active pharmaceutical ingredient (API) for the oral treatment of interstitial cystitis. PPS is an inherently complex API due to variations in chain length, backbone structure, sulfation pattern and end group making discriminating between batch-to-batch as well as manufacturer-to-manufacturer differences difficult. In this study high throughput liquid handling and time-of-flight secondary ion mass spectrometry (ToF-SIMS) is used to enable the rapid chemical analysis (450 samples in 6 hours) of small amounts (≈150 ng) of PPS. Chemical discrimination between PPS produced by different manufacturers and, in one case, batch-to-batch variation of the same manufacturer is achieved. Analysis of samples using a 3D-OrbiSIMS instrument is used to provide confident assignment of the discriminating ions to enable structural interpretation of the variance observed between samples. Together with analysis of samples spiked with NaOAc or NaSO4, free sulphate and acetate along with sulphate pattern are implicated as key differences between manufacturers/batches. This approach is likely to be highly beneficial for the rapid quality control of PPS
RoboClean elicitation study data of spoken natural language instructions to a robotic vacuum cleaner
No full textDataset comprising spoken instructions of 21 participants tasked to address a robotic vacuum cleaner. The dataset includes transcribed instructions spoken by participants, timestamps, output messages triggered by matching a Wizard-of-Oz protocol (see this paper: https://doi.org/10.1145/3432942), and categorisations of the instructions
The Hub for Education for Refugees in Europe Knowledge Base: Technical Report and Framework
Full text linkThe Hub for Education for Refugees in Europe (HERE) provides a central reference point for information relating to refugee education throughout Europe in the form of a curated, searchable database of academic and non-academic resources on refugee education from across the continent, published since 2015. This is supported by the HERE Network which brings together interested parties and key stakeholders in the field of refugee education through online and face-to-face activities aimed at exchanging knowledge and developing research and practice on refugee education across Europe. This technical report begins by explaining the rationale and objectives behind the HERE knowledge base, followed by a description of the methodological steps taken to build the knowledge base. The report then illustrates how researchers in education for refugees in Europe can use the HERE knowledge base
Data from: Reproductive isolation in a three-way contact zone
No full textContact zones between divergent forms within a species provide insight into the role of gene flow in adaptation and speciation. Previous work has focused on contact zones involving only two divergent forms, but in nature many more than two populations may overlap simultaneously and experience gene flow. Patterns of introgression in wild populations are, therefore, likely much more complicated than is often assumed. We begin to address this gap in current knowledge by investigating patterns of divergence and introgression across a complex natural contact zone. We use phenotypic and genomic data to confirm the existence of a three-way contact zone between divergent freshwater resident, saltwater resident and saltwater migratory three-spined stickleback (Gasterosteus aculeatus) on the island of North Uist, Scottish Western Isles. We find evidence for hybridisation, mostly between saltwater resident and saltwater migratory forms. Despite hybridisation, genomic analyses reveal pair-wise islands of divergence between all forms that are maintained across the contact zone. Genomic cline analyses also provide evidence for selection and / or hybrid incompatibilities in divergent regions. Divergent genomic regions occur across multiple chromosomes and involve many known adaptive loci and several chromosomal inversions. Our results suggest that reproductive isolation is maintained in this three-way contact zone, despite some hybridisation, and that reduced recombination in chromosomal inversions may play an important role in maintaining this isolation
Additional file 5 of Effectiveness and implementation of interventions for health promotion in urgent and emergency care settings: an umbrella review
No full textAdditional file 3 of Modulation of long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression in the liver of Beagle dogs by Toxocara canis infection
No full textStakeholder input during development of TTEAM intervention
No full textThis study aimed to apply the intervention-mapping approach to co-design a self-guided, return-to-work toolkit for stroke survivors and employers. The intervention, known as TTEAM, was developed with input from stakeholders, including an expert advisory group, and employer participants who attended three online workshops. This data set includes the email invitation sent to the advisory group, the Powerpoint slides used within the advisory group meetings, and the PowerPoint slides used within the workshops attended by employer participants
Improving tic services in England (INTEND) survey data
No full textThe ImproviNg Tic services in EnglaND (INTEND) study explored current service provision for tics and Tourette syndrome in England by contacting NHS organisations. We also asked healthcare professionals working in children and young people’s services about their experience of assessing and treating tics and whether they felt they would benefit from more training in this area. We then worked with experts throughout England to develop a recommended care pathway for the referral, assessment and treatment of tics.
Responses from NHS organisations demonstrated that tic service provision was inconsistent and very limited across England. Only 12 service providers were identified as providing a full care pathway that offered both assessment and treatment, and 5 of these providers were located in London.
The national survey was completed by 184 healthcare professionals. They highlighted a lack of resources, including funding, training and national clinical guidelines for tics. Most survey respondents identified a need for further resources to support them with both assessing and treating tics, including training. FOI and national survey responses together emphasised that tic services need urgent improvement.
Experts rated 62 service features on their level of importance to include within a care pathway. Based on these ratings and a team workshop, a final 43 service features were approved to guide the design of the care pathway.
Our Patient and Public Involvement (PPI) panel consisting of ten parents/carers of young people with tics provided vital input throughout the study. They shared feedback on study findings, including how findings reflected their personal lived experiences. Their input on key aspects of the INTEND Pathway also ensured that its design suited the needs of young people with tics and their families
Shortest Distances on an Ellipsoid Using the Fast Marching Method
No full textESD : Ellipsoid Shortest Distance
ESD is a Python library for computationally determining shortest distances over the surface of an ellipsoid.
This is primarily done using the fast marching method (FMM) of Kimmel and Sethian, on a suitably defined mesh of the ellipsoid surface. This approach allows the computation of approximate distances between any pair of points on any ellipsoid (sphere, spheroid or triaxial) with great efficiency. Moreover, multiple distances can be computed from a particular start point using a single calculation. This makes the method particularly well suited to solving single source problems