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Organic Chemistry I Drill (CHEM 2210D) - 1st Module - Bonding - Sample B- Answer Key
Get PDFSample B Answer Key to Organic Chemistry I Drill Module 1
Organic Chemistry I Drill (CHEM2210D) - 3rd Module-Sample Problems
No full textThis module teaches Resonace, Using curved arrows and Acid-base reaction
Organic Chemistry I Drill (CHEM2210D) - Module 5- Sample Problems
No full textThis module deals with Alkanes
Organic Chemistry I (CHEM2210) - Practice Hour Exams - Answer Key
No full textAnswer key to Practice Exam
Organic Chemistry II Drill (CHEM2220D). Module 1. Sample B. Answer keys
No full textThis module teaches how to identify and explain the processes involved in proton ¹H and carbon-13 nuclear magnetic resonance (NMR) spectroscopy, and mass spectroscopy
Organic Chemistry II Drill (CHEM2220D) Module 2. Alcohols
Get PDFThis module teaches about alcohols and phenols; ethers and epoxides; thiols and sulfides
Organic Chemistry II Drill (CHEM2220D). Module 3. Sample Problems
Get PDFThis module teaches conjugated \u27PI\u27 systems and pericyclic reactions
Organic Chemistry II Drill (CHEM2220D) Module 6. Part A. Sample B. Answer key
Get PDFThis module deals with the structure of aldehydes and ketones
Organic Chemistry II Drill (CHEM2220D) Module 6. Part B. Sample Problems
Get PDFThis module deals with the structure of aldehydes and ketones
LncEGFL7OS Regulates Human Angiogenesis by Interacting with MAX at the EGFL7/miR-126 Locus
No full textIn an effort to identify human endothelial cell (EC)-enriched lncRNAs,~500 lncRNAs were shown to be highly restricted in primary human ECs. Among them, lncEGFL7OS, located in the opposite strand of the EGFL7/miR-126 gene, is regulated by ETS factors through a bidirectional promoter in ECs. It is enriched in highly vascularized human tissues, and upregulated in the hearts of dilated cardiomyopathy patients. LncEGFL7OS silencing impairs angiogenesis as shown by EC/fibroblast co-culture, in vitro/in vivo and ex vivo human choroid sprouting angiogenesis assays, while lncEGFL7OS overexpression has the opposite function. Mechanistically, lncEGFL7OS is required for MAPK and AKT pathway activation by regulating EGFL7/miR-126 expression. MAX protein was identified as a lncEGFL7OS-interacting protein that functions to regulate histone acetylation in the EGFL7/miR-126 promoter/enhancer. CRISPR-mediated targeting of EGLF7/miR-126/lncEGFL7OS locus inhibits angiogenesis, inciting therapeutic potential of targeting this locus. Our study establishes lncEGFL7OS as a human/primate-specific EC-restricted lncRNA critical for human angiogenesis