898 research outputs found
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Interview with Cardell Patterson, Flag Boy for the Uptown Warriors.
No full textInterview with Cardwell Patterson, Flag Boy for the Uptown Warriors, vy Kim Vaz-Deville. Cardwell Patterson talked about what it means to be a flag boy ( a messanger for the Big Chief), the history of his association with the Mardi Gras Indians, the suits he made, and the culture and traditions of the group.https://digitalcommons.xula.edu/masked/1011/thumbnail.jp
New Orleans Youth Master Plan Desired Results Statements.
Full text linkThe Desired Results Statements were informed by lived experiences and youth perspectives; local sector-based expertise; and researched youth development goals and frameworks. The Desired Results Statements will go on to inform the creation of action strategies and steps of the New Orleans Youth Master Plan, and will ensure that our efforts are aligned with our vision
New Orleans Youth Master Plan: Community Conversations Report
Full text linkThe New Orleans Youth Master Plan Community Conversations were held July-September 2020 via Zoom. Utilizing a human- centered design approach and an equity lens, a community of New Orleans youth and adults came together in an effort to redefine success and create innovative pathways to get there
Design & Synthesis of Small Molecules as Inhibitors of Cytochrome P450 2A6 for Tobacco Use Cessation
No full textCigarette smoking causes nearly one in every five deaths in the United States. The life expectancy of a smoker is 10 years less than a nonsmoker on average. Cigarette smoke contains more than 7,000 chemicals, seventy of which are known to cause cancer. Nicotine is responsible for the addictive and psychopharmacological effects of tobacco. Many tobacco components including nicotine are metabolized by cytochrome P450 enzymes. Nicotine is mainly metabolized by P450s 2A6 and 2A13. In this project, our goal is to design and synthesize selective metabolism-based inhibitors of P450 2A6. Such inhibitors can decrease the amount of tobacco chemicals metabolized into carcinogenic species. In addition, they can potentially be used for smoking cessation.https://digitalcommons.xula.edu/build_xula/1001/thumbnail.jp
Using bis-MPA as a platform for novel drug delivery systems
No full text2,2-bis(methylol)propionic acid (bis-MPA) dendrimers are ideal backbones for novel drug delivery systems. Bis-MPA based dendrimers tend to be stable with multiple terminal groups with potential for functionalization, making them excellent for use in targeted drug delivery. However, these dendrimers have low water solubility. Amphiphilic block copolymers, a class of Stimuli Responsive Polymers (SRPs), can be conjugated to the end of the dendrimer. This increases the water solubility of the molecule while simultaneously increases the efficiency of SRPs. Water solubility can be further increased through the addition of polyethylene glycol (PEG) as linkages between the dendrimer and the SRP. The efficiency of free SRPs will be compared to the efficiency of the novel vehicle to determine if the proposed materials are viable as drug delivery systems.https://digitalcommons.xula.edu/build_xula/1012/thumbnail.jp
Design and Synthesis of Ck1δ and Ck1ε Inhibitors as Therapeutics for Alzheimer\u27s Disease
No full textThe CK1 family of protein kinases are overexpressed in AD brains and have been linked with tau phosphorylation. For our study, we will be looking at two CK1 isoforms, CK1δ and CK1ε. Endogenous CK1δ greatly contributes to basal phosphorylation in the sample cells, while an overexpression of both isoforms saw a spike in tau phosphorylation. Previous studies have also shown that CK1δ can phosphorylate at least 15 sites in PHF-tau. We are trying to develop small-molecule kinase inhibitors that can better bind to tau protein than ATP, thereby reducing phosphorylation, maintaining cytoskeletal integrity, and stabilizing cell viability. Our research group has identified a series of compounds that function as ATP-competitive inhibitors of CK1d and CK1e. Docking studies are being performed for these compounds onto the X-ray crystal structure of CK1δ and CK1ε to understand the protein-inhibitor interactions. The results from the docking studies are presented here.https://digitalcommons.xula.edu/build_xula/1010/thumbnail.jp
Black Identity, Representation, and Identification in Comic Book Movies
Full text linkThe study of Black representation in comic book movies involving the variables representation, Black identity, and identification has never been done before. Black representation in comic book movies is a significant topic of study due to the prevalence of comic book movies in popular culture, because of the increasingly diverse casts of such films, and the impacts representation can have psychologically, socially, and historically. The researcher hypothesized that Xavier University of Louisiana students would identify more with comic book movie characters of the same race, and that stronger Black identity would be related to higher dissatisfaction with current Black representation in comic book movies. Representation was measured using the Bechdel-Wallace and DuVernay Tests, Black identity was measured with an abbreviated Multidimensional Inventory of Black Identity, and identification was measured with Cohen’s identification survey in relation to the Marvel Cinematic Universe characters Black Panther, Okoye, Iron Man, and Black Widow. The researcher found that race was relatively insignificant when examining identification scores, and that Black identity and representation were not significantly correlated. The results suggest that gender may have had a more defining role in participants’ level of identification with comic book movie characters, and that Black comic book movie characters fail to fully represent Black people, particularly Black females
1 - Visualizing Wealth and Personal Finance
Full text linkThis section focuses on the power of investment and demonstrates how interest can make funds grow exponentially!https://digitalcommons.xula.edu/data_instruct/1006/thumbnail.jp
4 - Visualizing Wealth and Personal Finance
Full text linkPart 4 of Visualizing Wealth and Personal Finance - should I get a car loan??https://digitalcommons.xula.edu/data_instruct/1010/thumbnail.jp
Interview with Ausettua Amor Amenkum, Big Queen of the Washitaw Nation and the Founder of Kumbuka African Drum and Dance Collective Reunion.
No full textThis is a video of an interview with Ausettua Amor Amenkum by Kim Vaz-Deville.
Ausetta Amor Amendum talks about the history of being associated with the Mardi Gras Indian culture, when she started, what it means to be a Big Queen, the suits she made and the connection between African Americans and the Native Americans.https://digitalcommons.xula.edu/masked/1012/thumbnail.jp