6867 research outputs found
Sort by
Transition in dietary quality: Evidence from India
No full textDespite significant economic growth over the past decades, poor nutritional status in India is a serious concern. The social transformation led by growth in income influences both the composition of food and the quality of diet consumed. Against this backdrop of changing lifestyles and the rise in obesity and non-communicable diseases, in this study, we examined changes in diet quality and the critical socio-economic correlates of this quality from 1983 to 2012 using three rounds of nationally representative surveys providing information on food consumption for more than 100 000 households in each round. We constructed diet quality indices at the household level using deficient and excess intake of macro and micronutrients compared with the recommended daily allowances (RDA) for different age-sex groups of the Indian population. We found that in relation to the RDA, fat consumption increased over time while protein and energy consumption decreased. The average diet quality index improved in the rural sector while it deteriorated in the urban sector. Caste and religion are significant correlates of the diet quality index. The deficiency index of nutrients decreased for poor households as they get richer; however, it increased with affluence level for the non-poor. It is suggested that the Indian Government may play a more proactive role in implementing coherent national policies in trade, food and agriculture to protect public health by promoting the demand for a healthy diet
Characterization of viruses in Phase 3 and Phase 3b trials (the Ring Study and the Dapivirine Ring Extended Access and Monitoring Trial) of the Dapivirine vaginal ring for human immunodeficiency virus type 1 infection risk reduction
No full textBackground: The Ring Study demonstrated 35.1% human immunodeficiency virus type 1 (HIV-1) infection risk reduction among participants who used the Dapivirine vaginal ring-004 (DVR), whereas the Dapivirine Ring Extended Access and Monitoring (DREAM) trial, approximated a 62% risk reduction. The observed non-nucleoside reverse-transcriptase inhibitor (NNRTI) resistance-associated mutations (RAMs) and effects on viral susceptibility are described here. Methods: Population-based genotyping on plasma samples collected longitudinally, and next-generation sequencing (NGS) and phenotypic susceptibility testing were done on plasma collected at seroconversion. Retrospective HIV-1 RNA testing was used to more accurately establish the time of infection. Results: In the Ring Study, NNRTI RAMs were not observed in most viruses at seroconversion (population-based genotyping: DVR: 71 of 84, 84.5%; placebo: 50 of 58, 86.2%). However, more E138A was found in the DVR group (E138A DVR: 9 of 84, 10.7%; placebo: 2 of 58, 3.4%; P = .2, Fisher exact test). NGS detected 1 additional mutation in each group (DVR: G190A; placebo: G190A and G190E). Marginal dapivirine susceptibility reduction was found with NNRTI RAMs at seroconversion (geometric mean fold-change, range: DVR, 3.1, 1.3–5.1; placebo, 5.8, 0.9–120). NNRTI RAMs were not emergent between first detectable HIV-1 RNA and seroconversion when these visits differed (paired samples, mean ring use: DVR, n = 52, 35 days; placebo, n = 26, 31 days). After stopping DVR, 2 of 63 viruses had emergent G190G/A or K103K/N with V106V/M at final study visit. Resistance profiles from the DREAM trial were consistent with the Ring Study. Conclusions: DVR showed little potential for selection of NNRTI-resistant variants
Exploring the urban gradient in population health: Insights from satellite-derived urbanicity classes across multiple countries and years in sub-Saharan Africa
No full textThe demographic, ecological and socioeconomic changes associated with urbanisation are linked to changes in disease incidence, health service provision and mortality. These effects are heterogeneous between and within urban areas, yet without a clear definition of what constitutes an ‘urban’ area, their measurement and comparison are constrained. The definitions used vary between countries and over time hindering analyses of the relationship between urbanisation and health outcomes, evaluation of policy actions and results in uncertainties in estimated differences. While a binary urban-rural designation fails to capture the complexities of the urban-rural continuum, satellite data augmented with models of population density and built-up areas offer an opportunity to develop an objective, comparable and continuous measure which captures urbanisation gradient at high spatial resolution. We examine the urban gradient within the context of population health. We compare the categorisation of urban and rural areas (defined by national statistical offices) used in household surveys in sub-Saharan Africa (SSA) to an urban-rural gradient derived from augmented satellite data within a geospatial framework. Using nine Demographic and Health Surveys (DHS) conducted between 2005 and 2019 in six SSA countries, we then assess the extent of misalignment between urbanicity based on DHS categorisation compared with a satellite-derived measure, while discussing the implications on the coverage of key maternal health indicators. The proposed indicator provides a useful supplement to country-specific urbanicity definitions and reveals new health dynamics along the rural-urban gradient. Satellite-derived urbanicity measures will need frequent updates to align with years when household surveys are conducted
Vaccines for a sustainable planet
No full textThe health of the planet is one objective of the United Nations’ Sustainable Development Goals. Vaccines can affect not only human health but also planet health by reducing poverty, preserving microbial diversity, reducing antimicrobial resistance, and preventing an increase in pandemics that is fueled partly by climate change
Coming Full Circle: Microbicide Development at the Population Council
No full textAn interactive webinar to provide audience members an opportunity to learn about and discuss microbicide development at the Population Council, from the articulation of the idea of a female-controlled HIV prevention method in the 1990s to today, when the dapivirine vaginal ring developed by IPM is being rolled out as the first microbicide product
Role of stigma in pre-exposure prophylaxis (PrEP) uptake and continuation among adolescent girls and young women (AGYW): Considerations for programme implementers
Get PDFA synopsis of a review of the role of PrEP-related stigma with practical considerations for programme implementers on strategies to reduce stigma
Validating midwifery professionals\u27 scope of practice and competency: A multi-country study comparing national data to international standards
No full textBackground: There is a global shortage of midwives, whose services are essential to meet the healthcare needs of pregnant women and newborns. Evidence suggests that if enough midwives, trained and regulated to global standards, were deployed worldwide, maternal, and perinatal mortality would decline significantly. Health workforce planning estimates the number of midwives needed to achieve population coverage of midwifery interventions. However, to provide a valid measure of midwifery care coverage, an indicator must consider not only the raw number of midwives, but also their scope and competency. The tasks midwives are authorized to deliver and their competency to perform essential skills and behaviors provide crucial information for understanding the availability of safe, high-quality midwifery services. Without reliable estimates for an adequate midwifery workforce, progress toward ending preventable maternal and perinatal mortality will continue to be uneven. The International Labor Organization (ILO) and the International Confederation of Midwives (ICM) suggest standards for midwifery scope of practice and competencies. This paper compares national midwifery regulations, scope, and competencies in three countries to the ILO and ICM standards to validate measures of midwife density. We also assess midwives\u27 self-reported skills/behaviors from the ICM competencies and their acquisition. Methods and findings: We compared midwives\u27 scope of practice in Argentina, Ghana, and India to the ILO Tasks and ICM Essential Competencies for Midwifery Practice. We compared midwives selfreported skills/behaviors with the ICM Competencies. Univariate and bivariate analysis was conducted to describe the association between midwives\u27 skills and selected characteristics. National scopes of practice matched two ILO tasks in Argentina, four in India, and all in Ghana. National standards partially reflected ICM skills in Categories 2, 3, and 4 (pre-pregnancy and antenatal care; care during labor and birth; and ongoing care of women and newborns, respectively) in Argentina (range 11% to 67%), mostly in India (range 74% to 100%) and completely in Ghana (100% match). 1,266 midwives surveyed reported considerable variation in competency for skills and behaviors across ICM Category 2, 3, and 4. Most midwives reported matching skills and behaviors around labor and childbirth (Category 2). Higher proportions of midwives reported gaining basic skills through in-service training and on-job-experience than in pre-service training. Conclusion: Estimating the density of midwives needed for an adequate midwifery workforce capable of providing effective population coverage is predicated on a valid numerator. A reliable and valid count of midwives to meet population needs assumes that each midwife counted has the authority to exercise the same behaviors and reflects the ability to perform them with comparable competency. Our results demonstrate variation in midwifery scopes of practice and self-reported competencies in comparison to global standards that pose a threat to the reliability and validity of the numerator in measures of midwife density, and suggest the potential for expanded authorization and improved education and training to meet global reference standards for midwifery practice has not been fully realized. Although the universally recognized standard, this study demonstrates that the complex, composite descriptions of skills and behaviors in the ICM competencies make them difficult to use as benchmark measures with any precision, as they are not defined or structured to serve as valid measures for assessing workforce competency. A simplified, content-validated measurement system is needed to facilitate evaluation of the competency of the midwifery workforce
The social, education, health, and economic effects of the COVID-19 pandemic on Kenya’s adolescents
No full textThe first case of COVID-19 was detected in Kenya in March 2020. Initial government responses included several containment measures such as school closures, movement limitations, and bans on public gatherings. These measures had many follow-on effects, in particular for the country’s vulnerable adolescents. Between June 2020 and February 2021 two round of quantitative data was collected in four counties in Kenya (Kilifi, Kisumu, Nairobi, and Wajir) via phone surveys (n = 3,921). In addition, qualitative in-depth interviews were conducted in person in November 2020 with adolescents, parents, and other key stakeholders (n = 234). Results showed that the pandemic’s effects on adolescents were wide-reaching and often differed by gender. While 85% of students reported doing some form of remote learning during school closures, 98% of them reported considerable challenges with less than one-third using technology (i.e., computers, phones, television, and radio) to support their learning. Over half of the adolescents reported depressive symptoms and over three-quarters reported skipping meals in the past week due to COVID-19. Twelve percent of girls and 9% of boys reported skipping healthcare services in the past one month, with the most common reason being lack of money to access the needed service. Once school had fully re-opened, 16% of girls and 8% of boys who were enrolled at the start of the pandemic had not re-enrolled. Given the wide, multi-sectoral nature of the impacts of the pandemic, a coordinated response involving education, health, and gender actors, as well as government and non-government partners, will be needed to mitigate the long-term negative impacts for Kenya’s adolescents, in particular girls and other marginalized groups
Webinar—Advancing Social and Behavior Change Measurement in Family Planning
No full textBreakthrough RESEARCH, USAID’s flagship social and behavior change (SBC) research and evaluation project to drive the generation, packaging, and use of innovative SBC research to inform programming, hosted its second of four interactive legacy and learning events on 28 February 2023.
This event in the series on SBC measurement highlighted evidence, insights, and learnings over the life of the project to advance SBC measurement to support and strengthen family planning programs. SBC approaches can support family planning programs, and the standardized measurement of these approaches guided by a defined theory of change is critical to understanding their effectiveness and contributing to their success
Breakthrough RESEARCH Behavioral Sentinel Surveillance (BSS) Survey: Midline
No full textThe Behavioral Sentinel Surveillance (BSS) survey undertaken by Breakthrough RESEARCH/Nigeria assessed the effectiveness of the Breakthrough ACTION/Nigeria integrated social and behavior change (SBC) activities for malaria, family planning, and maternal, newborn, and child health plus nutrition (MNCH+N) in Kebbi and Sokoto states relative to malaria-only SBC activities in Zamfara state. It focuses on women aged 15–49 years who are currently pregnant or with a child under 2 years living in areas targeted for integrated (Sokoto/Kebbi) and malaria-only (Zamfara) SBC programming. These are the study\u27s midline datasets. Due to security challenges during midline data collection, these data were collected only in Kebbi State. (2021