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Lessons for integrated social and behavior change programming: Exploring family planning, maternal and child health, and nutrition behavioral determinants in Niger
No full textThis Knowledge SUCCESS blog features work that Breakthrough RESEARCH\u27s Leanne Dougherty is leading in the Sahel region in Niger. Breakthrough RESEARCH has conducted mixed-methods analyses of the Resilience in the Sahel Enhanced (RISE) II, a USAID-funded program, integrated SBC implementation in the Maradi and Zinder regions of Niger, gathering information about its success and cost-effectiveness in this resource-constrained and drought-prone area
En quoi le changement climatique contribue-t-il à façonner les moyens de subsistance et les possibilités d\u27éducation des jeunes?
No full textBest Practices to Prevent and Respond to Sexual Violence: Evidence review and programme considerations
Get PDFPresentation for AGYW & South-to-South Learning Network Champions to fill a knowledge gap about what strategies have been tested and found effective in low- and middle-income countries (LMICs) to prevent and respond to sexual violence experienced by adolescent girls and young women (AGYW). This topic was identified by East and Southern African Champions as a key impediment to their HIV prevention programming efforts. This review focused on evidence from all 15 South-to-South Learning Network (SSLN) countries to gather and synthesise contextually relevant information
Vaginal microbiome, antiretroviral concentrations, and HIV genital shedding in the setting of hormonal contraception initiation in Malawi
No full textObjective: The aim of this study was to understand how vaginal microbiota composition affects antiretroviral concentrations in the setting of hormonal contraception initiation. Methods: Cervicovaginal fluid (CVF) concentrations of tenofovir, lamivudine, and efavirenz from 73 Malawian women with HIV were compared before and after initiation of depot-medroxyprogesterone acetate (DMPA) or levonorgestrel implant. We evaluated antiretroviral concentrations and vaginal microbiota composition/structure in the context of contraception initiation and predicted genital shedding using multivariable repeated measurements models fit by generalized estimating equations. Results: Mean lamivudine CVF concentrations decreased 37% 1month after contraception initiation. Subgroup analyses revealed a 41% decrease in women 1month after initiating levonorgestrel implant, but no significant difference was observed in DMPA group alone. Tenofovir, lamivudine, and efavirenz CVF concentrations were positively correlated with anaerobic bacteria associated with nonoptimal vaginal microbiota. Risk of genital HIV shedding was not significantly associated with tenofovir or lamivudine CVF concentrations [tenofovir relative risk (RR): 0.098, P=0.75; lamivudine RR: 0.142, P=0.54]. Lack of association between genital HIV shedding and efavirenz CVF concentrations did not change when adjusting for vaginal microbiota composition and lamivudine/tenofovir CVF concentrations (RR: 1.33, P=0.531). Conclusion: No effect of hormone initiation on genital shedding provides confidence that women with HIV on either DMPA or levonorgestrel implant contraception will not have compromised ART efficacy. The unexpected positive correlation between antiretroviral CVF concentrations and certain bacterial taxa relative abundance requires further work to understand the mechanism and clinical relevance
AGI-K REPORT Documentary 2023
No full textThe Adolescent Girls Initiative–Kenya is a long-term program being implemented by Population Council – Kenya. The initial two-year program for girls 11–14 years old in Wajir County, a marginalized county along the border of Somalia with low rates of girls\u27 school enrollment and high rates of child marriage, combined program activities that address inequitable gender norms at the community level, a household cash transfer conditioned on girls being in school and girls\u27 empowerment clubs with health and economic empowerment content. Population Council Kenya used a randomized controlled trial to evaluate the impact of the program and found that it had short- and long-term impacts on girls schooling and timing of marriage. This video describes the program and its potential for scale
Forecasting COVID-19 and other infectious diseases for proactive policy: Artificial intelligence can help
No full textHow to measure provider behavior change impact
Get PDFDeveloped by Breakthrough RESEARCH, this guide is intended to help program planners and designers better understand provider behavior change (PBC) initiatives and their impact on service delivery and quality. The guide is also meant to advance measurement of PBC by providing frameworks and illustrative examples of how PBC measurement can inform program planning and design. Finally, the guide offers ways to continue building the evidence base for PBC approaches and impact
