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Innovations in Data Visualization: Local patterns in young people’s health equity in the U.S.
Get PDFSocial and structural determinants of health (SSDoH) significantly impact equity among young people aged 10–24 in the US. Prior research shows that connectedness and support in school, family, and peer environments are crucial determinants of youth health and well-being. Understanding local variations in these relationships and their impact on health equity, while vital for policy and investment, remains a challenge. Council researchers explored relationships between select SSDoH and health outcomes among young people at sub-state levels to assess the potential of national survey data to inform decision-making & improve health equity
Mifepristone as a non-emergency contraceptive among women of reproductive age: A protocol for systematic review and meta-analysis
No full textBackground: Mifepristone is a selective progesterone receptor modulator with decades of data demonstrating its potential as a highly effective emergency as well as non-emergency contraceptive. Despite considerable evidence pointing to the potential effectiveness of mifepristone as a non-emergency contraceptive, no systematic review has been conducted to synthesise the available evidence. This systematic review aims to synthesise the current evidence on the use of mifepristone as a non-emergency contraceptive to prevent pregnancy among cisgender girls and women of reproductive age. Methods: We developed an electronic search strategy in collaboration with the research librarian. We will search five databases (Ovid Medline, CINAHL, EMBASE, Cochrane-Central Trials and Global Health) from inception and identify additional studies using several grey literature search strategies. All databases will be searched from inception, and we planned to complete the search by 30 June 2024. An Ovid Medline search strategy conducted on 24 May 2024 is provided as an example. We will include all studies that involve cisgender girls and/or women of reproductive age (defined as 54 years or younger), which assessed mifepristone as a non-emergency contraceptive to prevent pregnancy. The primary outcome is contraceptive effectiveness. Two independent reviewers will screen studies for eligibility through title, abstract, and full-text review. We will extract data with Covidence software using a Cochrane Effective Practice and Organisation of Care (EPOC)-adapted data-extraction tool and will assess risk of bias using the EPOC risk of bias tool and the Newcastle–Ottawa Scale. If sufficient data are available, we will conduct a meta-analysis using fixed and/or random effect models. However, if we are unable to conduct a meta-analysis, we will present the results narratively using the synthesis without meta-analysis guidelines and the EPOC table recommended for presenting findings without meta-analysis. Grades of Recommendation, Assessment, Development and Evaluation will be used to assess the quality of the evidence. We will report this review according to Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. Ethics and dissemination: This review is focused on secondary data and does not require any ethical approval. We aim to publish the review in a peer-reviewed scientific journal to promote knowledge transfer and present results using other knowledge translation mediums.
PROSPERO registration number CRD42024554720
i2i: Interventions to engage men and boys as clients, partners, and agents of change to improve SRHR
Get PDFEngaging men and boys in sexual reproductive health and rights (SRHR) is important for creating equitable health outcomes for all. While traditional SRHR initiatives often focus on women, men and boys must also be directly involved in their health. Backed by extensive evidence, this video explores ways to engage men and boys as clients, partners, and agents of change using a practical framework to help implementers and policymakers integrate male engagement strategies into their national SRHR health programmes
Ending child marriage in Zambia: Implications and considerations for accelerating progress in the context of Zambia’s Marriage (Amendment) Act No. 13 of 2023
Get PDFPopulation Council Kenya Annual Report 2024: Driving change through Research, Community Partnerships and Policy Insights
Get PDFGlobal trends in antibiotic consumption during 2016-2023 and future projections through 2030
No full textAntibiotic resistance is a global public health threat. Many factors contribute to this issue, with human antibiotic consumption being significant among them. Analyzing trends and patterns in consumption can aid in developing policies to mitigate the burden of antimicrobial resistance and global disparities in access to antibiotics. Using pharmaceutical sales data licensed from IQVIA, we estimate national-level trends in antibiotic consumption in 67 countries during 2016-2023 and analyze the effects of economic growth and the COVID-19 pandemic. Finally, we estimate global human consumption and project growth through 2030 assuming current trends. We find that estimated antibiotic consumption in reported countries increased 16.3% from 29.5 to 34.3 billion defined daily doses (DDDs) from 2016 to 2023, reflecting a 10.6% increase in the consumption rate from 13.7 to 15.2 DDDs per 1,000 inhabitants per day. Increases were most pronounced in upper-middle- and lower-middle-income countries. While the COVID-19 pandemic significantly reduced consumption globally, this was most pronounced in high-income countries, and in these countries, reductions in antibiotic use in 2020 were sharper, and lasted longer, than in other countries. By 2030, we project that, without reductions in rapidly developing nations, such as investments to improve infrastructure, particularly water and sanitation, along with improved access to vaccination, global antibiotic consumption will increase by 52.3% from an estimated 49.3 billion in 2023 to 75.1 billion DDDs
A drug-drug interaction study to evaluate the effects of strong CYP3A induction and inhibition on the pharmacokinetics of Segesterone Acetate and Ethinyl Estradiol from the Annovera® contraceptive vaginal system
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The challenges of measuring girls\u27 empowerment
No full textAfrica stands at a crossroads, with its future prosperity hinging on the policy and investment decisions it makes today. The continent has an opportunity to shape the trajectories of generations to come by investing in the success of a pivotal population: its adolescent girls. With over 145 million adolescent girls calling Africa home, the potential for transformative change is immense. Yet challenges persist: from high rates of child marriage to limited educational opportunities. Over half of African girls ages 15 to 19 are out of school or married or have children. How can African countries overcome these challenges to ensure that adolescent girls enter adulthood empowered to thrive? Pathways to Prosperity for Adolescent Girls in Africa, published by the World Bank, offers a groundbreaking road map for change
Una exploración del panorama de las jóvenes feministas organizadas en Kenia y México
No full textEl Population Council-Kenia y el Population Council-México se unieron a jóvenes feministas organizadas (JFO), académicas feministas y otras partes interesadas para llevar a cabo una investigación-acción participativa (IAP). Esta investigación tenía como objetivo comprender mejor el panorama de las JFO en Kenia y México, incluyendo su organización, operaciones, retos y experiencias compartidas. El estudio ofrece una visión general de las feministas organizadas y colectivas dirigidas por jóvenes en Kenia y México, y abarca diversos aspectos, como las características demográficas y contextuales, las áreas de interés principales, los métodos de comunicación y colaboración, la situación jurídica, la financiación y las poblaciones destinatarias, es decir, los programas, intervenciones o acciones grupales a los que se dirigen