Indonesian Journal of Medicine (IJM)
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The Effect of Snake Fish Extract (Channa striata) on Post Cesarean Section Wound Status in Postpartum Anemia Mothers
Get PDFBackground: A labor with Sectio Caesarea (SC) will increase mortality rate, which is twice the rate of vaginal delivery. The morbidity rate is also higher in SC delivery due to post-SC wound infection. Post-SC wound healing requires high albumin. This study is intended to determine the effect of snake fish extract on post-SC wound status in postpartum anemia women.Subjects and Method: This was a true experimental study with randomized control group post-test design. The study was conducted at Hj. Anna Lasmanah Hospital, Banjarnegara, Central Java, in May to June 2018. The population of all post-partum postpartum mothers was anemia. A sample of 30 study subjects was selected by stratified random sampling, consisted of 15 study subjects in intervention and control groups. The dependent variable was post-SC wound. The independent variable was snake fish extract. Post-SC wound was measured by REEDA scales. The data was analyzed by General Linear Model Repeated Measure.Results: In day-5, post-SC wound in the intervention group (mean= 0.27; SD= 0.46) was lower than control group (mean= 1.07; SD= 0.80) and it was statistically significant (p= 0.002).Conclusion: Channa striata extract can accelerate post-SC wound healing.Keywords: Channa striata extract, wound status, sectio caesarea, anemiaCorrespondence
Serum Ferritin as a Predictor of Shock in Children with Dengue Infection
Get PDFBackground: Dengue shock syndrome causes high morbidity and mortality among children worldwide. Several laboratory monitoring can be used to evaluate the progressivity of dengue virus infection. This study aimed to analyze ferritin serum as a predictor of shock in children with dengue infection, and to determine the cut off point that can be used to diagnose dengue shock.Subjects and Method: This was a cross sectional study conducted at pediatric ward, Dr. Moewardi hospital Surakarta Dr. Soetrasno hospital Rembang, Central Java. Study population was children aged less than 18 years old with dengue infection. Study subjects were selected by consecutive sampling. Tha dependent variable was dengue shock. The independent variable was serum ferritin concentration. Mann Whitney test was used to compare mean ferritin concentration between children with and without dengue shock. Cut off point of serum ferritin concentration was determined by ROC curve.Results: Mean serum ferritin concentration in children with dengue shock (mean= 3628.8; SD= 1582.4) was higher than in children without dengue shock (mean= 717.8; SD= 695.8), with p<0.001. Therefore, there was a statistically significant asssociation between serum ferritin concentration and dengue shock . The cut off point of serum ferritin concentration that could be used to show dengue shock with high sensitivity (0.92) and specificity (0.97) was 2304.5.Conclusion: High serum ferritin concentration is a predictor of dengue shock.Keywords: ferritin, dengue shock syndrome, childrenCorrespondence: Putri Evalda. Dr. Moewardi Hospital, Jl. Kolonel Sutarto No.132 Jebres, Surakarta, Central Java 57126. Email: dr. [email protected]. Mobile: 081227970440Indonesian Journal of Medicine (2017), 2(3): 154-160https://doi.org/10.26911/theijmed.2017.02.03.0
Path Analysis on the Social, Economic, and Cultural Determinants of Male Contraceptive Use in Family Planning Village, Yogyakarta, Indonesia
Get PDFBackground: One of today's global problems is the rapid growth of population. Population growth can be controlled through contraceptive method utilization. However, contraceptive use among males in most developing countries, including Indonesia, remains low. This study aimed to determine the social, economic, and cultural factors affecting male contraceptive use in family planning village, Yogyakarta, Indonesia, using Theory of Planned Behavior (TPB) and path analysis.Subjects and Method: A case-control study was carried out in Yogyakarta, Indonesia. A sample of 200 men aged 15 to 49 years was selected for this study by fixed disease sampling. The dependent variable was male surgical contraceptive method use. The independent variables were age, knowledge, education, intention, attitude, perceived behavior control, subjective norm, social culture, access to health service, and health service quality. The data were collected by questionnaire and analyzed by path analysis.Results: Male surgical contraceptive method use was directly affected by older age (b = 1.50; 95% CI = 0.54 to 2.46; p= 0.002), better knowledge (b= 1.48; 95% CI= 0.48 to 2.49; p= 0.004), stronger intention (b= 1.10; 95% CI= 0.15 to 2.06; p= 0.24), more positive attitude (b= 1.33; 95% CI= 0.35 to 2.30; p= 0.008), stronger perceived behavior control (b= 1.21; 95% CI= 0.23 to 2.20; p= 0.016), better access to health service (b = 1.59; 95% CI = 0.58 to 2.59; p= 0.002), better health service quality (b= 1.17; 95% CI= 0.22 to 2.12; p = 0.016), and supportive subjective norm (b= 2.07; 95% CI= 1.12 to 3.01; p<0.001). It was also indirectly affected by subjective norm, social culture, education, education, and access to health service.Conclusion: Male surgical contraceptive method use is directly affected by age, knowledge, intention, attitude, perceived behavior control, access to health service, health service quality, and subjective norm. It is indirectly affected by subjective norm, social culture, education, education, and access to health service.Keywords: male, contraceptive method, use, determinants, path analysisCorrespondence: Bettya Kartikasari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: +6285817606484.Indonesian Journal of Medicine (2018), 3(2): 89-98https://doi.org/10.26911/theijmed.2018.03.02.0
Association Between Exclusive Breastfeeding and the Risk of Tonsilitis in Children Under Five in Demak, Central Java
Get PDFBackground: Upper respiratory infection (URI) remains one of the primary causes of child mortality in Indonesia. Some studies have shown that exclusive breastfeeding can prevent various infectious diseases including URI. However, in some places the incidence of tonsilitis is still high although target of exclusive breastfeeding coverage has been met. This study aimed to determine association between exclusive breastfeeding and the risk of tonsillitis in children under five in Demak, Central Java.Subjects and Method: This was a cross sectional study conducted at 3 Community Health Centers, Demak, Central Java, from March to April 2017. A sample of 35 children under five years old were selected for this study. The dependent variable was the incidence of tonsillitis. The independent variable was history of exclusive breastfeeding. The data were collected b
Predictors of Macro and Microvascular Complication in Type 2 Diabetes Mellitus Patients at Dr. Moewardi Hospital, Surakarta
Get PDFBackground: Type 2 Diabetes Mellitus (Type 2 DM) is one of the major causes of morbidity and mortality worldwide. Morbidity and mortality due to diabetes are associated with the development of various microvascular complications (retinopathy, nephropathy, and neuropathy) and macrovascular complications (coronary heart disease, stroke, and peripheral vascular disease). This study aimed to examine the determinants of biopsychosocial macro and microvascular complications in patients with type 2 DM at Dr. Moewardi Surakarta.Subjects and Method: This was an analytic observational with a case-control design. The study was conducted at Dr. Moewardi, Surakarta, Central Java, from January to March 2018. A sample of 75 Type 2 DM cases with complication and 75 Type 2 DM cases without complication was selected for this study by fixed disease sampling. The dependent variables were macro and microvascular complications. The independent variables were body mass index (BMI), blood pressure, quality of life, depression, duration of disease, physical activity, diet, medication adherence, health financing, and routine blood sample. Clinical data were taken from medical record. The data of other variables were collected by a set of pre-tested questionnaire. Logistic regression was employed for data analysis.Results: The risk of macro and microvascular complications in type 2 DM patients increased with high BMI (OR= 22.00; 95% CI= 7.50 to 64.52, p<0.001), poor quality of life (OR= 7.06; CI 95%= 3.51 to 14.16, p<0.001), depression (OR= 3.30; 95% CI= 1.39 to 7.79, p= 0.007), longer duration of disease (OR= 9.71; 95% CI= 2.79 to 33.71, p<0.001), lack of physical activity (OR= 8.16; 95% CI= 1.23 to 53.93, p=0.029), poor diet (OR= 3.58; 95% CI= 1.39 to 9.18, p=0.008), poor medication adherence (OR= 4.54; 95% CI= 1.71 to 12.05, p=0.002), and irregular blood sample control (OR= 5.80; 95% CI= 1.97 to 14.65, p=0.001).Conclusion: The risk of macro and microvascular complications in patients with type 2 DM is determined by BMI, quality of life, depression, duration of disease, physical activity, diet, medication adherence, and blood sample control.Keywords: biopsychosocial, macrovascular, microvascular, complications, type 2 DMCorrespondence: Handoko. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36 A, Surakarta, Indonesia. Email: [email protected]. Mobile: +6285225591917.Indonesian Journal of Medicine (2018), 3(1): 1-13https://doi.org/10.26911/theijmed.2018.03.01.0
The Relationship of Radiological Value and Functional Scale of Lower Motion Devices in Patients with Bone Defects Given Synthetic Bone Graft and BMP2
Get PDFBackground: Broken bones in a severe lower motion device, especially those associated with a bone defect, often fail or are slow to fuse. The possibility of non-union in patients triggering clinicians to use bone-grafting as part of a procedure aims at achieving the union. The Gold Standard is to use autogenous bone graft, but it actually has some disadvantages. To overcome this, there are alternative measures of bone grafting. Hydroxyapatite is known to be synthetic bonegraft which has good osteoconductive properties. For hydroxyapatite, it has been widely used and easily available. Bone morphogenetic proteins (BMPs) are the family of osteo-inductive proteins in the bone matrix. This study aims to evaluate the effectiveness of synthetic bone graft and BMP-2 as a bonegraft in the process of bone healing with "bone defect" in long bones by evaluating the process of radiological closure of defects and clinical bone healing process.Subjects and Method: This was a cross sectional study. A sample of 20 patients with bone defect in the tibia and femur was selected for this study. An evaluation of radiological defect closure was evaluated using a calculation system using the FDA-determined radiological evaluation method and a periodic lower function of the LEFS (Lower Extremity Functional Scale) every 2 months up to the 6th month. The statistical tests were performed using linear regression.Results: There is a negative relationship between the radiological value and the functional scale of the lower motion device (b = -1.26; p = 0.001). There is an improvement in bone defect closure and clinical functional improvement in patients who performed a synthetic bonegraft closure action added by BMP-2 as well. The evaluation is carried out through radiological calculations that show a periodically reduced size of the defect which affects the increase in the value of the functional scale of the lower motion device.Conclusions: There is a negative relationship between radiological values and functional scale of lower motion devices in patients with bone defect in the tibia bone or femur given synthetic bone graft and Bmp2.Keywords: bone defects, synthetic bone grafts and BMP-2, LEFSCorrespondence
The Effect of Toluene Exposure on Central Nervous Disorder among Printing Workers
Get PDFBackground: The use of toluene in printing dominates the use of metal chemicals. Toluene is used in 75% of printing work activities. Accumulation of toluene concentrations in printing can cause health problems to workers. The purpose of this study was to analyze the effect of toluene exposure on central nervous system disorders in printing industry workers.Subjects and Method: This study was cross-sectional in the printing industry in Medan, North Sumatra. The population consists of 50 people with consecutive sampling technique sampling. Data on subjective symptoms of central nervous system disorders were measured by the German version of the Q18 questionnaire. The data were analyzed using multiple logistic regression tests.Results: Subjective symptoms of central nervous system disorders increased with tenure ≥2 years (OR = 4.19; p = 0.018) and smoking (OR = 8.91; p = 0.001). Subjective symptoms of central nervous system disorders decreased with age ≤30 years (OR = 0.17; p = 0.004), female sex (OR = 0.50; p = 0.002).Conclusions: The most dominant variable affecting the subjective symptoms of central nervous system disorders is the smoking habit variable with a probability value of 0.92 or 92%.Keywords: subjective symptoms, central nervous system disorders, workers, a printing industryCorrespondence: Samuel Marganda. Department of Environmental Health, Faculty of Public Health, Universitas Sumatera Utara, Medan, North Sumatera. Email: [email protected]. Mobile: 085362985340.Indonesian Journal of Medicine (2018), 3(3): 125-133https://doi.org/10.26911/theijmed.2018.03.03.01
The Difference of Bovine Bone Graft and Iliac Crest Bone Graft Effect on Closure of Bone Defect in Alveolar Bone Graft in Dr. Moewardi Hospital and Panti Waluyo Hospitals, Surakarta
Get PDFBackground: Cleft lip and palate (CLP) is a case of craniofacial congenital abnormalities that are often found by plastic surgeons. Successful management requires good surgical techniques, deep understanding of anatomical abnormalities and three-dimensional aspects of facial aesthetics. The Alveolar bone graft (ABG) aims to unite and stabilize Maxilla before definitive orthodontic action and restoration of dental care. The use of bone grafts in the surgical field is often done, aimed at maximizing the process of bone healing. Autogenous bone graft is the gold standard bone graft material because it contains all the properties needed in bone formation. The iliac crest bone graft (ICBG) is the most commonly used donor. Bromine bone graft (BBG) is increasingly being used as a substitute for autogenous bone graft. The purpose of this study was to determine the differences in the effect of the percentage of defect closure between CNG and ICBG on the closure of defects in ABG.Subjects and Method: The retrospective cohort study was conducted at Dr. Moewardi and Panti Waluyo Hospitals, Surakarta, Central Java, Indonesia, from February to April 2018. The dependent variable was bone defect closure. The independent variables were bovine bone and iliac crest bone grafts. The data were analyzed by Mann-Whitney.Results: Most patients after ABG surgery have a percentage of bone defect closure of 75-100% with bone resorption of 0-25% and include type I Bergland scale, where ICBG (66.7%) tends to be better than BBG (55.6%), but statistically not significant (p value = 0.678).Conclusion: There is no difference in the effect of the percentage of defect closure between CNG and ICBG on the closure of defects in ABG. ICBG tends to give a better percentage of defect closure than CNG, but it is not statistically significant.Keywords: Cleft lip and palate (CLP), Alveolar bone graft, bovine bone graft, Iliac crest bone graft, closure of bone defects.Correspondence: Ruzbih Bahtiar. Department of Surgery, Dr. Moewardi Hospital, Surakarta/Faculty of Medicine, Universitas Sebelas Maret. Indonesian Journal of Medicine (2018), 3(3): 151-161https://doi.org/10.26911/theijmed.2018.03.03.0
The Effect of Neoadjuvant Chemotherapy on HIF-1α Expression in Cervical Uterine Cancer
Get PDFBackground: Uterine cervical cancer is one of the main causes of female death related to cancer. Neoadjuvant chemotherapy aims to reduce tumor mass to allow radical surgery. HIF-1α is thought to have a key role in the development of cancer and the main target for chemoprevention.Objective: This study aims to prove the effect of neoadjuvant chemotherapy on HIF-1α expression in uterine cervical cancer as an assessment parameter for chemotherapy response. Subjects and methods: The study was carried out in the Department of Obstetrics and Gynecology and the Pathology Department of Anatomy Dr. Moewardi - Faculty of Medicine, Sebelas Maret University, Surakarta. Thirty (30) cervical cancer samples that met the inclusion and exclusion criteria were examined for HIF-1α expression before and after giving 3 times neoadjuvant chemotherapy. Examination using immunohistochemical methods. Data analysis using t-test.Results: Mean HIF-1α expression before administration of neoadjuvant chemotherapy 5.10± 1.174 cell/field, after administration of neoadjuvant chemotherapy 4.00±1.174 cell/field with p=0.001.Conclusion: Neoadjuvant chemotherapy has an effect on reducing HIF-1α expression in uterine cervical cancer.Keywords: neoadjuvant chemotherapy, HIF-1α, uterine cervical cancerCorrespondence: Sri Sulistyowati. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret. Mobile: 08122968215. email: [email protected] Indonesian Journal of Medicine (2018), 3(2): 119-124https://doi.org/10.26911/theijmed.2018.03.02.0
The Effects of Glucomannan Hydrolysates and BV Gel on Nugent Score, Treg Cell Percentage, and TGF-? level in Bacterial Vaginosis
No full textBackground: Bacterial vaginosis is commonly experienced by women of reproductive age. The Nugent score is the gold standard for diagnosing bacterial vaginosis. Prebiotic Glucomannan h