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The critical effect: Exploring the influence of critical media literacy pedagogy on college students’ social media behaviors and attitudes
Get PDFThis self-exploratory pilot qualitative study examines the impact of critical social media pedagogy on students’ behavior and attitudes toward social media. This study employs a critical lens of course content and self-reported student data from 18 participants who completed a Northern California university course titled “Social Media, Social Change” in the fall of 2019. The changes in participants’ social media behaviors and attitudes were measured via a pre-and post-survey designed by the researcher. Exposure to critical pedagogy was associated with changing views of social media, especially heightened privacy concerns. The study reveals areas of further research and recommendations for educators to effectively teach critical media literacy
Improving children’s wellbeing through media literacy education: An Irish study
Get PDFVia diverse content including programmes, songs and child-led social media channels, children are constantly exposed to commercially funded messages encouraging purchase behaviour. While there is no definitive agreement that advertising to children is detrimental to their wellbeing (Rowthorn, 2019), there is an enduring concern over the unintended effects of advertising on children (Opree et al., 2019). A substantive body of literature advocates for media literacy education to enable children to critically assess the content of marketing messages (De Pauw et al., 2018; Nelson, 2016). However, there is a dearth of research focusing specifically on the relationship between media practices of children, in terms of activities and competencies, and their wellbeing at pre-teen ages (Swist et al., 2015). This study responds to that gap by piloting a recently launched media literacy intervention designed to complement wellbeing curriculum in Irish primary schools, exploring if media literacy competences can improve children’s wellbeing
Inhibitory Effects of Cannabinoids on Acetylcholinesterase and Butyrylcholinesterase Enzyme Activities
Get PDFIntroduction: Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two cholinergic enzymes catalyzing the reaction of cleaving acetylcholine into acetate and choline at the neuromuscular junction. Abnormal hyperactivity of AChE and BChE can lead to cholinergic deficiency, which is associated with several neurological disorders including cognitive decline and memory impairments. Preclinical studies support that some cannabinoids including cannabidiol (CBD) and tetrahydrocannabinol (THC) may exert pharmacological effects on the cholinergic system, but it remains unclear whether cannabinoids can inhibit AChE and BChE activities. Herein, we aimed to evaluate the inhibitory effects of a panel of cannabinoids including CBD, Δ8-THC, cannabigerol (CBG), cannabigerolic acid (CBGA), cannabicitran (CBT), cannabidivarin (CBDV), cannabichromene (CBC), and cannabinol (CBN) on AChE and BChE activities. Methods: The inhibitory effects of cannabinoids on the activities of AChE and BChE enzymes were evaluated with the Ellman method using acetyl- and butyryl-thiocholines as substrates. The inhibition mechanism of cannabinoids on AChE and BChE was studied with enzyme kinetic assays including the Lineweaver-Burk and Michaelis-Menten analyses. In addition, computational-based molecular docking experiments were performed to explore the interactions between the cannabinoids and the enzyme proteins. Results: Cannabinoids including CBD, Δ8-THC, CBG, CBGA, CBT, CBDV, CBC, and CBN (at 200 µM) inhibited the activities of AChE and BChE by 70.8, 83.7, 92.9, 76.7, 66.0, 79.3, 13.7, and 30.5%, and by 86.8, 80.8, 93.2, 87.1, 77.0, 78.5, 27.9, and 22.0%, respectively. The inhibitory effects of these cannabinoids (with IC50 values ranging from 85.2 to \u3e200 µM for AChE and 107.1 to \u3e200 µM for BChE) were less potent as compared to the positive control galantamine (IC50 1.21 and 6.86 µM for AChE and BChE, respectively). In addition, CBD, as a representative cannabinoid, displayed a competitive type of inhibition on both AChE and BChE. Data from the molecular docking studies suggested that cannabinoids interacted with several amino acid residues on the enzyme proteins, which supported their overall inhibitory effects on AChE and BChE. Conclusion: Cannabinoids showed moderate inhibitory effects on the activities of AChE and BChE enzymes, which may contribute to their modulatory effects on the cholinergic system. Further studies using cell-based and in vivo models are warranted to evaluate whether cannabinoids’ neuroprotective effects are associated with their anti-cholinesterase activities
Colistin-associated Stevens-Johnson syndrome and toxic epidermal necrolysis reactions: a retrospective case-non-case pharmacovigilance study
Get PDFBackground: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening skin reactions. Colistin is a last resort antibiotic with a historically poor safety profile. The association between colistin and SJS/TEN has not been previously quantified.
Research design and methods: We identified colistin and SJS/TEN adverse event reports from the Food and Drug Administration Adverse Event Reporting System (FAERS) and calculated effect estimates using OpenEpi.
Results: From January 2013 through March 2021, 964 adverse events were reported for colistin. Colistin was listed as a secondary suspect drug in 13 SJS/TEN adverse event reports (1.3%), with a reporting odds ratio of 29.6 (95% confidence interval [CI] 17.1–51.1), and proportional reporting ratio of 29.2 (95% CI 17.0–50.2). Limitations of any FAERS study include the voluntary nature of reporting, unclear causal relationship between drug and adverse reaction, underreporting, and wide confidence intervals for rare adverse events like SJS/TEN.
Conclusions: Colistin was not the primary suspect drug in any SJS/TEN adverse event reports. We did identify a statistically significant safety signal for SJS/TEN with colistin as a secondary suspect drug. SJS/TEN is not currently included in the colistin product label. This association should be further explored in other pharmacoepidemiologic drug safety studies
E-Commerce Merchandising
Get PDFKelly Collins, a recent TMD graduate, walked the audience through her career timeline. During college and immediately after graduation, she worked as an Executive Assistant to a PR fashion firm in New York City. Aspiring to the “glossy” life of NYC fashion, Collins admitted that she was more caught up in the image of her job than its actual functions. After realizing that a tumultuous and erratic work environment was not for her, she accepted a position at interior textile company, Kravet Fabrics Inc., where she is currently Director of E-Commerce. During the pandemic, the company realized that they needed to improve their digital presence to gain sales because former hands-on selling strategies no longer worked
Hope Global Manufacturing
Get PDFHope Global manufactures creative engineered solutions worldwide that are customized to buyer’s needs. Their manufacturing locations are in Rhode Island, Mexico, Czech Republic, and China. They have diversified their product line since their founding in 1883 to serve a variety of industries such as apparel, automotive, industrial, and the government. Some of the products within these lines are shoelaces, drawstrings, cords, mesh, carpet strips, netting, beaded profiles, and clips. During the pandemic, Hope Global produced 3 million ear loops for face masks
Beyond Journals and Books: Keeping KBART Relevant in a Changing Information Landscape
Get PDFSlides for a presentation, Beyond journals and books: Keeping KBART relevant in a changing information landscape , presented at Camp ER&L 2022: 17th Meeting of the Electronic Resources and Libraries Conference on March 16, 2022. The conference was held online due to COVID-19.
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Abstract:
Supporting multimedia and non-traditional content are key components of KBART Phase III. Members of NISO’s KBART Standing Committee will discuss the details, including the new fields and how they affect electronic resource access and management. We will leave time for feedback, especially about how proposed changes affect different stakeholder’s workflows.
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The link leads to a session description on the conference website at https://mtgsked.com/p/31406/s.
Additional files include a PDF of the Powerpoint slides for the presentation, a printout of the session description on the conference website, and the contents of the chat discussion held on Pheedloop