Linfield College

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    11603 research outputs found

    Appreciation from Afar: How Chileans Perceive Independence as Distance from Family

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    While still in the midst of their study abroad experiences, students at Linfield University write reflective essays. Their essays address issues of cultural similarity and difference, compare lifestyles, mores, norms, and habits between their host countries and home, and examine changes in perceptions about their host countries and the United States. In this essay, Jordan Worthington describes observations during study abroad in Chillan, Chile

    Building Our Future Together

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    How Linfield turned the voice of the community into a plan for the futur

    Guide to the Linfield Tennis Collection

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    This collection contains materials documenting the Linfield Men’s and Women’s Tennis teams over a span of nearly two decades, collected by Tennis head coach, Carl Swanson

    Discussing Complex Issues Using Case Studies

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    Faculty Teaching Learning Lunch FTLL presented by Wendy Sagers, ELCP Coordinator Wednesday, October 5 from 12 – 1 pm, in Dillin Northwest Dining Room The case method is a way of considering the pros and cons of various solutions to a complex problem. Come discuss ways to use case studies in your classroom or club. See examples of how they are commonly used and ways to adapt them to your situation or topic. Lunch provided by the Lacroute Initiative

    The Final Few Weeks

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    Postcard from Felicity Fulton, during the Linfield University Semester Abroad Program, Fall 2022, at Aix en Provence in France

    San Pedro de Atacama

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    Coming Together at the Table

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    While still in the midst of their study abroad experiences, students at Linfield University write reflective essays. Their essays address issues of cultural similarity and difference, compare lifestyles, mores, norms, and habits between their host countries and home, and examine changes in perceptions about their host countries and the United States. In this essay, Tia Elder describes observations during study abroad in France

    Table of Contents

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    Table of contents for Volume 18, Issue 1 of the Linfield Magazin

    Worth 1,000 Words

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    Life at Linfield through the lens of a camer

    Elucidating the role of Exo1 and Mre11 mutations in DNA damage response

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    DNA double strand breaks (DSBs) are one of the most deleterious types of DNA damage that cells combat. DSBs are processed by the 3′-to-5′ exonuclease activity of the DSB repair nuclease, Mre11, to generate protruding 3′ single stranded DNA (ssDNA) at DSBs. Exonuclease 1 (EXO1) is an evolutionarily, well-conserved exonuclease. Its ability to resect DNA in the 5′-3′ direction has been extensively characterized and shown to be implicated in several genomic DNA metabolic processes such as replication stress response, double strand break repair (DSBR), mismatch repair, nucleotide excision repair and telomere maintenance. Both Mre11 and Exo1 play a critical role in the DNA resection in DSBR. Mre11 is responsible for the initial short-range resection, which is followed by the long resection by Exo1 before strand invasion in DSBR. However, the regulation of this switch between Mre11 and Exo1 is not well understood. The purpose of this study is to test the hypothesis that EXO1 and MRE11 gene variants contribute to genomic instability by aberrant DNA repair. This project seeks to understand the potential role of disease-associated variants of Exo1 and Mre11 in defective resection function, thus inducing genomic instability

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