2045 research outputs found
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The Hungarian Radical Right and Holocaust Memory
Full text linkThis thesis studies the role of the Hungarian government\u27s museums, monuments, and speeches in supporting its nationalistic narrative of twentieth century history and its contemporary policies. It brings together history of the interwar period, the Second World War, the Holocaust, and Hungarian communism
If You’re Happy, I’m Happy. How Levels of Self-Satisfaction Affect Selfless Love
Full text linkDoes personal satisfaction with oneself impact one’s ability to put the happiness of others before their own? I hypothesize that individuals who have higher levels of self-satisfaction are less likely to practice selfless love. In this study, “self-satisfaction” is interpreted as a person’s contentment with self. “Selfless love,” which is synonymous with altruistic love, is interpreted in this study as a relationship in which one or both partners prioritize the needs of their partner before themselves. To test this hypothesis, I conduct a regression analysis (n= 667) from the 2004 General Social Survey (GSS), controlling for degree, income and gender. Results from bivariate and multivariate regression indicate that there is no statistically significant relationship between self-satisfaction and selfless love, contrary to the hypothesis. However, two of the control variables influence the dependent variable within this study. Gender has the strongest effect on selfless love, followed by level of completed education: women and those with higher levels of completed education are more likely to engage in acts of selfless love
I Have My Degree, Now I Want a Ring: The Link Between Educational Attainment and a Happy Marriage
Full text linkThe research reported here used measures of educational attainment and happiness of marriage to assess how happy college educated women are in their marriages relative to their non college educated counterparts. A regression analysis of data from the 2018 General Social Survey American indicated that there is no link between marital happiness and degree attained based on gender. The greatest indicated likelihood of being in a happy marriage of the highest quality is among those who are white identifying people, net of the estimated effects of time since first marriage and several variables that might commonly affect marital happiness such as sex, age and race. The non-significant relationship between the degree variable and happiness of marriage can be due to many factors but it would be premature to conclude that there is absolutely not relationship between degree and happiness of marriage, especially given the existing scholarship. However, the findings do suggest that white people are more likely to say they are very happy in their marriages, pursue and attain a college education, and are older compared to their counterparts. These results are very telling of one of many socially constructed institutions that benefits white individuals and provides more advantages that increase the chances of marital success and happiness
Blood-Ties and Misfortune
Full text linkA story about a boy who faces familial and mental health struggles
Verity
No full textA divorced, despondent middle school science teacher joins a secret society and helps them get to the bottom of a Galapagos tortoise government conspiracy
Learning by Doing, by Wondering, by Figuring Things Out: A New Look at Contemporary Homeschooling and Pedagogical Progressivism
Full text linkPedagogical progressive education, as defined through the work of John Dewey, Helen Parkhurst, and Carleton Washburne was the precursor to the contemporary homeschooling movement in ideology, practice, and rhetoric as defined by the writing and pedagogy of John Holt. Their shared beliefs in community, student freedom, and good experience as pertinent to education marked the relationship between these two pedagogical methods. Despite Holt\u27s departure from the classroom through his unschooling method, the ideological consistencies between the movement are undeniable, suggesting we rethink the relationship between progressive education and homeschooling and our basic assumptions about the legacy of both movements
States of Fear: The Rise of the European Alt-Right Through the Eyes of Immigrant Populations
Full text linkThis research explores the rise of alt-right groups in Europe through a case study approach with a focus on Spain as well as a general approach focused on Europe as a whole. For the case study, blog posts from the Spanish female-immigrant centered forum, Afroféminas, were analyzed. To provide evidence from the broader European context while still centering immigrant and refugee voices, the PBS Frontline documentary film Exodus: The Journey Continues was utilized. Through the use of discourse analysis as well as theoretical grounding in Giddens’ structuration and Bourdieu’s praxeology, this research presented two main findings: (1) it is possible to see a strong “us vs. them” dichotomy between alt-right groups and immigrant/refugee groups, which is perpetuated through its continued use, and (2) strong emotions and fear can be seen as a factor which both divides and unites alt-right and immigrant/refugee groups in their struggles for a place and voice within society as a whole
Confronting Whiteness in the Teacher Education Classroom
No full textWho is hired as teachers has a big impact. Kenneth Sider, visiting assistant professor at Skidmore College, explains why.https://creativematter.skidmore.edu/academic_minute/1002/thumbnail.jp
Proline Omega Angle Cis-Trans Isomerization in ArkA12 Using Enhanced Molecular Dynamics
No full textArkA12 is a proline rich intrinsically disordered protein (IDP) region within a larger, more structured, non-tyrosine kinase (ArkA). The disordered region binds to the AbpSH3 domain due to the domain’s high affinity towards PxxP motifs within the substrate. SH3 domains are numerous in the human genome and are largely responsible for cytoskeleton regulation, signal transduction, and gene expression. A binding mechanism for ArkA12 and AbpSH3 has only recently been elucidated via atomistic computer simulations: depicting ArkA12 in a predominately polyproline II helical structure in the fully bound state, with all five prolines in the trans conformation and no isomerization. The structure of the proline side chain allows peptide bonds to sample between the cis and trans states more readily than the other common amino acids. It is difficult to capture the peptide bond isomerization utilizing classical experimental and computational methods due to the characteristic rapid conformational switching in IDPs, as well as the proline isomerization rates occurring on the order of seconds, making it improbable to detect with the current technology. Multiple proteins have evolved to use proline isomerization as a “switch” for processes requiring quick turnaround times such as gene regulation.
Current experimental circular dichroism data of ArkA12 suggests that the in vitro ensemble may be composed, in part, of structures that contain prolines in cis; reinforcing the need to represent this kind of sampling in the computational data to ensure that the computational ensemble is complete, increasing the likelihood of the data accurately complimenting experimental results. There is currently no data in the literature that has observed proline peptide bond isomerization in proteins of lengths larger than ~5 residues, even with enhanced methods. Computational methods that were able to capture the cis conformation used programs that relied heavily on statistical probability calculations which do not subject conformational ensembles to a primarily time-dependent simulation trajectory: complicating the ease and feasibility of comparing the data to experiments, as well as increasing the likelihood of observing wider deviations from the experiments. The same studies only used peptides containing a single proline or peptides with more than one proline with only one proline captured isomerizing. The largest hinderance to sufficient isomerization sampling is the time that the proline peptide bond requires to flip; this means that the free energy barrier between the cis and trans states may be programmed to be too large in the common molecular dynamics forcefield, thus highlighting the need to counteract the default forcefield effects to accelerate sampling.
The current work uses the gaussian accelerated molecular dynamics algorithm along with a modified peptide torsional angle barrier in the Amberff14SB force field to artificially lower the potential energy landscape to promote faster and more diverse structure sampling. Two microseconds of independent simulation data showed simultaneous cis-trans isomerization for all five prolines in ArkA12 starting from an extended structure. Calculating the theoretical circular dichroism spectrum of the computational ensemble and comparing it to the experimental spectrum can possibly be used to decide whether cis sampling occurs for ArkA12 in vitro, as well as confirm whether the sampling method yields a closer fit to the experiments compared to non-modified sampling methods. The results suggest that this gaussian accelerated-lower barrier computational method can be used to sample proline cis-trans isomerization for similar proline-rich IDPs at the nanosecond timescale without implicitly facilitating certain trajectory processes that may compromise the data’s relevancy to the experimental results
Study of 4-Benzoylbenzoic Acid as a Proxy of Environmental Photosensitizers
No full textSea-spay aerosols (SSA) released from the marine boundary layer (MBL) through wave breaking and bubble bursting contain marine chromophoric dissolved organic matter (m-CDOM). These complex substances can act as photosensitizers of atmospheric trace gases, opening previously unrecognized chemical reactions within SSA. Previous studies seeking to replicate the optical and photochemical properties of m-CDOM have used small molecules, such as pyruvic acid, to simulate m-CDOM. This work proposes an additional photosensitizer, 4-benzoylbenzoic acid (4BBA), to introduce the effects of aromaticity and low solubility. The pH dependent speciation and optical activity of 4BBA was studied experimentally and theoretically, yielding excellent agreement. Photoexcitation of 4BBA within the solar spectra is shown to catalyze indirect mass transfer and oxidation of nonanoic acid, a proxy fatty acid found in SSA. As m-CDOM can likely only be modeled by a combination of several molecules, this work offers an additional aromatic and low solubility chromophore towards a complete model of m-CDOM