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Hybrid Renewable Energy Systems: Design and Performance: Towards EU target for nearly zero energy buildings from 2020
Get PDFEnvironmental Sustainability Assessment Methodologies for Steel and Timber Structures
Get PDFThe current research investigates the main environmental sustainability assessment methodologies
for steel and timber structures in order to determine their potential in terms of effectively displaying the
sustainability characteristics of the two construction technologies. The main types of assessment methodologies are cross-checked with a series of key issues such as recycling, reuse, waste, ease, speed and accuracy of construction and the wide variety of projects that can be constructed as steel or timber structures. Conclusions concerning the purpose of application of each type of assessment are drawn
Επίδραση του επιπέδου πείνας στη λειτουργική απόκριση του αρπακτικού Macrolophus pygmaeus = Εffect of hunger level on functional response of the predator Macrolophus pygmaeus
No full textWestern Greece and Ionian Sea petroleum systems
Get PDFIn western Greece, the Ionian and pre-Apulian zones represent, respectively, the basin and the transitional zone (slope) to the Apulian platform. The Apulian platform constitutes the weakly deformed foreland of the external Hellenides. The pre-Apulian zone appears in the Ionian Islands and the eastern Ionian Sea, whereas the Apulian platform is exclusively found in the Ionian Sea. The Ionian zone consists of Triassic evaporites, Jurassic–upper Eocene (mostly pelagic carbonates, minor cherts, and shales), overlain by the Oligocene flysch. Organic-rich source rocks occur within Triassic evaporites and Jurassic–Cretaceous pelagic argillaceous-siliceous rocks. The pre-Apulian zone consists of Triassic to Miocene deposits, mainly mixed neritic-pelagic carbonates. Hydrocarbon source rocks include pelagic and hemipelagic deposits rich in marine organic material, although terrigenous organic matter is also found in siliciclastic layers. Apulian platform source rocks are mainly the organic-rich shales within the Triassic Burano evaporites. Western Greece contains major petroleum systems, which extend into the Ionian Sea. Ionian, pre-Apulian, and Apulian petroleum systems contribute to the probable hydrocarbon accumulations within the big offshore (Ionian Sea) anticlines. Western Greece contains important oil and gas shale reservoirs with a potential of unconventional exploration. Promising areas for hydrocarbons need systematic and detailed three dimensional seismic data. Exploration for conventional petroleum reservoirs, through the interpretation of seismic profiles and the abundant surface geologic data, will provide the subsurface geometric characteristics of the unconventional reservoirs. Their exploitation should follow that of conventional hydrocarbons to benefit from the anticipated technological advances, eliminating environmental repercussions
Μελέτη δράσεων δικτύωσης ΔΑΣΤΑ
No full textΟι δράσεις δικτύωσης και διασύνδεσης της ΔΑΣΤΑ ΑΣΠΑΙΤΕ με άλλα εκπαιδευτικά ιδρύματα, φορείς και οργανισμούς που σχετίζονται με την απασχόληση, την αγορά εργασίας και την επιχειρηματικότητα, αποτελούν σημαντικό μέρος της δραστηριότητας τόσο της ΔΑΣΤΑ ΑΣΠΑΙΤΕ όσο και των υποστηριζόμενων από αυτή φορέων. Eιδικό ρόλο πρόκειται να διαδραματίσει η διασύνδεση με φορείς «κλειδιά» στην προώθηση των αποφοίτων στην αγορά εργασίας, όπως είναι τα Κέντρα Προώθησης της Απασχόλησης του ΟΑΕΔ και άλλοι πιστοποιημένοι φορείς προώθησης της απασχόλησης και σύζευξης της προσφοράς και ζήτησης της αγοράς εργασίας
The loss of the tumour-suppressor miR-145 results in the shorter disease-free survival of prostate cancer patients
Get PDFBackground: Prostate cancer (PCa) is characterised by great heterogeneity of the disease progression rate. Tumours range from insignificant and not life threatening to high risk for relapse ones. Consequently, a large number of patients undergo unnecessary treatment. miR-145 is a well-documented tumour suppressor and its expression, which is regulated by the p53 pathway, has been found to be decreased in the majority of human malignancies. The aim of our study was to evaluate the clinical utility of miR-145 for the prognostication of PCa.
Methods: Total RNA was isolated from 137 prostate tissue specimens obtained from 73 radical prostatectomy-treated PCa patients and 64 transurethral- or open prostatectomy-treated benign prostate hyperplasia (BPH) patients. Following polyadenylation and reverse transcription, miR-145 levels were determined by quantitative real-time PCR assay, using SNORD48 (RNU48) for normalisation purposes.
Results: Downregulated miR-145 expression was found in PCa compared with BPH patients. The reduction of miR-145 expression in PCa was correlated with higher Gleason score, advanced clinical stage, larger tumour diameter and higher prostate-specific antigen (PSA) and follow-up PSA levels. In addition, higher risk for biochemical recurrence and significantly shorter disease-free survival (DFS) was found for the PCa patients expressing lower miR-145. Focusing on ‘low- and intermediate-recurrence risk’ PCa patients, miR-145 loss was revealed to be a reliable predictor of biochemical relapse and poor DFS independent from Gleason score, clinical stage, PSA and patients’ age.
Conclusion: The loss of the tumour-suppressor miR-145 increases the risk for disease progression and predicts the poor survival of PCa patients