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Alhambra, Court of Lions
No full texthttps://digital.kenyon.edu/arthistorystudycollection/2818/thumbnail.jp
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No full textIn this piece, Hu has placed lights on top of an open-face book and below it hands a chaotic jumble of cables. The pages of the book are densely filled with texts, but the pages appear serene and inviting especially in contrast with the mess of cables. The artist may be attempting to contrast the two methods of communication: literary and electronic. She appears to be calling into question the myth that modern-day technology is more efficient than books. The piece has been left untitled. In Hu\u27s artist statement she says, The daily use, of common products obscures the inner meaning of their existence, I am interested in the crystal-clear of the glass, the industrial hardness poses a challenge since I was working with things of soft sogginess before . (Nicole Wang \u2726).https://digital.kenyon.edu/zhou/1688/thumbnail.jp
Associations Between Social Determinants of Health & Intrapatient Variability in Tacrolimus Levels for Children Post Hematopoietic Stem Cell Transplant
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When “Do No Harm” and “Child Protection” Conflict: Assessing Drug Screening and Reporting Practices Among Ohio Healthcare Providers
No full textThis study qualitatively examines Ohio reproductive care providers’ understanding of legal requirements, institutional protocols, and workplace norms surrounding informed consent, toxicology screening, and CPS reporting and assesses the extent to which these providers have interacted with law enforcement in their jobs. Our online data collection is currently in progress, which will be analyzed by three coders. Through this process, we will identify common themes in providers’ care regarding substance-using patients, experiences with law enforcement in their workplaces, and develop recommendations for safeguarding confidentiality and family well-being in Ohio
Determining the role and necessity of mecr in Caenorhabditis elegans
No full textRecessive mutations to the gene MECR lead to Mitochondrial Enoyl-CoA Reductase Protein-Associated Neurodegeneration (MEPAN) syndrome, a rare mitochondrial disease. MECR is part of the mitochondrial fatty acid synthesis II (mtFASII) pathway, reducing the last step of the pathway to produce acyl chains of varying lengths that include precursors of essential cofactors for proteins in most stages of cellular respiration. Deletion of mecr-1, the Caenorhabditis elegans MECR ortholog, significantly shortens lifespan, leads to smaller germlines, and produces germline defects that result in near complete sterility. Contrary to our predictions, the transition zone—the area where undifferentiated germ cells transition from mitosis to meiosis—of mutant worms was smaller than wild type (WT). Germ cell proliferation rates were also decreased, although proliferation unexpectedly occurred in the primary spermatocytes. While the mechanism of germline dysfunction is unclear, we predict RNA binding proteins (RBPs, e.g. GLD-1/LIN-41) involved in the development of germ cells are impaired as our findings are phenotypically similar to RBP mutants. In addition to investigating the germline defects of mecr-1, we have also investigated its C. elegans paralog, mecr-2, whose function is unknown. We hypothesized that mecr-2 would not be necessary, which we tested with lifespan and brood size assays and western blot analysis of lipoic acid (LA) production, the canonical mtFASII product. We found no significant difference between the lifespans or brood sizes of mecr-2 knockout worms and WT, indicating that mecr-2 is not necessary in the presence of mecr-1. However, mecr-1 and mecr-2 mutant strains presented unexpected patterns in LA production, including the retention of LA despite impairment of mtFAS which is the only known pathway through which LA is produced. The observed LA production suggests that there is an unknown mechanism of LA production in C. elegans. In all, we found that mecr-1 mutants have severe germline defects while mecr-2 mutants do not appear to be impaired
Spot the Differences: A Multivariate Exploration of Frontal-Midline Theta Power
No full textSeveral cognitive tasks, such as cognitive control and episodic memory, have been associated with frontal-midline theta (4-8 Hz) power. However, it is unclear if the theta power observed at this location across tasks is due to task-specific or common cognitive mechanisms. The traditional local approach of analyzing one or two frontal-midline electrode sites potentially excludes information distributed across the scalp that might help clarify this question. To address this limitation, the current study uses multivariate classification to investigate the distributed patterns of theta across the scalp during both a cognitive control and an episodic memory task. Consistent with prior reports, significant differences in theta power were observed at frontal-midline sites for both cognitive tasks. Importantly, conditions were also successfully differentiated within each task using theta oscillations from every electrode across the scalp in multivariate classification. However, multivariate cross-classification between tasks was unsuccessful. These results suggest that the frontal-midline theta observed in both cognitive control and episodic memory tasks does not reflect engagement of a common cognitive process. Rather, differences in frontal-midline theta power is part of a unique global response associated with each task