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The Victorian Women Writers Project
No full textA talk on the collaboration and cooperation that happened between the English department and the library leading up to the impending Scholars' Commons at the University of Indiana
Implementation of the 2010 Ohio Nursing Home Family Satisfaction Survey: Final Reportf
Get PDFIn 2010, the Scripps Gerontology Center conducted the fifth biennial Ohio Nursing Home Family Satisfaction Survey under a contract to the Ohio Department of Aging. This year the survey had the largest number of family response ever, with 97% of facilities participating and nearly 30,000 involved family and friends responding. An online version of the family survey was also made available for the first time. The report includes information about the survey process, psychometric analysis of the survey, and recommendations for future implementation of the family survey. The family satisfaction survey is one important component of the comprehensive nursing home information shown on the Ohio Long-Term Care Consumer Guide (www.ltcohio.org). Overall scores are also used as a quality component of Ohio's nursing home Medicaid reimbursement formula
An Edgeless, Honest Kid: A Collage of Memoir, Manifesto, and Other Musings
No full textThis is a collage project that uses multiple genres of creative writing to express my emotional and psychological arc while at Miami University
Evaluating Transit-Oriented Development Effectiveness
No full textAs resources become scare, transportation costs rise, and congestion gets worse, developing transit alternatives will become increasingly important. Transit-oriented development is a sustainable method for building communities that are less dependent on the automobile. Methods for evaluating the potential and effectiveness of a transit-oriented development include determining an area’s vehicle miles traveled, normative characteristics, and a spectrum from transit-adjacent to transit-oriented. The purpose of this paper is to outline a method to evaluate the pedestrian-orientation of transit stations that can augment existing methods of measuring the characteristics of transit-oriented developments. The case study of the transit zone surrounding the Harlem/Lake El Station in Oak Park, Illinois is used to demonstrate the utilization of this method. The study area includes North Marion Street, the Pleasant District and the proposed Chelsea Station developments
How OPEN SCHOLARSHIP is CHANGING RESEARCH
No full textA talk about how new digital capabilities -including electronic publishing, social media, institutional repositories, and copyright legislation- are profoundly impacting traditional scholarly communication
Temporal aspects of Ciliary Neurotrophic Factor on the Suppressor of Cytokine Signaling 3 Expression and the JAK/STAT Pathway in Rat Retinal Müller cells
No full textThe cytokine ciliary neurotrophic factor (CNTF) is a neuroprotective agent in the central nervous system. CNTF activates the JAK/STAT signaling pathway to induce protein expression, which subsequently levels off due to negative control. One class of negative regulators is the suppressors of cytokine signaling (SOCS) proteins. The goal of my research was to study the temporal aspects of CNTF on SOCS3 gene expression and its relationship to the JAK/STAT pathway; and examine the effects of CNTF on levels of other proteins involved in the JAK/STAT pathway.
Retinal Müller cells were treated with CNTF for different time periods from 0 to 90 minutes. The total RNA collected was converted into cDNA for use in quantitative real-time PCR. At 15 minutes, the CNTF-treated cells showed a 2.5 fold increase in SOCS3 mRNA, which increased to 3.5 fold by 30 minutes. The level of SOCS3 mRNA returned to baseline by 90 minutes.
A separate set of cells were transfected with a dominant-negative STAT3 mutant prior to the treatment with CNTF at different time periods from 0 to 90 minutes. The total RNA collected was converted into cDNA for use in quantitative real-time PCR. The dominant-negative STAT3 mutant appears to negate up-regulation of SOCS3 in response to CNTF. These experimental results indicate SOCS3 as a negative feedback regulator of CNTF activation of the JAK/STAT pathway.
CNTF-treated cells were analyzed using Western immunoblotting techniques to study the levels of other proteins such as P-AMPK, P-MAPK, and P-AKT that are involved in the JAK/STAT pathway. There were no significant changes in levels of P-AMPK and P-AKT over 90-minutes. A large increase in the level of P-MAPK was observed at 15 minutes and a substantial decrease was observed at 30 minutes. The P-MAPK level returned to baseline by 60 minutes. The role of P-MAPK in the JAK/STAT pathway of retinal cells is under further investigation
"Going to the Mountains is Going Home": Constructing Early Twentieth-Century American Wilderness and National Parks
No full textThe interest for this thesis stemmed from existing critical discussions of the difference between the landscapes demarcated by the words “wilderness” and “wildness.” For example, in Walden, Henry David Thoreau pointedly uses the word “wild,” rather than “wilderness” to describe his surroundings at Walden Pond. This sparked critical discussions about the landscape of mid-nineteenth century Massachusetts, and the ways in which that landscape would or would not qualify as “wilderness.” This thesis, then, takes up similar questions: What is the difference between “wildness” and “wilderness?” Can “wilderness” be given a concrete definition, or is the definition always changing based on cultural viewpoints? How do national parks protect “wilderness?” Or, do they even protect “wilderness” at all? The thesis then moves into an interdisciplinary approach toward attempting to understand the American fascination with wilderness and the American relationship with national parks that stems from that fascination.
In order to make an attempt at answering these questions, this thesis incorporates three areas of historical research, before bringing all lines of research together into a final argument. The first section looks at the history of “wilderness” as a cultural concept: the development of the word and its connotations in Europe, the ways in which the word was applied to the American landscape as immigrants from Europe settled in North America, and the ways in which the understanding of “wilderness” has changed into an idealized form. The second section considers the history of American national parks, and how tourism has functioned in the process of creating the national parks. Then, the third section examines the government documents that created the National Park Service in 1916, and the ways in which the creation of the National Park Service changed both American national parks and the American “wilderness” ideal. Finally, the last section brings these lines of inquiry together in a study of 1916 issues of the Saturday Evening Post, National Geographic, and Harper’s Weekly, which give insight into the ways in which the American public regarded wilderness and national parks at the time of the establishment of the National Park Service