The University of Texas at Tyler
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Spatial scenery of congenital syphilis in Brazil between 2007 and 2018: An ecological study
Get PDFObjective: To analysis the epidemiological scenery of the congenital syphilis (CS) in Brazil employing spatial analysis techniques. Design: Ecological study. Settings: This study was conducted in Brazil Sample: A total of 151 601 CS cases notified to the Diseases and Notification Information System from 2007 to 2018 from children aged 0–23 months and born from mothers living in Brazil were included in this study. Primary outcome measures: The CS incidence rates were calculated by triad (2007–2010, 2011–2014 and 2015–2018) for all Brazilian municipalities following the Boxcox transformation to remove the discrepant values. The transformed rates were analysed through the spatial autocorrelation of Moran, Kernel density estimative and spatial scan. Results: From 2007 to 2018, the CS incidence rates increased in all Brazilian regions. The CS spread towards the interior of Brazil, and a higher expansion was noticed between 2015 and 2018. The municipalities that were greatly affected by the CS were those having a high migration of people, such as the ones bordering other countries and the touristic cities. Recife, Campo Grande, Rio de Janeiro, Porto Alegre and Manaus were the capitals with the greatest spatial and spatiotemporal risk. Conclusion: This study provides assistance to health authorities to fight CS in Brazil. More investment is necessary in prenatal care quality focusing on pregnant women and their partners to guarantee their full access to preventive resources against sexually transmitted infections
Inflation Reduction Act: The Five-Minute Version
Get PDFIn this issue of the Hibbs Brief, we discuss key elements and possible future effects of House Bill 5376, better known as the Inflation Reduction Act (IRA). We will provide an overview of the bill along with an analysis from various agencies on the bill’s predicted effects over the next 10 year
The Tyler Outlaws & African American Baseball
Get PDFPhotograph of the Tyler Outlaws baseball team with a brief history of African American baseball in Smith County, 1883-1949
Panel Presentation: Research, Innovation, Entrepreneurship in Pharmaceutical Sciences
No full textSantosh Aryal, PhD - Recent Advances In Nanomedicine And Its Applications In Diagnosis And Therapy
Joe Glavy, PhD - Viral Transport Through the Nuclear Pore
Ayman Hamouda, PhD., and Brittany L. Parmentier - PharmDCannabidiol (CBD) Use in East Texas and Product Analysi
Appointment Reminder System Benchmark Study
Get PDFThe average appointment “no-show” rate is 23% across 105 studies (Dantas et al., 2018). These “no-shows” cost an estimated 150 billion dollars a year to the American healthcare industry (Ruiz-Hernandez et al., 2020). Previous estimates place the cost of one no-show event at a primary office in the range of 274 (Aysola et al., 2020). These missed appointments not only cause a loss in office revenue, but also harm the patients missing the appointment (Marbouh et al., 2020). Some of the repercussions patients suffer from are longer wait times for appointments, higher Emergency Room (ER) admission rates, and discontinued care processes (Marbouh et al., 2020). Missed appointments also create dissatisfaction in patients, disruption in continuity of healthcare services, and impedes the identification and treatment of diseases (Ullah et al., 2018).
Decreasing “no-shows” is essential to boost revenue, patient satisfaction, and decrease patient harm. When Kumthekar & Johnson (2018) conducted their pilot survey prior to their study the most common reason for missed appointments was that the patient forgot about the appointment. To fix any problem it is essential to find the root cause. Though not all patients are missing their appointments due to forgetting, adding a text or call appointment reminder system to the primary care office will help solve this problem.
With the addition of the appointment reminder system it is to be expected that “no-shows” and missed appointments will decrease. The decrease in “no-shows” will decrease wasted time at the primary care practice. Revenue should improve due to the decrease in abrupt open appointment slots. The increased revenue will be over what is needed to cover the cost of the appointment reminder system
Health Literacy in Acute Care Benchmark Study
Get PDFPoor health literacy levels directly correlate to poor patient discharge adherence and to an increase in repeat emergency department visits and healthcare costs. In addition, poor health literacy levels are directly correlated to a decrease in patient health outcomes. Studies clearly demonstrate that determining patient health literacy levels can be used to develop appropriate discharge instructions and education that will improve patient adherence and health outcomes, thus reducing emergency department readmissions and healthcare costs.
The purpose of this benchmark project is to implement procedures for consistently obtaining patient health literacy levels, along with language preferences, using the HLS-SF12 and to initiate processes to structure discharge instructions and education according to scored patient health literacy levels. The goal is to improve patient health outcomes, lower healthcare costs, and reduce avoidable emergency room visits
Central line associated blood stream infection (CLABSI) Prevention through Designated-Nurse peripherally inserted central catheter (PICC) line Dressing Change
Get PDFThe goal of this review is to show ways in which a nurse can have influence in the patient’s life by caring for their PICC line. The rate of hospital-acquired infections is related to the care that patients get while admitted in the hospital. All hospital acquired infections can and should be prevented. This is also true for central line associated blood stream infections (CLABSI). The care provided to a patient with a PICC line, including how their line is taken care of, decides if the line gets infected, and if the patients get an infection. When patients get a PICC line infection kwon as CLABSI, some patients end up getting extremely sick and this could even result to death. According to Perin et al (2016), about 250-500,000 CLABSI’s are estimated to occur each year, resulting in about 10-30% mortality rate. In research from Ziegler et al, CLABSI is associated with a high mortality rate. This, therefore, calls for the need for intervention efforts to aid in preventing CLABSI. Prior research has been conducted on ways in which to prevent this infection, but more research needs to occur so that more nurses can be involved in the prevention effort of CLABSI. Prior intervention efforts have been hand washing, use of Chlorhexidine, use of nurse designated PICC teams. More research could involve studies in which nursing, as a department, works in collaboration with the infection control team to prevent central catheter associated bloodstream infections. My project would fill this gap in research. I propose that by forming teams of nurses, where designated nurses change PICC line dressings weekly and maintain them would help reduce CLABSI
DNP FINAL REPORT: USING STANDARDIZED SURGICAL BUNDLES TO REDUCE POST CESAREAN SECTION INFECTION: AN EVIDENCE-BASED PRACTICE PROJECT
Get PDFA new mother has so many stressors and a post cesarean section infection should never have to be one of them. The infection rate at MHTW is double the national average at 1.85. This evidence-based practice project looks at the implementation of a pre-surgical bundle in women undergoing cesarean section to reduce overall risk of developing a post cesarean section infection. This evidence shows that the combination of a standardized bundle including infection specific education for the patient and family, pre- and post-surgical bathing, elimination of jewelry worn by patients and staff, antibiotic timing, Chlorhexidine skin prep, and a vaginal prep are all linked to decreased post cesarean section surgical site infections. Six months after implementation of the standardized surgical site infection bundle the C/S infection rate at MHTW dropped to 0.28
Mitochondria-associated myosin 19 processively transports mitochondria on actin tracks in living cells
Get PDFMitochondria are fundamentally important in cell function, and their malfunction can cause the development of cancer, cardiovascular disease, and neuronal disorders. Myosin 19 (Myo19) shows discrete localization with mitochondria and is thought to play an important role in mitochondrial dynamics and function; however, the function of Myo19 in mitochondrial dynamics at the cellular and molecular levels is poorly understood. Critical missing information is whether Myo19 is a processive motor that is suitable for transportation of mitochondria. Here, we show for the first time that single Myo19 molecules processively move on actin filaments and can transport mitochondria in cells. We demonstrate that Myo19 dimers having a leucine zipper processively moved on cellular actin tracks in demembraned cells with a velocity of 50 to 60 nm/s and a run length of ~0.4 μm, similar to the movement of isolated mitochondria from Myo19 dimer-transfected cells on actin tracks, suggesting that the Myo19 dimer can transport mitochondria. Furthermore, we show single molecules of Myo19 dimers processively moved on single actin filaments with a large step size of ~34 nm. Importantly, WT Myo19 single molecules without the leucine zipper processively move in filopodia in living cells similar to Myo19 dimers, whereas deletion of the tail domain abolished such active movement. These results suggest that Myo19 can processively move on actin filaments when two Myo19 monomers form a dimer, presumably as a result of tail–tail association. In conclusion, Myo19 molecules can directly transport mitochondria on actin tracks within living cells