The University of Texas at Tyler

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    5042 research outputs found

    A Whole-Food Plant Based Diet and its Effects on Cardiovascular Disease

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    The purpose of this paper and benchmark study is to present evidenced-based data regarding the impact diet choices have on heart disease and how adherence to a whole food plant based (WFPB) diet compared to a Western diet affects cardiac disease. The PICOT question being asked for this change project is as follows: In adults with history of cardiac disease (P), how does adherence to a whole-food plant-based (WFPB) diet (I) compared to the Western diet (C) impact outcomes associated with coronary artery disease (CAD) (O) over three months (T)? A search of evidenced-based literature was conducted to determine the positive outcomes associated with abiding by a WFPB diet while living with heart disease

    Resuscitation of Hypovolemic Trauma Patients: Controlled /Hypotensive Resuscitation vs. Conventional Resuscitation

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    The manner in which clinicians have used to resuscitate hemorrhagic trauma patients has been a continuous repetitive cycle over time. The cycle has gone from “run the fluids wide open in the patient” to “less is more in the patient”. As more evidence-based practice (EBP) emerges, reasons for ‘less is more’ become acutely evident. Large fluid volume resuscitation is highly suspicious for the exacerbation of the lethal triad of trauma: hypothermia, acidosis, and coagulopathy, thereby increasing bleeding and mortality (Cotton et al., 2006). The increased risk of bleeding also worsens the complications associated with trauma resuscitation. This all creates a cascade of potential harmful effects to the patient including, but not limited to coagulopathy, pneumonia, acute respiratory distress syndrome (ARDS), acute renal failure (ARF), multi-system organ failure (MOF), sepsis, infection and in some cases, death. Each of these unwarranted complications has the potential to increase the length of hospital stay therefore increasing the overall cost of care to the patient. In a recent study by Scott, et al., trauma care costs are estimated at $163 billion per year (Scott et al., 2020). For clinicians who treat trauma patients, the objective should be to provide better, more up to date trauma resuscitation care which would lead to a reduction of complications for the patient and, in turn, a decrease in the cost of care for the patient. This project will optimistically help guide that practice

    Safe Patient Handling and Mobility Olympics

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    The focus of this study is the implementation of a Safe Patient Handling and Mobility (SPHM) program titled SPHM Olympics. The study reviews the necessary components and background necessary to implement the project as well as evaluation tools to monitor the impact of the program on the safety of culture at Houston Methodist West (HMW). The program originated from the SPHM committee’s need to improve the utilization of SPHM equipment and techniques by clinical staff throughout the hospital as evidenced by the substantial number of clinical staff suffering from musculoskeletal disorders and HMW clinical staff’s current views that SPHM techniques and equipment are too time consuming to utilize. The PICOT formatted question is in an acute care hospital (P), how does implementing a Safe Patient Handling and Mobility (SPHM) Awareness Program (I) compared to current SPHM Awareness initiatives (C) affect the hospital’s culture of safety regarding SPHM techniques and equipment utilization (O) over a one-month period

    AN INTEGRATED ELECTRONIC-SKIN PATCH FOR REAL-TIME AND CONTINUOUS MONITORING OF A PANEL OF BIOMARKERS COMBINED WITH DRUG DELIVERY

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    Inflammatory biomarkers present in the human body play a vital role in medical field by guiding the clinician in decision-making for many diseases. The levels of these inflammatory biomarkers are associated with the severity and progress of several diseases. Researchers have found that increasing severity of many diseases such as cardiovascular disease, after surgery infection, and adverse clinical outcomes due to infectious diseases, results in the elevation of the level of inflammatory biomarkers in human sweat. Furthermore, the inflammatory cytokines indicate the pathophysiology and prognosis of critically ill SARS‑CoV‑2 patients. In this thesis work, different sensors have been developed for the detection of inflammatory biomarkers, such as C-reactive proteins (CRP), Interlukin-6 (IL-6), and Interlukin-10 (IL-10) to enable real-time monitoring of the aforementioned disease conditions. These inflammatory biomarkers also provide valuable information on the wound healing progress. Hence, a wound monitoring sensor has also been fabricated in this thesis work for real-time monitoring and management of wound dynamics. Besides detection and monitoring the disease conditions, it is also necessary to provide controlled and on-demand drug delivery. Therefore, an electronically controlled drug delivery module was fabricated to deliver transdermal drug through the human skin. The developed sweat sensors detected the target analytes from a small amount of artificial sweat sample collected via a microfluidic channel that minimized the requirement of sweat sample, and reduced contamination and evaporation of sweat from the human skin. The microfluidicii channel collected the sweat from skin and directed the sweat flow to the main sensing region. In addition, a substantial amount of attention is needed to ensure the high-precision performance of wearable sensors irrespective of any body movements such as stretching, bending, and twisting motions. To achieve this, kirigami-patterned strain-insensitive sensors were integrated on a biaxially stretchable kirigami structure to quantitively measure sweat pH and temperature. The straininsensitive sensor depicted an excellent performance under biaxial tensile strain applied up to 220% and torsional strain up to 360°. Finally, tattoo sensors, fully conformal like a tattoo on the skin, were fabricated. In order to validate the performance of the tattoo sensor on a living cell, the temperature and humidity data were collected from live plants under both water-stress and unstressed conditions. All the sensors reported in this thesis have impressive performance with high sensitivity, accuracy, and low limit of detection (LoD), which are the expected parameters for every sensor. The sweat sensors fabricated in this thesis depicted an excellent combination of flexible structure, cost-effective fabrication, skin conformity, and high linearity of response that make our devices introduce a promising new route in the healthcare application of skin-inspired wearable sweat sensors

    Impact of Critical Incident Debriefing on Nursing Stress, Burnout, and Retention

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    Incorporating debriefing periods after critical incidents could alleviate the stress and emotional burden, yet many hospitals fail to implement debriefing. This project\u27s scope is to implement debriefing sessions after critical events using a debriefing tool. When creating a policy, it is essential to look at the preferences and values of those it aims to help. Forty-three percent of hospital nurses experience emotional exhaustion symptoms (Reith, 2018). There is a critical shortage of healthcare professionals that has only grown since the pandemic. Therefore, it is vital that hospitals set up an individualized debriefing tool that staff will use to help aid in debriefing post-critical events with a goal of reducing staff burnout, turnover rates, and the financial burden on the organization. The aim of this project is to answer the following PICOT: In new graduate nurses (P), how does critical incident debriefing (I) compared to no debriefing at all (C) affect burnout and retention (O) within the first six months of nursing(T)

    A MINIATURE AND LOW-POWER POTENTIOSTAT FOR INTEGRATION WITH WEARABLE SENSORS

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    The potentiostat is an analytical device and an important part of an electrochemical instrument commonly used in electrochemical experiments to investigate chemical reaction mechanisms and other chemical phenomena. The ability to detect chemical phenomena can be useful for early disease detection. Nowadays conventional potentiostats are designed as benchtop instruments for use in laboratory environments. In contrast, a wearable potentiostat is designed to interface with wearable biochemical sensors for disease diagnostics. This thesis reports a wearable potentiostat that is designed for interfacing with a sensor array (eight to ten working electrodes). The system is battery-powered using lithium-ion batteries. The data is transmitted to the user using a Bluetooth communication link. The entire system is controlled by a single Advanced RISC Machines (ARM) M4 microcontroller with an integrated Bluetooth low-energy radio module (Silicon Labs EFR32BG13 SoC). This work reports on the performance of the designed potentiostat in terms of accuracy, reliability, and power efficiency. The performance of the potentiostat is compared with the existing commercial benchtop potentiostat devices. Also, this work identifies further steps that will lead toward circuit miniaturization and further power efficiency improvements which will allow the manufacturing of wearable sensing devices comparable to the size of a wristwatch

    THE COPTIC ORTHODOX CHURCH: THE BALANCE OF ITS CONTINUATION OF ITS 1ST CENTURY ROOTS AND ITS ADAPTATION TO MODERNITY

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    This thesis analyzes the survival of the Coptic Orthodox Church and argues that the Church has effectively adapted to modernity. This survival and adaptation of this 1st century Church is argued for in the transformation and adaptation of language, the role of women, the practices of Coptic monasticism, and the creation of a new modern phenomena, the Coptic diasporic community, mainly though the example of the United States. The analyses presented are drawn from both primary and secondary sources that effectively ague for both the survival and adaptation of the Coptic Church. Finally, this thesis thus provides an institutional history of the Coptic Church while offering insights into its tradition, cultural practices, social structures, and transformations over time

    TRAUMA-INFORMED CARE IN NURSING CURRICULA: DEVELOPMENT OF A SIMULATION-BASED EDUCATIONAL FRAMEWORK TO GUIDE HEALTH PROFESSIONS

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    Individuals of all ages, genders, social and ethnic backgrounds, and cultures suffer traumatic experiences. Trauma does not discriminate. The immense number of individuals struggling with trauma requires that health care providers approach patient care through a trauma-informed lens. Trauma-informed care is an evidence-based approach to patient-centered care and is vital to the healthcare provider-patient relationship. The increased responsibility of healthcare providers to provide trauma-informed care to all individuals demands a scientifically-based framework to guide the development of a trauma-informed health care professions education program. Healthcare simulation allows health professions’ students to experience real-life scenarios in a safe setting before transitioning to practice. Currently, there are no simulation-based frameworks to guide health professions educators to train these students. This Delphi study established the framework for a comprehensive, trauma-informed, multidisciplinary health professions simulation framework to improve the delivery of trauma-informed care to traumatized patients. The findings provide content and sub-content areas for health professions student education from a multidisciplinary panel of subject matter experts. One manuscript was published in the Nursing Forum journal (Impact Factor 1.89) concentrating on the conceptual analysis of trauma-informed care. The second manuscript provided an integrative literature review of nursing curricula and trauma-informed care. Each of the two manuscripts established the foundation for this study

    IoT-Enabled Integrated Smart Wound Sensor for Multiplexed Monitoring of Inflammatory Biomarkers at the Wound Site

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    Chronic wounds that stall at the inflammatory phase of healing may create several life threatening complications such as tissue damage, septicemia, and organ failures. In order to prevent these adverse clinical outcomes and accelerate the wound healing process, it is crucial to monitor the wound status in real-time so that immediate therapeutic interventions can be implemented. In addition, continuous monitoring of the wound status can prevent drug overdose at the wound site, leading to on-demand and personalized drug delivery. Inflammatory mediators, such as Interleukin-6 (IL-6) and Interleukin-10 (IL-10) are promising indicators for the progression of wound healing and predictors of disease severity. Toward this end, this work reports a flexible wound patch for multiplexed monitoring of IL-6 and IL-10 at the wound site in order to provide real-time feedback on the inflammation phase of the wound. An optimized composition of gold nanoparticles integrated multiwalled carbon nanotube was demonstrated to improve sensor performance substantially. The sensor also exhibited excellent repeatable, reversible, and drift characteristics. A miniaturized Internet-of-things (IoT)-enabled potentiostat was also developed and integrated with the flexible sensor to realize a wearable system. This IoT-enabled wearable device provides a smart and cost-effective solution to improving the existing wound care through continuous, real-time, and in-situ monitoring of multiple wound biomarkers

    The 1930s: The Decade that Changed Tyler.

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    A photographic look at Tyler and the changes brought about by the East Texas Oil Boom

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    Scholar Works at UT Tyler (University of Texas at Tyler)
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