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Wellness Beyond Campus Walls: How Walking Worldwide Brought One Institution Together
No full textBackground: Investment in campus recreation has well-documented benefits, and the need for improved health and wellness also extends beyond students. Creating a campus culture that values health and well-being can be transformative for the health of the overall community.Aim: This study aimed to understand the impact of an institution-wide, 42-day virtual fitness initiative that included faculty, staff, students, and graduates. Methods: Participants were invited to complete two surveys (pre-and-post) consisting of questions about physical fitness, goal setting, and connection to the college community. Throughout the duration of the program, participants logged their physical activity (e.g., step counts) through a web-based platform.Results: Survey respondents reported exercising a greater number of days each week during the program and were more likely to set and achieve their fitness goals. The leading unexpected benefit of participation in the program, especially among our graduates, was developing social connections with other participants. Conclusions: Institution-wide fitness programs can promote health awareness and motivate faculty, staff, students, and graduates to improve fitness and connect socially
Loading-Dose Dupilumab May Function as a Prophylactic Agent for Food-Induced Anaphylaxis: A Case and Review of the Literature
No full textRecent advances in targeted therapy using monoclonal antibodies have revolutionized care in many fields, and dupilumab for the treatment of moderate-severe atopic dermatitis is no exception. While on a trial of loading dose dupilumab, a 25-year-old white male with a past medical history significant for anaphylaxis after ingesting peanuts and tree nuts did not experience anaphylaxis after accidentally consuming almonds. Similarly to anti-IgE, the large-scale inhibition of IL-4 and IL-13 signaling to various immune cells involved with type II hypersensitivity reactions using loading dose dupilumab may have played a role in preventing anaphylaxis in this patient. The role of loading dose dupilumab as a potential prophylactic agent against food-induced anaphylaxis could be explored cautiously as a novel way to reduce both morbidity and mortality in patients with these allergies
Exploring the Hand in Hands-On Learning: Illuminating the Standards for Mathematical Practice
No full textExploring the diverse sizes and shapes of hands among sixth-grade students offers a practical platform for engaging with complex mathematical concepts. This study involved 113 students who investigated the area of their hands, a task that requires understanding the measurement of irregular shapes. Traditionally, middle school curricula focus on the area of regular figures, such as squares and triangles. Addressing the grades 6-8 Measurement Standard, our activity introduces methods for calculating the area of more complex shapes. We detail the instructional activities used to familiarize students with these techniques across five sixth-grade classes. The hands-on approach not only aligns with best practices in mathematics education but also enriches students' problem-solving skills
Detectability of Varied Hybridization Scenarios Using Genome-Scale Hybrid Detection Methods
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Hybridization events complicate the accurate reconstruction of phylogenies, as they lead to patterns of genetic heritability that are unexpected under traditional, bifurcating models of species trees. This phenomenon has led to the development of methods to infer these varied hybridization events, both methods that reconstruct networks directly, as well as summary methods that predict individual hybridization events from a subset of taxa. However, a lack of empirical comparisons between methods – especially those pertaining to large networks with varied hybridization scenarios – hinders their practical use. Here, we provide a comprehensive review of popular summary methods: TICR, MSCquartets, HyDe, Patterson’s D-Statistic (ABBA-BABA), D3, and Dp. TICR and MSCquartets are based on quartet concordance factors gathered from gene tree topologies and HyDe, Patterson’s D-Statistic, D3, and Dp use site pattern frequencies to identify hybridization events between sets of three taxa. We then use simulated data to address questions of method accuracy and ideal use scenarios by testing methods against complex networks which depict gene flow events that differ in depth (timing), quantity (single vs. multiple, overlapping hybridizations), and rate of gene flow (γ). We find that deeper or multiple hybridization events may introduce noise and weaken the signal of hybridization, leading to higher relative false negative rates across all methods. Despite some forms of hybridization eluding quartet-based detection methods, MSCquartets displays high precision in most scenarios. While HyDe results in high false negative rates when tested on hybridizations involving extinct or unsampled ghost lineages, HyDe is the only method able to identify the direction of hybridization, distinguishing the source parental lineages from recipient hybrid lineages. Lastly, we test the methods on a dataset of ultraconserved elements from the bee subfamily Nomiinae, finding possible hybridization events between clades which correspond to regions of poor support in the species tree estimated in a previous study
Exploring Hyperbolic Geometry
No full textThe author describes an investigative approach to some basic concepts of hyperbolic geometry for high school students. As undergraduate students, most teachers have had a proof-based understanding of hyperbolic geometry. With the use of WebSketchpad, a free on-line dynamic geometry application, students and teachers can experiment with ideas from hyperbolic geometry that lay a foundation for the proofs
More of the Story: Ruminations on “How Mathematics Education in Ohio Impacted the Nation”
No full textThis article is one of three responses to James E. Schultz’s reflections on how mathematics education in Ohio—particularly at The Ohio State University—has shaped mathematics teaching and learning across the United States and beyond. Schultz’s contributions are oral histories in written form, blending biographical and autobiographical elements. My response follows a similar approach. After a brief introduction, I reflect on—and expand upon—Schultz’s articles: Laying the Groundwork (2024a) and Incorporating Technology (2024b). I then examine how the issues and legacy discussed in these pieces relate to contemporary mathematics education and how Ohio continues to influence the field on a broader scale. I conclude with an epilogue recounting my first encounters with several key figures in this rich mathematical narrative
Doing Good to All People: Amish Relief and Development Ministries
No full textThe Old Order Amish church is experiencing a vibrant new chapter in its American experience as it gains agency in the areas of Christian relief and development ministries. Scholars have described the energetic and highly successful entrepreneurial spirit among the Amish over the past decades. This paper documents how the Amish are building on their success as sophisticated business leaders in creating Christian relief and development ministries. The Amish community has leveraged the lessons learned as entrepreneurs toward nonprofit ministries serving people well beyond their own Anabaptist communities. Three case studies—Gifts for Relief and White Horse Relief Center, Mennonite Disaster Service and Amish Storm Aid, and Plain Community Agricultural Exchange—serve as examples of the nascent Amish agency of doing good deeds for people beyond their own Anabaptist communities and of Amish conceptualizing and actualizing Christian relief and development ministries. These three ministries are only the beginning of what likely will be many more Amish-led relief and development ministries. The paper also notes that non-Amish relief and development ministries who seek to partner with the Amish will need to move from an often-paternalistic relationship to a peer-to-peer partnership with the Amish