College of Saint Benedict and Saint John's University
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Bayt Jadeed: Seeking Home
No full textBayt Jadeed: Seeking Home explores the parallels between Somali refugees\u27 experiences in St. Cloud, MN and refugees\u27 experiences in Germany. Through the commonalities in experiences, we hope to present a variety of perspectives to encourage a complex and honest conversation about how we define community
Means and Methods: Episode 1 with Dr. Emily Kuffner
No full textCSB/SJU Libraries Director Kathy Parker interviews Dr. Emily Kuffner, Visiting Assistant Professor of Hispanic Studies. Dr. Kuffner studies the Golden Age (16th and 17th century) of Spanish Literature, with a focus on women writers. Her most recent book is Fictions of Containment in the Spanish Female Picaresque: Prostitution and Architectural Space in the Early Modern Mediterranean (Amsterdam University Press, 2019)
CEP: The Community Education Project, aka The Farm : An Intentional Living Community for CSB/SJU Students, 1968-1970
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The Problem with White People, with Insight from St. Paul
Get PDF“I’m proud to be white,” someone recently told me. He interjected the comment in a contentious political conversation. I responded by advocating “more caution” in expression. The exchange fizzled without resolution. Yet this phrase, “proud to be white,” continues to disturb. My conversation partner was no white supremacist. But his chosen phrase would have fooled many. What lies within it is a key for understanding a threatening and intractable problem of American society: what I call “the problem of white people.
Negotiating with North Korea: The Challenges and Opportunities of Summit Diplomacy
No full textJenny Town is the Assistant Director of the US-Korea Institute at the Johns Hopkins School of Advanced International Studies (SAIS) and manages programs on North Korea, nuclear weapons, nuclear energy, and energy security in Northeast Asia. She is the Managing Editor and Producer of “38 North,” a web-journal providing analysis on events in and around the DPRK. She is also an expert reviewer for Freedom House’s Freedom in the World Index, where she previously worked on the Human Rights in North Korea project.
Prior to working in Korean affairs, she was the Communications Director for Peace X Peace; the Director of the Washington (DC) Office/Special Projects Manager for Government Relations at the College Board; and a Project Manager at Clarity Coverdale Fury Advertising, Inc. She holds a B.A. in East Asian Studies and International Relations from Westmar University and a Master of International Affairs from Columbia University’s School of International and Public Affairs. She is a Senior Fellow of the Melton Foundation and sits on the Board of Directors for Korean Focus
Spencer Reece: Poetry Reading and Audience Q&A
No full textSpencer Reece is an ordained Episcopalian priest, who currently works as a chaplain in Spain. His first poetry book, The Clerk’s Tale (2004), was chosen for the Bakeless Poetry Prize by Louise Glück and later adapted into a short film produced by James Franco. His poetry collection The Road to Emmaus (2013) was nominated for the National Book Award. Reece has received numerous fellowships, including from the Guggenheim Foundation, the National Endowment for the Arts, and the Library of Congress. Reece received a grant from the Fulbright Foundation to fund his work of teaching poetry in a Honduran orphanage in 2012-2013, and compiled and published a book of his students’ poems: Counting Time Like People Count Stars: Poems by the Girls of Little Roses, San Pedro Sula, Honduras (2017). Reece’s experiences with these students was also filmed and produced into a documentary: Voices Beyond the Wall: Twelve Love Poems from the Murder Capital of the World
Investigating the Therapeutic Potential of Targeting LRRC15 in Endometrial Cancer
Get PDFEndometrial cancer is the most common gynecological malignancy and accounts for 6% of all cancers in women. In 2018, there were an estimated 63,280 new cases of endometrial cancer resulting in 11,350 deaths. In advanced stages, aggressive forms of endometrial cancer are able to invade the peritoneum and metastasize to the omentum and bowel. Shridhar et al. have identified leucine rich repeat containing 15 (LRRC15), a protein involved in cell adhesion and interactions with the extracellular matrix (ECM), as a potential therapeutic target due to its significantly higher expression in ovarian cancer tumors that have metastasized to the omentum and bowel when compared to their matched primary tumor counterparts. Additionally, Shridharet al. have shown that LRRC15 is capable of associating directly with β1-integrin and promotes invasion and metastasis through the activation of focal adhesion kinase (FAK) in ovarian cancer. In this study, knockdown of LRRC15 in endometrial cancer cell lines lowered the expression of proteins within the FAK signaling pathway, decreased cancer cell adhesion, and decreased cell migration in vitro. Conversely, induced overexpression of LRRC15 led to an increase in expression of proteins in the FAK pathway and an increase in cell adhesion. Treatment of endometrial cancer cell lines with the therapeutic agent ABBV-085, a drug antibody conjugate which targets cells expressing LRRC15, was tested in vitro and demonstrated high specificity compared to the control with an IC50 between 0.1-1.0 nM. Overall, our results from LRRC15 knockdown and ABBV-085 treatment demonstrate that targeting LRRC15 may be therapeutically beneficial in endometrial cancer