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Don\u27t miss these new releases by the world\u27s leading chefs and culinary experts
別錯過以下由知名大廚和烹飪專家撰寫的新
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Get PDFSingapore fried Hokkien prawn noodles prepared by students of the International Culinary Institute
由國際廚藝學院學員精心烹調的新加坡福建炒蝦
Candida albicans Secreted Aspartic Protease 7 is Essential for Damage of Human Oral Epithelial Cells
Get PDFAims: Candida albicans is an important human fungal pathogen in clinical settings. It possesses a wide spectrum of virulence traits, including but not limited to the production of Secreted Aspartic Proteases (SAPs), to invade host cells under predisposing conditions. The aims of the present study were to investigate the functional role of C. albicans SAP7 in invasion ability. Methods: The present study was carried out to construct C. albicans sap7Δ/Δ mutant strain using a PCR-based gene disruption method. The behaviors of this SAP7 knockout strain was evaluated and compared with the wild type and SAP7 complemented strains between human oral epithelial cells with respect to endocytosis, invasion, and tissue damage. Results: Compared with the wild type C. albicans strain, a 52% reduction in the endocytosis of the sap7Δ/Δ mutant strain by oral epithelial cells was observed, as well as a 25% attenuation of internalization, and a 27% reduction of tissue damage (P\u3c0.05). Conclusion: Our data clearly demonstrates that C. albicans SAP7 contributes to tissue invasion into human oral epithelial cells which warrant further investigations as potential targets for antifungal interventions. Keywords: Candida albicans; Secrete
Contemporary practices of strength and conditioning coaches in professional cricket
No full textThis study describes the contemporary practices of strength and conditioning (S&C) coaches in male professional cricket. Thirty-three S&C coaches working with international and professional club teams across seven countries completed an online survey. The survey consisted of 45 questions (35 fixed responses and 10 open-ended), with eight sections: (a) background information, (b) muscular strength and power development, (c) speed development, (d) plyometrics, (e) flexibility development, (f) physical testing, (g) technology use, and (h) programing. Most S&C coaches were educated to degree level (97%) or higher, with 91% of degrees being in a sports science-related field. Furthermore, 73% held S&C and 40% cricket coaching certifications. Isometric type resistance training exercises (94%) were frequently programed by S&C coaches, with squats and deadlifts (including variations) deemed the most important strength development exercises. Ratings of perceived exertion (58%) was most used for determining set loads. Hang clean (64%) and multiple hops/lunges (85%) were the most prescribed Olympic weightlifting and plyometric exercises. Speed gates (85%) were the most used technology-based equipment. Open-ended questions revealed, 45% of S&C coaches believed time constraints, scheduling and fixtures are the main issues faced in their role. Position-specific demands (61%) was the predominant method used for individualizing players training strategies. The information presented in this study is valuable for those pursuing or currently working as an S&C coach in professional cricket to align, compare, and explain their practices. Furthermore, will provide insight for the wider athlete support team (e.g., sports coaches and physiotherapists) on the practices of S&C coaches
Off-training physical activity and training responses as determinants of sleep quality in young soccer players
Get PDFThis study aimed to quantify and assess the relationship of young soccer players\u27 off-training physical activity (PA) and training responses on sleep quality. Eleven adolescent soccer players (13 ± 0.5 years old) were monitored during weekdays for four consecutive weeks, throughout soccer practice days. Off-training PA and sleep quality were assessed using 100 Hz tri-axial accelerometers and training responses analyzed using 20 Hz global positioning measurement units. A cluster analysis classified all cases into three different dimensions, (1) off-training PA, (2) training responses and (3) sleep quality. For each dimension, the most important variables for classifying the cases into clusters were sedentary PA and moderate-to-vigorous PA; total distance covered and impacts; and sleep onset latency and sleep fragmentation index, respectively. Afterwards, a correspondence analysis was used to identify whether off-training PA and training responses affected sleep quality. Results exposed that high to medium off-training PA combined with medium to high training responses may have decreased sleep quality. Conversely, no correspondence was observed between off-training PA and training responses, with higher sleep quality. This study emphasizes the importance of sports organizations adopting a holistic approach to youth soccer players’ development, that appropriately considers the inter-relationship between lifestyle, performance and health-related information
Practices of strength and conditioning coaches in professional sports: a systematic review
Get PDFThe practices of strength and conditioning (S&C) coaches have been reported in various professional sports. This study aims to comprehensively assess this available evidence to help establish whether theoretical, practical, and evidence-based guidelines align with the practices employed by these experienced S&C coaches. Three databases were searched (PubMed, SPORTDiscus, and Cochrane) until November 2020. Studies surveying the practices of S&C coaches in professional sports using a survey design with common questions, written in English, and published in peer-reviewed journals were reviewed. Eight studies (n = 318 S&C coaches) were finally included. All studies adapted a similar survey, providing a strong basis for comparison between sports. Periodization strategies were widely used (89%), with training volume consistently reduced during the in-season period. Olympic weightlifting was commonly used across sports, except in baseball (29%). Plyometric exercises were predominantly prescribed for speed development (74%) and lower body power (68%), which were mostly programed as complex training (45%) and conducted all year round (52%). Flexibility exercises were mostly performed before practice (83%) for 6–10 min (40%). Physical tests were mainly conducted during the pre-season period (66%), with body composition (86%) being the most used test. S&C coaches generally adhered to current guidelines and research in S&C concerning training prescription and physical testing. Whereas, Intersport differences were also noted and further discussed. Results of this study can be used by S&C coaches to plan, implement, and review their professional practices. Furthermore, may inform the development of general and sport-specific guidelines, and future research in S&C
In-season training responses and perceived wellbeing and recovery status in professional soccer players
Get PDFThis study aimed to describe professional soccer players’ training responses during a competitive season and to investigate the relationship between these responses with wellbeing and recovery indices. Thirteen professional soccer players from the same Spanish Second Division team were monitored during a sixteen-week in-season period. Players’ external loads were analyzed using global positioning measurement units (GPS). Additionally, subjective reporting of sleep quality, sleep duration, fatigue, muscle soreness, and stress were assessed with a customized wellness questionnaire at the beginning of each training session. A two-step cluster analysis identified profiles of different training responses generally described as lower-demand sessions, intermediate-demand sessions, running-based sessions, and sprint-based sessions; which were discriminated by different total distance covered and high-intensity actions. Interestingly, no probabilistic interactions were found between these training responses with wellbeing and recovery markers (i.e., Bayes factor \u3c 1 suggesting no evidence, for all the variables). These findings may raise concerns about using self-reporting tools, as they show that players’ wellness data is probably not accounted for when coaching staff plan and optimize the training process. However, results should be interpreted with caution, due to representing a single team and coaching staff
Artist Interview - Zach Johnson
Get PDFZach Johnsen is a multi-disciplinary artist and designer, working both in the commercial sphere and fine-art world. He uses graphite, watercolour, pen and ink and acrylic on mostly 2D surfaces and by far his most trusted medium is the Micron pen. He uses them exhaustively to describe an ever-expanding world of ghouls, monsters and misfits — the shady characters in everyday life and how they expose themselves in our world. His work is frenetic and chaotic, an explosion of lines and colour influenced by infomercials, cartoons, sweets and the over-consumption of popular culture. Johnsen has lent his unique style of frenetic pen lines, jumbled character piles and explosive colour to a variety of applications. He has worked with Bulleit Bourbon, MTV, K2 Snowboards, ESPN, Nike, Gnu Snowboards, Icon Motosports, Slingshot Wakeboards and Sony/BMG. His fine-art work has been displayed across the US, in Australia, Denmark, Japan and the UK. He currently splits his time between northern New Hampshire and Portland, Oregon in the US