12691 research outputs found
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Alumni Portrait Unveiling, Hon. Alma Lopez, 2006
No full texthttps://commons.stmarytx.edu/portrait2006Lopez/1053/thumbnail.jp
Alumni Portrait Unveiling, Hon. Alma Lopez, 2006
No full texthttps://commons.stmarytx.edu/portrait2006Lopez/1067/thumbnail.jp
Alumni Portrait Unveiling, Hon. Alma Lopez, 2006
No full texthttps://commons.stmarytx.edu/portrait2006Lopez/1100/thumbnail.jp
Aspen Leading Edge Podcast, Episode 101: A Path Forward with Neil Handwerker and Kimberly Fin
No full textNeil Handwerker and Kimberly Fine, co-founders of Ex Judicata, will join Patty Roberts for a discussion about Ex Judicata and how it serves law students, law schools, lawyers, and law firms. From the wide range of webinars to the career match tool to access to multiple career coaches, this service is for anyone looking for a different career.https://commons.stmarytx.edu/edge/1070/thumbnail.jp
Lawtina Network Summit, St. Mary\u27s University School of Law, 2024
No full texthttps://commons.stmarytx.edu/lawtina2024/1011/thumbnail.jp
How are emojis interpreted by different generations
Get PDFEmojis have become a universal tool for expressing emotions, improving intelligibility, and expressing tone in text-based conversations as their use in digital communication has grown substantially. The purpose of this study is to investigate how emojis function in communication and how they affect the emotional tone and intelligibility of messages. In order to find out more, we will look at how various groups use emojis in different situations, such as formal versus informal communication. In order to present a thorough grasp of their impacts on communication dynamics, we will concentrate on quantitative elementshttps://commons.stmarytx.edu/rscpos25/1048/thumbnail.jp
The acute effects of high-intensity functional training on inhibitory control
No full textHigh-Intensity Functional Training (HIFT), such as CrossFit®, integrates high-intensity, multi-joint movements and has gained attention for its potential to enhance both physical and cognitive performance. While acute resistance exercise (RE) is known to influence physiological responses like heart rate variability (HRV) and cognitive functions such as inhibitory control, the specific effects of CrossFit®—a structured HIFT program—on cognitive outcomes remain underexplored, particularly when comparing trained CrossFit participants to untrained or non-CrossFit populations. HIFT’s unique combination of cardiorespiratory and muscular stress may uniquely enhance cognitive processing speed and response stability, especially in individuals with chronic CrossFit® experience. However, it is unclear how these effects differ between trained CrossFitters, who may adapt to HIFT’s demands, and non-CrossFitters, who lack such training exposure. This study aims to compare the acute effects of a single bout of CrossFit® exercise on cognitive function—specifically inhibitory control, processing speed, and response variability—between trained CrossFit participants (≥6 months experience) and a nonCrossFit population performing resistance exercise, providing insight into how training history modulates cognitive responses to high-intensity exercise.https://commons.stmarytx.edu/rscpos25/1028/thumbnail.jp
Storage batteries (Renewable energies/Cars) - Background for CURE Battery Discharge Project
Get PDFIn the past, and even today, Texas is known for its oil rigs and non-renewable energy sources, but it has also become a pillar for solar and wind turbine created power. As of late, the usage of these kinds of renewable resources has become essential to keep Texas as efficient as we once were in an ever growing world, where more people need more energy. However, a caveat concerning renewable energy resources is how available they are. At first, this unfamiliar territory led to people doubting its productivity when there was a lack of wind or sunshine. The solution to this: lithium ion batteries. These are considered “smart” batteries and have the ability to store energy for later use when these resources are not readily available.
Before the use of these lithium-ion batteries, renewable energy systems and resources would use things like compressed air, mechanical gravity storage, and flow batteries, to keep energy during no peak times.Initially, lithium-ion batteries and their storage abilities can be costly to set up and maintain. There is also concern for lithium, which is a metal that comes from earth , to continue to work long term. These resources can sometimes affect the environment negatively. However, this advancement in technology allows for efficiency and can take the burden off of non-renewable resources and, comparatively, affects the environment less than drilling. The battery is efficient because it is run by software. The utilization of these batteries reduces dependency on the grid during peak hours and can save customers significant amounts of money. The U.S. remains behind compared to other countries,, but Texas stays at the forefront.https://commons.stmarytx.edu/rscpos25/1027/thumbnail.jp
Key factors in U.S. mass shootings: A statistical approach
No full textMass shootings in the U.S. have surged at an alarming rate. From 1976 to 2018, there were 155 mass public shootings, resulting in 1,078 deaths and 1,694 nonfatal injuries and the rate has only accelerated in recent years. In just eight years (2013–2021), over 200 more occurred. Understanding the factors behind these tragedies is critical for prevention. The 2022 Uvalde school shooting, where an 18-year-old legally purchased assault rifles before killing 21 people, exemplifies the consequences of easy firearm access. By identifying patterns, we can help shape policies to reduce these horrific events and protect communitieshttps://commons.stmarytx.edu/rscpos25/1043/thumbnail.jp
Investigating the drug response of PDAC cells to Pan-KRAS inhibitor
No full textPancreatic ductal adenocarcinoma (PDAC) is an exocrine pancreatic cancer. It is one of the most lethal types of cancer and is projected to become the second leading cause of cancer-related deaths by 20401 . One major challenge in treating PDAC is drug resistance and the lack of effective treatments. Oncogenic KRAS mutation and loss of function mutation in tumor suppressor genes including P16, TP53, and SMAD4 are found in most PDAC patients. It is unclear whether the different driver mutations can affect the tumor responses to chemo- and targeted therapy. Gemcitabine, a chemotherapy drug, is a cytotoxic agent that has been used for treating pancreatic cancer2 . RMC7977, a most recently developed drug that targets active RAS proteins, shows strong tumor-specific effects in pre-clinical models of PDAC3 . Transcription factors are proteins that regulate gene expression, which may play a role in cancer drug resistance. We proposed to perform an overexpression screen using a commercially available cDNA library of transcription factors in our primary human pancreatic acinar organoids, aiming at identifying key transcription factors that contribute to drug resistance.
The research project aims to characterize the drug response from PDAC cells harboring different genetic mutation backgrounds. This will provide important guidance for precision medicine and pharmacotyping for individual PDAC patients to predict their drug response phenotypes and characteristics resulting from various genetic backgrounds.https://commons.stmarytx.edu/rscpos25/1031/thumbnail.jp