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Synthesis and Characterization of Ugi Adducts of Isatin
Full text linkB-lactam fragments have gathered attention in the chemistry field in being a pharmacophore for medicinal chemistry
- The Ugi reaction involves the reaction of an aldehyde, a primary amine, a carboxylic acid, and an isocyanide to generate α-acetoamido carboxamide derivates (Ugi adducts) -
We focused on the synthesis of the β-lactam derivatives: 1-Benzyl-N-(tert-butyl)-2-oxo-3(2-oxoazetidin-1- yl)indoline-3-carboxamide (4a), N-(tert-Butyl)-2-oxo-3-(2- oxoazetidine-1-yl) indoline-3-carbpxamide (4d) , and N- (tert-Butyl)-1-methyl-2-oxo-3-(2-oxoazetidine-1- yl)indoline-3-carboxamide (4e)
- The Ugi adducts of isatin were synthesized in TFE solvent by stirring the reactant mixture at room temperature and the conversion was monitored by TLC. The solvent was evaporated, and the crude product purified by flash chromatography.https://commons.stmarytx.edu/rscpos24/1040/thumbnail.jp
Synthesis and Characterization of Ugi Adducts of Isatin
Full text linkhttps://commons.stmarytx.edu/rscpos24/1043/thumbnail.jp
The Acute Effects of High-Intensity Functional Training on Inhibitory Control
Full text linkBased on findings from systematic reviews and metaanalyses, acute exercise (e.g., aerobic or resistance exercise) improves inhibitory control. However, a popular fitness trend, CrossFit®, has not been widely studied regarding its effect on inhibitory control. CrossFit® is a high-intensity functional training (HIFT) program that stresses the cardiorespiratory and muscular systems through complex, multi-joint movement patterns with minimal rests in-between sets. 1Wilke (2020) found that a 15-minute HIFT exercise bout improved working memory. However, the effect of HIFT on inhibitory control remains unclear. The purpose of the current study was to assess inhibitory control after a single bout of HIFT exercisehttps://commons.stmarytx.edu/rscpos24/1029/thumbnail.jp
Aspen Leading Edge Podcast, Episode 112: AI, Technology, and Contract Drafting with Monica Llorente
No full textMonica Llorente, Northwestern Law, discusses the third edition of Drafting Contracts: How and Why Lawyers Do What They Do and the updates she made since joining the author team. She also shares the importance of AI, how the topic is constantly changing, and what she is doing to ensure that all the content within the text related to the topic is relevant.https://commons.stmarytx.edu/edge/1081/thumbnail.jp
AI for learning: Lessons from the Classroom at St. Mary\u27s University
No full textTo what extent should college teachers guard against student use of AI? To what extent should we endorse and regulate the use of AI to enhance student learning? How can this be done? In this presentation, I share the results of a semester-long experiment in the use of AI for learning with students at St. Mary’s. Participants were registered for two distinct sections of a course in theology. Students in the control section were instructed not to use AI without explicit permission. Students in the experimental section were trained in AI prompting, required to use AI to work toward their learning goals, and asked to report on their interactions with the machine. The results point to several key distinctions that ought to inform AI classroom policy, including product-oriented v. process-oriented use of AI and plagiarism v. self-replacement. Survey data also point to existing AI habits and priorities among students with significant pedagogical implications.https://commons.stmarytx.edu/rsc25pres/1018/thumbnail.jp
St. Mary\u27s School of Law Graduation, 2018
No full texthttps://commons.stmarytx.edu/grad2018/1010/thumbnail.jp
St. Mary\u27s School of Law Graduation, 2018
No full texthttps://commons.stmarytx.edu/grad2018/1022/thumbnail.jp
St. Mary\u27s School of Law Graduation, 2018
No full texthttps://commons.stmarytx.edu/grad2018/1025/thumbnail.jp
St. Mary\u27s School of Law Graduation, 2018
No full texthttps://commons.stmarytx.edu/grad2018/1041/thumbnail.jp