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Borderline Personality Disorder and Interpersonal Theory of Suicide: Examining the Mediating Influence of Resilience and Social Support and Potential Moderators among Women Veterans
No full textBackground: Women veterans, the fastest-growing demographic within the U.S. veteran population, are projected to make up nearly 18% of all living veterans by 2040. Despite their growing numbers, they remain underrepresented in research, especially regarding mental health. Women veterans face increased suicide risk due to higher rates of trauma, depression, posttraumatic stress disorder (PTSD), and borderline personality disorder (BPD). According to Thomas Joiner’s Interpersonal Theory of Suicide, feelings of perceived burdensomeness (PB) and thwarted belongingness (TB) significantly contribute to suicide risk. This study examines the relationship between BPD severity, PB, and TB, considering mediators (resilience, social support) and moderators (depression, PTSD). Purpose: This study aimed to: (1) explore how depression, PTSD, resilience, and social support affect the relationship between BPD severity and PB/TB; (2) test whether resilience or social support mediates these relationships; and (3) examine how depression or PTSD moderated these effects. The study also explored group differences to better understand suicide risk in women veterans. Methods: Women veterans in a specialty inpatient program completed self-report measures assessing interpersonal needs, PTSD, suicide capability, depression, resilience, social support, and BPD symptoms within 24-48 hours of admission. Data were analyzed using mediation and moderation techniques. Results: The study included 204 women veterans (mean age = 41.75, SD = 10.63). The model examined associations between BPD symptoms and perceived burdensomeness (PB) and thwarted belongingness (TB), with resilience and social support as mediators and depressive and PTSD symptoms as moderators. BPD and depressive symptoms significantly predicted lower social support, while depressive symptoms also predicted lower resilience. In turn, greater social support and resilience were linked to lower PB; only social support significantly predicted TB. BPD symptoms indirectly influenced PB and TB through social support, but not through resilience. Depressive symptoms predicted higher PB and trended toward lower TB, while PTSD symptoms and interaction effects were nonsignificant. Conclusion: The findings support Joiner’s Interpersonal Theory of Suicide, showing that greater BPD symptom severity is associated with stronger perceptions of PB and TB, key suicide risk factors. Social support mediated the relationship between BPD and PB, while resilience negatively predicted both PB and TB. These results underscore the importance of targeting interventions that increase social support and resilience to reduce suicide risk among women veterans with BPD. Further research is needed to explore these mechanisms and develop tailored interventions for this population
The Interplay of Disability, Depression, Social Support, and Quality of Life in Middle-Aged and Young Couples Affected by Stroke: A Dyadic Path Analysis Using the Actor–Partner Interdependence Mediation Model
No full text<b>Objective:</b> The purpose of this study was to explore the impact of disability on dyadic quality of life (QoL) among stroke survivors and to examine the mediating role of social support in this process. <b>Methods:</b> Outcome measures were collected at four time points: baseline, 1 month, 3 months, and 6 months post-discharge. The Actor&ndash;Partner Interdependence Mediation Model was used to analyze the dyadic data. <b>Results:</b> A significant association was observed between a higher degree of disability and more severe depressive symptoms in stroke survivors (<i>&beta;</i> = 0.626) and their spouses (<i>&beta;</i> = 0.426). Survivors&rsquo; disability had a negative impact on their own physical health (<i>&beta;</i> = &minus;3.731) and indirectly affected the physical health of the spouse caregiver through the spouse caregiver&rsquo;s depression (<i>&beta;</i> = &minus;0.198). In addition, disability affects the survivor&rsquo;s own mental health through depression and social support (<i>&beta;</i> = &minus;0.231) and indirectly through the spouse caregiver&rsquo;s depression and their own social support (<i>&beta;</i> = &minus;0.156). <b>Conclusions:</b> Survivor disability has a major impact on depression and QoL in couples with stroke. It is recommended that healthcare providers should identify disability early in stroke survivors and then target interventions to improve the QoL of couples affected by stroke who are at high risk of negative emotions
Artificial Intelligence for Risk&ndash;Benefit Assessment in Hepatopancreatobiliary Oncologic Surgery: A Systematic Review of Current Applications and Future Directions on Behalf of TROGSS&mdash;The Robotic Global Surgical Society
No full text<b>Background:</b> Hepatopancreatobiliary (HPB) surgery is among the most complex domains in oncologic care, where decisions entail significant risk&ndash;benefit considerations. Artificial intelligence (AI) has emerged as a promising tool for improving individualized decision-making through enhanced risk stratification, complication prediction, and survival modeling. However, its role in HPB oncologic surgery has not been comprehensively assessed. <b>Methods:</b> This systematic review was conducted in accordance with PRISMA guidelines and registered with PROSPERO ID: CRD420251114173. A comprehensive search across six databases was performed through 30 May 2025. Eligible studies evaluated AI applications in risk&ndash;benefit assessment in HPB cancer surgery. Inclusion criteria encompassed peer-reviewed, English-language studies involving human s ubjects. Two independent reviewers conducted study selection, data extraction, and quality appraisal. <b>Results:</b> Thirteen studies published between 2020 and 2024 met the inclusion criteria. Most studies employed retrospective designs with sample sizes ranging from small institutional cohorts to large national databases. AI models were developed for cancer risk prediction (n = 9), postoperative complication modeling (n = 4), and survival prediction (n = 3). Common algorithms included Random Forest, XGBoost, Decision Trees, Artificial Neural Networks, and Transformer-based models. While internal performance metrics were generally favorable, external validation was reported in only five studies, and calibration metrics were often lacking. Integration into clinical workflows was described in just two studies. No study addressed cost-effectiveness or patient perspectives. Overall risk of bias was moderate to high, primarily due to retrospective designs and incomplete reporting. <b>Conclusions:</b> AI demonstrates early promise in augmenting risk&ndash;benefit assessment for HPB oncologic surgery, particularly in predictive modeling. However, its clinical utility remains limited by methodological weaknesses and a lack of real-world integration. Future research should focus on prospective, multicenter validation, standardized reporting, clinical implementation, cost-effectiveness analysis, and the incorporation of patient-centered outcomes
Streamlining Music Monographic Series Workflows at UH Libraries
No full textThe authors will provide an overview of University of Houston Libraries’ multi-year effort to ensure continued access and enhanced retrieval of their Music Library’s Historical Editions of Music (M2s) and Collected Works of Individual Composers (M3s). In July 2021, UH Libraries migrated their catalog from III Sierra to Ex Libris Alma. Post-Alma implementation outcomes resulted in the need to update various policies and procedures for receiving, cataloging, and processing M2s and M3s. The authors will discuss various workflows to streamline work, as well as data remediation work to enhance the discoverability of these indispensable music resources for researchers. Additional topics include developing collaboration strategies, intradepartmental workflow management, automation in libraries, and data remediation.Librarie
The Development and Validation of the Student-Athlete Resource Inventory
No full textCollegiate student-athletes face a distinct set of pressures as they balance rigorous athletic demands, academic expectations, and personal development. These pressures can influence their perceptions of available resources, such as mental health care, social support, and financial stability, which play a critical role in shaping well-being and life satisfaction. While resource availability has been broadly studied, existing tools fail to account for the perceived and context-specific nature of resources within the student-athlete population. Furthermore, little is known about how resource perceptions influence developmental trajectories or differ across key subgroups. The present study aimed to address this gap by developing and validating the Student-Athlete Resource Inventory (SARI), a multidimensional scale that captures student-athletes’ perceptions of the resources they rely on to navigate their experience. Using a multi-phase methodology, this study employed exploratory and confirmatory factor analyses, reliability testing, and regression modeling to assess the structure and function of the SARI. Results revealed five distinct resource domains: Social Support, Mental Resources, Financial Resources, Instrumental Responsibility and Emotional Resources with varying influence on life satisfaction. Additional group comparisons identified disparities in perceived resources across gender, race, sport type, and academic year
Linked Lives: The Importance of Considering Vicariously Experienced Discrimination for Youth and Parent Mental and Physical Health
No full textThe health of minoritized youth and their families is deeply intertwined with each other's social experiences: individual exposure to discrimination can spill over to family interactions, influencing everyone's health; families collectively experience racial ethnic segregation or marginalization within their communities; and at the same time; they also co-create experiences that foster cultural strengths and resilience. However, family members are often studied separately, and we currently know little about the ripple effects of discrimination across family systems and the corresponding individual health implications. I will present my research with nationally representative data demonstrating that family members are psychologically and physically affected by each other's experiences of discrimination. In addition, I also explore mechanisms of coping between parents and adolescents that may reduce the risk of experiencing psychological or physical distress from vicariously experienced discrimination. I will present preliminary findings from an ongoing data collection in Houston to understand how Black and African American adolescents and their parents communicate about and cope with discrimination together. The discussion will focus on understanding discrimination as a stressor that ripples across family systems and will end with therapeutic and practical recommendations to reduce the health burden of vicariously experienced discrimination for children and their parents
Job Satisfaction, Health Insurance Benefits, and On-the-Clock Health Insurance Administrative Tasks/Burdens: A Moderated Mediation Model
No full textThis study examines how individuals&rsquo; perceptions of the importance of their health insurance benefits (Insurance Importance) influence their overall job satisfaction (Job Satisfaction), with health insurance satisfaction (Insurance Satisfaction) serving as a mediator and time spent on insurance administrative tasks or burdens (Time Spent) acting as a moderator. Using survey data from a final analytic sample of 296 participants in the United States, we found that Insurance Satisfaction mediates the relationship between perceived Insurance Importance and Job Satisfaction. Moreover, the positive association between Insurance Importance and Insurance Satisfaction weakens when individuals spend more time managing insurance administrative burdens. Our findings highlight the critical need for organizations to strategically prioritize employee benefits, with a particular emphasis on streamlining and enhancing the efficiency of health insurance administrative process to reduce administrative burdens. By implementing such strategies, organizations can improve employees&rsquo; satisfaction with health insurance, thereby boosting their job satisfaction
Settlementality: Public Perceptions of Legal Settlement
No full textWhile popular depictions of civil lawsuits tend to focus on courtroom dramatics, the truth is that most cases never go to trial. Instead, they are resolved through private settlement agreements. The details of these settlements are often kept secret, leaving observers to draw their own conclusions about the underlying controversies. This talk explores the inferences that members of the public make when cases settle. I discuss several large-scale surveys and experiments, including over 2000 participants, suggesting that while people seem to generally understand the nature of legal settlements and appreciate the benefits that settlement agreements offer to the parties involved, they nonetheless tend to view settlements as admissions of responsibility or expressions of guilt. I also discuss several high-profile settlement agreements in comparison to my survey data
Navigating the UH Libraries Catalog and UH Digital Collections
No full textThis 1-hour session will discuss how to navigate various UH Libraries discovery platforms, including the library catalog and UH Digital Collections. The presenters will spend the first half of the session providing an overview of UH Libraries discovery platforms and demoing features. The second half will consist of a Q&A session with attendees to further explore what resources UH Libraries stewards and provides access to.Librarie
Investigating SUMOylation's Regulation of Non-coding RNA to Direct Maternal-Infant Health
No full textThe epigenetic link between maternal and infant health is critical. This is particularly true when considering infants with intestinal inflammatory diseases such as necrotizing enterocolitis (NEC). Infants with intestinal inflammatory issues, as in the case of NEC, are typically underdeveloped and underweight due to premature birth. These diseases are extremely critical due to the high mortality rate following diagnosis. Human milk has been shown to attenuate the progression of inflammation in the infant gut. The clinical benefit of human milk has been described; however, the biochemical mechanism for this positive clinical outcome remains unknown. In our research, we have identified a novel mechanism for packaging microRNA (miRNA) from mammary epithelial cells into exosomes transported through human milk. These exosomes are derived from mammary epithelial cells (MECs), and we link posttranslational modification of SUMO, small ubiquitin-like modifier, to directly influencing the specific miRNA packaged into exosomes. We further establish these human milk-derived exosomes regulate the transcriptome of the recipient, and we show this in a physiologically relevant human infant intestinal enteroid model. We show these human milk-derived exosomes exhibit protective effects to further membrane disruption in human infant enteroids. While breastfeeding supports the nutrition and development of the infant, the physiological changes that occur during lactation may have adverse effects in maternal health. Breast cancer continues to be a detriment to women’s health, and the period following birth is now considered a point of susceptibility for breast cancer incidence. Here, we investigate the role of SUMOylated proteins and their interactions with nucleic acids in breast cancer. We have shown that in endocrine therapy resistant breast cancer, the SUMO-modified form of androgen receptor (AR) highly associates with lncRNA at the chromatin. Furthermore, we have delineated a novel mechanism for lncRNA clearance at the telomeres and identified a potential biomarker for therapy response in breast cancer patients