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Lifestyle Changes and Medication vs. Medication Alone: Symptom Control of Parkinson Disease
Get PDFParkinson disease is multifactorial and predominantly effects the geriatric population. The mainstay of treatment for patients diagnosed is currently symptomatic treatment with dopamine replacement. The goal of this literature review is to identify possible lifestyle modifications that can delay progression of the disease or help prolong OFF time of symptoms. Lifestyle modification predominantly considered during this review included diet and physical activity. Included in the study were MIND, Mediterranean, and DASH diets. Considering the role of medication in this disease levodopa, dopamine agonists, monoamine oxidase B inhibitors and the addition of ropinirole to levodopa and their efficacy in treating parkinsonian symptoms was investigated. A literature review was conducted using electronic search database including, PubMed, Clinical Key and DynaMed. After thorough review of 12 articles regarding management of Parkinson disease with various modifications along with medications it was found lifestyle modifications are not significant in the management of Parkinson disease alone. However, there is evidence to support the benefits lifestyle modifications can have, including diet and physical activity, for those diagnosed with Parkinson disease. The addition of these changes have shown the possibility of reducing the OFF time in the disease as well as reducing the daily medication regimen needed.https://commons.und.edu/pas-grad-posters/1295/thumbnail.jp
The Efficacy of Probiotic Use in Patients with Anxiety and Depression
Get PDFGiven the impact of mental health disorders such as anxiety and depression, it is helpful to know the available resources and treatment options to offer patients to aid in the modulation of symptoms. The gut-brain connection has become more widely researched for its impacts on anxiety and depression. This bodes the question that if the gut microbiome can be altered, would there be a decrease in symptoms of anxiety and depression as a result? One way to alter gut microbiome is to implement a probiotic. To determine if this is an effective treatment option for anxiety and depression, a literature review was conducted using primarily randomized clinical trials. PubMed was the primary database that was used for this research. Articles were sorted and chosen based upon applicability to the problem being investigated, clinical trials, and a recent time frame of five years. Most of the articles reviewed found statistically significant differences in improvements of symptoms of anxiety and depression in the intervention group participants. Therefore, the results of this literature review suggest that implementing a probiotic either as sole therapy or adjuvant therapy can improve symptoms and severity of anxiety and depression. Probiotics are easily accessible as over-the-counter supplements. This provides an alternative treatment option or adjuvant option to anti-depressants that are frequently available to patients
Comparison of Cryopreservation of Ovarian Tissue Versus Cryopreservation of Oocytes in Fertility Preservation
Get PDFThis literature review aims to compare ovarian tissue cryopreservation (OTC) and oocyte cryopreservation as methods for fertility preservation. Electronic health science databases including PubMed, Clinical Key, ScienceDirect, and UpToDate were utilized. Seven articles met the inclusion criteria and were analyzed for this comprehensive review. This review indicates that both oocyte and ovarian tissue cryopreservation can effectively preserve fertility, however, ovarian tissue cryopreservation is deemed most effective for prepubertal girls at high risk of iatrogenic primary ovarian insufficiency (POI), or women who are unable to postpone gonadotoxic treatment. Ovarian tissue cryopreservation offers advantages that oocyte cryopreservation does not, such as multiple spontaneous pregnancies from a single transplant and resumption of ovarian function. Ovarian tissue cryopreservation also does not carry the risks associated with ovarian stimulation and delaying gonadotoxic treatment, unlike oocyte cryopreservation. Despite successful birth rates and low surgical risks associated with ovarian tissue cryopreservation, studies reveal a low utilization rate, with women often considering stored ovarian tissue as a “backup plan”. There is a need for further additional research on ovarian tissue cryopreservation, especially in the younger age groups, as there was limited participation in follow-up studies. Overall, the studies analyzed in this literature review support ovarian tissue cryopreservation as an effective method of fertility preservation but emphasize the importance of further investigation and follow-up studies
Patient Outcomes With Tele-Emergency Medicine Services in Rural Areas
Get PDFThe purpose of this literature review was to examine patient outcomes with the use of teleemergency medicine. Tele-emergency medicine serves as a tool to expand the healthcare team in rural facilities by connecting them with specialized providers, typically via video conference call, for assistance in surge or low-staff situations, or for guidance in more complicated cases that rural providers might typically transfer to a larger hospital. A benefit of adopting a teleemergency medicine service is that it can shorten time to care and reduce the need for transfers, thereby reducing associated costs. The question arises as to whether patient outcomes are improved as well, or if the limitations of telemedicine lead to lower quality of care. For this review, databases such as PubMed and Embase were used to compile current research on the topic. The results of this study suggest that the quality of patient care improves with the use of tele-emergency medicine. This is demonstrated by measures such as a decrease in medical errors and positive reviews from medical staff. Discharge status appeared to be affected by using teleemergency medicine, resulting in increased admissions, decreased discharges, and decreased transfers
Mood Stabilizers vs Stimulants for the Management of Attention-Deficit/Hyperactivity Disorder and Comorbidity Bipolar Disorder
Get PDFBD and ADHD share a lot of similar symptoms such as comorbidities, age of onset, chronic, enduring course of illness with interference of vocational, educational, and developmental milestones. There is immense challenge when it comes to differentiating these disorders due to significant overlap and variable courses of psychopathology in children. Providers need to be aware of the medications that are beneficial for each condition separately and which medications can benefit both conditions. Mood stabilizers are commonly used in bipolar disorder while stimulants are a common treatment for ADHD. A literature review was performed using search databases such as PubMed to answer the question of whether mood stabilizers, stimulants, or the combination of the two would have the most positive effect on these two disorders in children. A total of 14 articles fit the criteria for this literature review. The diversity of pharmacological interventions, including mood stabilizers like lithium and divalproex sodium, and atypical antipsychotics such as aripiprazole and risperidone, underscores the complexity of managing this population. The reviewed literature suggests that stimulant medications, such as lisdexamfetamine dimesylate and mixed amphetamine salts, may contribute to an improved quality of life for individuals with comorbid ADHD and BD. This literature review determined that children with BD and comorbid ADHD respond well and show improvement in ADHD symptoms when treated with polypharmacy of a mood stabilizer and a stimulant, with the suggestion that the mood stabilizer be started first before adding the stimulant.https://commons.und.edu/pas-grad-posters/1321/thumbnail.jp
Interrogating a ChatGPT-generated Literary Analysis
Get PDFFor this assignment, students will work in groups to read through and critique a literary analysis generated by ChatGPT
