Indonesian Journal of Obstetrics and Gynecology (INAJOG)
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Pentoxifylline as a Therapy for Thin Endometrial Lining in Infertility
Get PDFObjective: To evaluate the effect of pentoxifylline as a single regimen
therapy for thin endometrial lining in infertility.
Method: A cross-sectional retrospective research was held in Yasmin
Clinic - Kencana, Dr. Cipto Mangunkusumo Hospital from 2010 until
2011. Our respondents were women with infertility problem.
Result: There was significant improvement of endometrial lining in
respondents who received pentoxifylline in the first month
(
Treatment Response of PlatinumBased Chemoradiation on Locally Advanced Cervical Cancer
Get PDFObjective: To evaluate the efficacy (treatment response), toxicity,
and overall survival of concomitant chemoradiation (CRT) with
three-weekly cisplatin-ifosfamide compared to CRT with weekly cisplatin
in advanced stage cervical cancers (stage IIB-IIIB).
Method: This is a historical cohort between 32 patients receiving
CRT with three-weekly cisplatin and ifosfamide and 29 patients receiving
weekly cisplatin in Gynecologic Oncology division outpatient
clinic and ward, Dr. Cipto Mangunkusumo Hospital.
Results: There was no significant difference in treatment response,
overall and disease-free survival. There was more gastrointestinal
toxicity in the cisplatin-ifosfamide arm compared to the other arm
(p=0.014), but other toxicity effects were not different.
Conclusion: Platinum based-chemoradiation has the same efficacy
in terms of treatment response for locally advanced cervical cancer.
[Indones J Obstet Gynecol 2015; 3-4: 212-221]
Keywords: cisplatin, concomitant chemoradiation, ifosfamide, locally
advance stage cervical cance
Serum Vascular Endothelial Growth Factor (VEGF) in DMPA Acceptors: Influence on Bleeding Occurrence
Get PDFObjective: To analyze the relationship between levels of serum vascular
endothelial growth factor (VEGF) and bleeding occurrence in
depo medroxyprogesterone acetate (DMPA) acceptors.
Method: We employed a crossâ€sectional study on 70 DMPA acceptors
with DMPA use of 3 to 6 months who presented for midwifery
service in Palembang. Blood samples were obtained in order
to assess levels of serum VEGF using ELISA (enzymeâ€linked immunoabsorbent
assay) method. Laboratory assessments were carried
out in PRODIA laboratory in Jakarta.
Result: We recruited 70 subjects into our study. After 3 to 6 months
of using DMPA, as much as 26 subjects (37.1%) reported complaints
of bleeding and 44 subjects (62.9%) reported no bleeding. The mean
level of serum VEGF in DMPA acceptors with bleeding was 355 K
170 pg/ml, and 323 K 202 pg/ml in acceptors with no bleeding. We
identified a significant association between duration of use and
bleeding occurrence (p0.05).
Conclusion: In our sample, we found an association between duration
of DMPA use and presence of bleeding but VEGF levels was not
found to be different in women experiencing abnormal uterine
bleeding and those who did not.
Keywords: bleeding, DMPA acceptor, serum VEG
Complete Atrioventricular Block in Pregnancy
Get PDFObjective: Complete heart block is an extremely rare and serious
complication in pregnancy. Pregnancy outcome in patients with
atrioventricular conduction block are unknown, with only a limited
number of case reports published. This paper is aimed to report our
case and review the available background literature.
Method: Case report.
Case: A twentyâ€nine years old primigravida in labor presented at 38
weeks of gestation with referral from the primary health center due
to bradycardia and her previous history of cardiac problem. Patient
has been diagnosed with total atrioventricular block since 2 years
ago. Electrocardiography assessment showed the presence of complete
heart block. She was then planned for an emergency Caesarean
section and later a temporary transvenous pacemaker was implanted.
Conclusion: Management of complete atrioventricular block in
pregnancy requires a good team consisting of obstetrician, anesthesiologist
and cardiologist.
Keywords: atrioventricular, bradycardia, heart block, pacemaker,
pregnanc
Survival and Side Effects of Cisplatin/Cyclophosphamide and Carboplatin/Paclitaxel Adjuvant Chemotherapy in Stage IC-IV Ovarian Cancer
Get PDFObjective: To compare the survival and side effects in epithelial
ovarian cancer patients receiving adjuvant chemotherapy of cisplatin/
cyclophosphamide and carboplatin/paclitaxel.
Method: We recruited epithelial ovarian cancer patients receiving
cisplatin/cyclophosphamide (group A) or carboplatin/paclitaxel
(group B) adjuvant chemotherapy after surgery. Chemotherapy was
given for six cycles. Overall survival and side effects were assessed.
Result: A total of 49 patients were recruited, consisting of 25 patients
for group A and 24 patients for group B. In this study, the overall
survival of stage IC-IV ovarian cancer patients was 37.3 months in
group A (95%CI=31.86-43.46) and 35.5 months (95%CI= 13.93-
43.46) in group B (
Husband’s Support is a Main Factor Associated with Contraceptive Practices
Get PDFObjective: To determine factors associated with contraceptive practices
in Palabuhanratu, West Java.
Method: We conducted a cross-sectional study at the Obstetrics and
Gynecologic ward of Local General Hospital of Palabuhanratu District,
between March and June 2012. Data was collected using directed
interview method by investigators and midwives, using non-validated
questionnaires. Statistical analysis was performed using SPSS 20.0,
utilizing Chi-Square test for nominal data and Kruskal-Wallis test for
numerical data.
Result: We obtained 71 samples. The only factors which are significant
were age group of 20-35 years old (OR=3.5, 95%CI=1.1-11.1,
p=0.025) and husband’s support (OR=14.67, 95%CI=1.52-141.18,
p=0.012). The most recognized contraceptive methods familiar to
our respondents were injection (94.4%) and pills (93.0%), and the
most useful source of information on contraception was medical personnel
(73.2%).
Conclusion: Husband’s support is a main factor associated with contraceptive
practice. The choice of contraceptive method should be adjusted
according to the ability and desire of patients to prevent failures
in family planning.
Keywords: associated factors, contraception, husband’s suppor
Female Sexual Function at Three Months Post-delivery in Spontaneous Labor and Cesarean Section
Get PDFObjective: To study the comparison of encouragement, stimuli, orgasm,
pain and satisfaction of female sexual function at 3 months
postpartum between spontaneous delivery and cesarean section in Dr.
Cipto Mangunkusumo Hospital in Jakarta.
Method: This was an observational research, sexual function was
measured at three months post-delivery with Female Sexual Function
Index (FSFI) questionnaire. The study design used was cross sectional
with consecutive sampling. Analysis for comparative nonpaired
categorical variables was done using Chi square or Fisher analysis.
Analysis for confounding variables was carried out using multivariate
logistic regression.
Result: From 150 respondents, 43.3% had sexual dysfunction, with
52% of the spontaneous labor group and 34% of the cesarean section
group. Bivariate analysis showed that occurrence of sexual dysfunction
at three months post-spontaneous labor was 1.5 times higher
(95% CI 1.02-3.19) compared with cesarean section. Sexual encouragement
shows a two-fold difference (95% CI 1.17-3.40) compared
to cesarean section. However, orgasm disturbance was 8 times higher
(95% CI 1.90-3.58) in the spontaneous labor group, with confounding
variable of perineal rupture. Disturbance of sexual stimuli, satisfaction,
and pain were not significantly different between spontaneous
labor and cesarean section. Multivariate analysis found that spontaneous
labor was statistically significant for sexual dysfunction at
three months post-delivery in patients with sexual encouragement
(RR=2.716, p=0.008) and orgasm accession dysfunction (RR=
6.952, p=0.031). However, the more than 30 years old of age variable
was statistically significant in sexual dysfunction variable with RR=
2.60 and p=0.021.
Conclusion: Spontaneous labor is statistically significant for sexual
dysfunction at three months post-delivery, especially for sexual encouragement
and orgasm accession. Meanwhile, the variables with the
age of 30 years old or older of age were influential on sexual dysfunction,
especially to the sexual stimuli variable.
Keywords: labor method, sexual dysfunction, three months postdeliver
C-Telopeptide in Relation with Osteoporosis Risk Classification Using Osteoporosis Self Assessment Tools for Asian (OSTA) in Postmenopausal Women
Get PDFObjective: To determine the correlation between Câ€telopeptide with
osteoporosis risk by using Osteoporosis Self Assessment Tools for
Asian (OSTA) in postmenopausal women.
Method: An analytic crossâ€sectional study of 31 postmenopausal
women in Prof. Dr. RD Kandou Hospital, Manado. Samples were collected
through consecutive sampling. Data was analyzed using Pearson
test with significance level of p>0.05.
Result: Our sample consisted of 31 postmenopausal women. Mean
OSTA score is â€1.02K2.54. Sixteen women (51.61%) were deemed to
have low risk, 8 women (25.81%) deemed to have moderate risk
and 7 women (22.58%) deemed high risk based on the OSTA score.
The mean Câ€telopeptide plasma level of our sample is 0.52K0.25
ô€g/l. We found plasma Câ€telopeptide level and OSTA score were normally
distributed. Correlation analysis using Pearson test identified
a significant negative correlation between plasma Câ€telopeptide level
and OSTA score (r=â€0.768; p=0.001).
Conclusion: There is a significant negative correlation between
plasma Câ€telopeptide level with risk of osteoporosis based on OSTA
score in postmenopausal women.
Keywords: OSTA score, plasma Câ€telopeptide, postmenopausal wome
Postoperative Urinary Retention in Total Vaginal and Abdominal Hysterectomy in Benign Gynecological Disorders
Get PDFObjective: To assess and compare the incidence of urinary retention
in patients postâ€vaginal and abdominal total hysterectomy for benign
gynecological disorders.
Method: This is a comparative analytical study with prospective and
retrospective cohort design, which was conducted in Dr. Cipto Mangunkusumo
Hospital and Persahabatan Hospital from June 2012 to
February 2014.
Result: We recruited thirtyâ€eight research subjects who underwent
abdominal hysterectomy, and 18 subjects who underwent vaginal
hysterectomy. The majority of cases underwent the procedure for
abnormal uterine myoma (55.5%) and adenomyosis (28.9%). Incidence
of urinary retention postâ€hysterectomy was 33.3% for vaginal
hysterectomy, and 31.6% for abdominal hysterectomy. The comparison
of the incidence of urinary retention showed no difference
between vaginal and abdominal hysterectomies (RR=1.056).
Conclusion: Vaginal hysterectomy does not increase the incidence
of postoperative urinary retention. However, this study suggests the
need for further research with a larger sample size, employing prospective
cohort design, with preoperative measurement of postvoiding
urine volume (PVR).
Keywords: abdominal hysterectomy, urinary retention, vaginal hysterectom