Indonesian Journal of Obstetrics and Gynecology (INAJOG)
Not a member yet
904 research outputs found
Sort by
Maternal Deaths due to Obstetric Hemorrhage in Padang, Indonesia: A Case-Control Study: Kematian Maternal Akibat Perdarahan Obstetri di Kota Padang: Sebuah Studi Kasus-Kontrol
No full textAbstract
Objective: To analyse the association between determinants of maternal deaths and obstetric haemorrhage in Padang, Indonesia.Methods: A retrospective case-control study was conducted in Padang, Indonesia from 2015 to 2019. Maternal deaths that occurred due to obstetric hemorrhage in Padang Health Department was compared to three mothers who survived from obstetric hemorrhage (controls) in Dr. M. Djamil General Hospital, Padang, Indonesia.Results: There were 20 deaths caused by obstetric hemorrhage during 2015 to 2019. Death records could only be found in 16 cases. The most common etiology of obstetric hemorrhage was uterine atony (62.5%). Determinants associated with maternal deaths due to obstetric hemorrhage were interval between pregnancies (p=0.045; OR:10.846), history of previous labour (p=0.003; OR:8.556), and antenatal care (p=0.003; OR:21.364). Age, parity, birth attendant, and mother’s educational level were not significantly associated with maternal deaths due to obstetric hemorrhage.Conclusion: Uterine atony was the most frequent etiology of maternal deaths due to obstetric hemorrhage. There was a significant association between pregnancy intervals, history of previous labour, and antenatal care with maternal deaths due to obstetric hemorrhage.Keywords: determinant, obstetric hemorrhage, maternal death.
Abstrak
Tujuan: Menganalisis hubungan determinan kematian maternal akibat perdarahan obstetri di Kota Padang.Metode: Sebuah studi retrospektif case-control dilakukan di Kota Padang dari tahun 2015–2019. Setiap kasus kematian ibu akibat perdarahan obstetri dari tahun 2015–2019 yang dilaporkan oleh Dinas Kesehatan Kota Padang dibandingkan dengan tiga kasus perdarahan obstetri yang tidak berakibat kematian di RSUP Dr. M. Djamil Padang. Analisis data menggunakan uji Chi-square.Hasil: Ada 20 kasus kematian akibat perdarahan obstetri selama tahun 2015–2019. Catatan kematian hanya dapat diperoleh pada 16 kasus. Etiologi terbanyak kematian akibat perdarahan obstetri ialah atonia uteri. Determinan yang berhubungan dengan kematian akibat perdarahan obstetri ialah jarak kehamilan (p=0.045; OR:10.846), riwayat persalinan sebelumnya (p=0.003; OR:8.556), dan antenatal care (p=0.003; OR:21.364). Tidak terdapat hubungan yang signifikan antara usia, paritas, penolong persalinan, dan tingkat pendidikan ibu dengan kematian maternal akibat perdarahan obstetri.Kesimpulan: Atonia uteri merupakan etiologi tertinggi kematian maternal akibat perdarahan obstetri. Ada hubungan yang signifikan antara jarak kehamilan, riwayat persalinan sebelumnya, dan antenatal care dengan kematian maternal akibat perdarahan obstetri.Kata kunci: determinan, kematian maternal, perdarahan obstetri
The Role of Thrombocytosis as a Prognostic Factor for Epithelial Ovarian Cancer: Peran Trombositosis sebagai Faktor Prognostik pada Kanker Ovarium Jenis Epitelial
Get PDFObjective: To determine whether thrombocytosis is a prognostic factor for epithelial ovarian cancer and its relationship with 3-year overall survival in epithelial ovarian cancer patients.Methods: This study is a retrospective cohort study using medical record of patients with epithelial ovarian cancer registered in cancer registry of Oncology Division in Obstetrics and Gynecology Department, Dr. Cipto Mangunkusumo National General Hospital from January 2014 - July 2016. Data were collected when subjects were first until diseases outcomes identified in 3 years.Results: : Out of 220 subjects, 132 (60%) were patients with advanced stage epithelial ovarian cancer (stage II/III/IV). 94 (42.7%) subjects had thrombocytosis. Patients with advanced stage of disease had higher risk of having thrombocytosis than the ones with earlier stage (p=0.005; OR=2.329). Correlation between thrombocytosis and 3-year overall survival was known to be insignificant (p=0.555). There was shorter mean time survival between patients with thrombocytosis and the ones without but the there was no significant difference in hazard ratio between the two groups (p = 0.399).Conclusion :Thrombocytosis is not a prognostic factor in patients with epithelial ovarian cancer. There is also no significant difference of 3-year overall survival between patients with or without thrombocytosis.Keywords: epithelial ovarian carcinoma, prognosis, thrombocytosis.
Abstrak
Tujuan: Membuktikan bahwa trombositosis sebagai faktor prognosis kesintasan pada pasien kanker ovarium jenis epitelial dan hubungannya terhadap kesintasan 3 tahun pasien kanker ovarium jenis epitelial.Metode: Penelitian ini merupakan studi kohort retrospektif menggunakan data rekam medis pasien kanker ovarium epitelial yang terdaftar pada cancer registry Departemen Obstetri dan Ginekologi Divisi Onkologi Rumah Sakit Cipto Mangunkusumo pada tahun Januari 2014-Juli 2016. Pengamatan dilakukan saat subjek pertama kali didiagnosis akhir pengamatan selama 3 tahun.Hasil: Didapatkan 220 subjek penelitian yang merupakan populasi terjangkau dan memenuhi kriteria inklusi dan eksklusi. Dari 220 subjek penelitian, 132 (60%) dari 220 subjek penelitian merupakan pasien dengan kanker ovarium stadium lanjut (Stadium II/III/IV). Trombositosis didapatkan pada 94 orang subjek penelitian (42,7%). Pasien dengan kanker stadium lanjut memiliki risiko trombositosis yang lebih tinggi dibandingkan subjek pada stadium awal (p=0,005;OR=2,329). Trombositosis secara statistik tidak bermakna pada kesintasan 3 tahun (p=0,555). Terdapat mean time survival yang lebih rendah pada pasien dengan trombositosis tetapi tidak ada perbedaan hazard ratio yang bermakna antara subjek dengan atau tanpa trombositosis (p=0,399).Kesimpulan : Trombositosis bukan merupakan faktor prognostik pada pasien kanker ovarium jenis epitelial dan tidak terdapat hubungan antara trombositosis dan 3 tahun pada pasien dengan kanker ovarium jenis epithelial.Kata kunci: karsinoma ovarium epithelial, prognosis, trombositosi
A Significant Increase in Maternal Blood Uric Acid Levels Accompanies the Severity of Hypertensive Disorders in Pregnancy: Peningkatan Signifikan Kadar Asam Urat Darah Ibu menyertai Keparahan Gangguan Hipertensi pada Kehamilan
Get PDFObjective: To asses the relationship between maternal serum uric acid level and severity of hypertensive disorders in pregnancy and perinatal outcomes.Methods: A cross sectional study was conducted at Persahabatan Hospital from January 2014 to December 2018. Subject were pregnant women with hypertensive disorder. Serum uric acid levels were taken from a venous blood sample at the time the patient came for delivery. The severity of hypertensive disorders in pregnancy were grouped into chronic hypertension, gestational hypertension, preeclampsia without severe feature, preeclampsia with severe feature, and preeclampsia with severe feature and organ involvement. The perinatal outcomes were the gestational age at birth, birth weight, and the first minute APGAR score. The relationship between maternal serum uric acid level and severity of hypertensive disorders in pregnancy and perinatal outcomes were analyzed using Mann Whitney and Kruskall Wallis test.Result: A total of 704 out of 880 pregnant women with hypertensive disorder have met the criteria as research subjects. Maternal uric acid levels were found to increase significantly (p <0.001) with increasing severity of hypertensive disorders in pregnancy. Maternal who experienced preterm delivery had significantly higher blood uric acid levels (p <0.001) than those who experienced a term delivery. Maternal blood uric acid levels of infants with small birth weight for gestational age and first minute Apgar score <7 were slightly higher but not significant compared to maternal blood uric acid levels of normal birth weight infants and first minute Apgar score >7.Conclusions: Maternal blood uric acid levels increased significantly accompanying the severity of hypertensive disorders in pregnancy. Blood uric acid levels tend to be higher in maternal who have poor perinatal outcomes.Keywords: APGAR score, hypertensive disorders in pregnancy, preeclampsia, uric acid.
AbstrakTujuan: Untuk menilai hubungan antara kadar asam urat serum ibu dan keparahan gangguan hipertensi pada kehamilan dan luaran perinatal.Metode: Studi potong lintang dilakukan Rumah Sakit Persahabatan periode Januari 2014 sampai Desember 2018. Subjek penelitian adalah ibu hamil dengan gangguan hipertensi. Kadar asam urat darah diambil dari sampel darah vena pada saat ibu hamil datang untuk melahirkan. Tingkat keparahan gangguan hipertensi pada kehamilan dikelompokkan menjadi hipertensi kronik, hipertensi gestasional, preeklamsia tanpa gejala berat, preeklamsia dengan gejaka berat, dan preeklamsia dengan gejala berat dan keterlibatan organ. Luaran perinatal adalah usia kehamilan saat lahir, berat badan bayi lahir, dan skor APGAR menit pertama. Hubungan antara kadar asam urat darah ibu dan tingkat keparahan gangguan hipertensi pada kehamilan dan luaran perinatal dianalisis menggunakan uji Mann Whitney atau uji Kruskall Wallis.Hasil: Sebanyak 704 dari 880 ibu hamil penderita hipertensi telah memenuhi kriteria sebagai subjek penelitian. Kadar asam urat darah ibu meningkat secara signifikan (p <0,001) dengan meningkatnya keparahan gangguan hipertensi pada kehamilan. Ibu yang melahirkan preterm memiliki kadar asam urat darah yang lebih tinggi secara bermakna (p < 0,001) dibandingkan ibu yang melahirkan aterm. Kadar asam urat darah ibu dari bayi dengan berat lahir kecil untuk usia kehamilan dan skor Apgar menit pertama < 7, sedikit lebih tinggi tetapi tidak signifikan, dibandingkan kadar asam urat darah ibu dari bayi berat lahir normal dan skor Apgar menit pertama pertama > 7.Kesimpulan: Kadar asam urat darah ibu meningkat secara signifikan menyertai beratnya gangguan hipertensi pada kehamilan. Kadar asam urat darah cenderung lebih tinggi pada ibu yang memiliki luaran perinatal kurang baik.Kata kunci: APGAR, asam urat, hipertensi dalam kehamilan, preeklamsia
Risk Factors of Postpartum Urinary Retention: Faktor Risiko Retensio Urine Pascasalin
Get PDFObjective: To determine the correlation between risk factors and the incidence of postpartum urinary retention (PUR) at RSUP Dr. Mohammad Hoesin Palembang. Method: Analytical observational study with cross sectional design to find out the correlation between risk factors and incidence of PUR at emergency room, delivery room and ward at dr. Mohammad Hoesin General Hospital Palembang since October 2018 to April 2019. There were 82 samples that met inclusion criteria. The correlation between risk factors and the incidence of urinary retention was analyzed using Chi Square test/ Fisher Exact test, and the most important risk factor was determined using the Logistic Regression test. Data analysis used SPSS version 22.0. Result: In this study, it was found that there was a significant relationship between prolonged second stage of labor (PR=40.75, p=0.000), type of labor (PR=9.028 CI 95% 2.114–38.558; p=0.004 ) and perineal laceration (PR=12.938 CI95% 1.872–89.414; p=0.016) with PUR. However, there was no significant relationship between age, parity, neonatal birth weight, episiotomy, vulvar edema and urinary retention (p>0.05). It was concluded that instrumental delivery had a significant effect on the incidence of urinary retention (PR=13,541 CI95% 2.381–77.018, p value=0.003) by using logistic regression test.Conclusion: The most important risk factor of urinary retention was instrumental delivery.Keywords: instrumental delivery, perineal laceration, postpartum urinary retention, type of labor
Abstrak
Tujuan: Untuk mengetahui hubungan antara faktor risiko dan kejadian retensio urine pascasalin di RSUP Dr. Mohammad Hoesin Palembang.Metode: Penelitian observasional analitik dengan desain potong lintang untuk mengetahui hubungan antara faktor risiko dan kejadian retensio urine pascasalin di IGD, kamar bersalin dan bangsal perawatan RSUP Dr. Mohammad Hoesin Palembang sejak Oktober 2018 sampai April 2019. Didapatkan 82 sampel yang memenuhi kriteria inklusi. Hubungan antara faktor risiko dan kejadian retensio urine dianalisis menggunakan uji Chi Square/Fisher Exact, sedangkan untuk mengetahui faktor risiko yang paling berperan menggunakan uji regresi logistik. Analisis data menggunakan SPSS versi 22.0.Hasil: Pada penelitian ini, didapatkan hubungan yang signifikan antara lama kala II (PR=40,75, p=0,000), jenis persalinan (PR=9,028 IK95% 2,114–38,558; p=0,004), laserasi perineum (PR=12,938 CI95% 1,872–89,414; p=0,016), dan retensio urine pascasalin. Namun, didapatkan hubungan yang tidak signifikan antara usia, paritas, BBL bayi, episiotomi, edema vulva, dan kejadian retensio urin (p>0,05). Dengan uji regresi logistik, didapatkan kesimpulan bahwa jenis persalinan dengan instrumen berpengaruh secara signifikan terhadap kejadian retensio urine (PR = 13,541 IK95% 2,381–77,018, p value = 0,003).Kesimpulan: Faktor risiko yang paling berperan terhadap kejadian retensio urine pascasalin adalah persalinan dengan instrumen.Kata Kunci: jenis persalinan, instrumen, laserasi perineum, retensio urine pascasali
Vaginal Microorganism Pattern in Premature Rupture of Membrane: Pola Mikroorganisme Vagina pada Ketuban Pecah Dini
Get PDFObjective: To determine the pattern of vaginal microorganisms in pregnant women and risk factors for premature rupture of membranes (PROM) in Manado.Methods: This is a case-control study. Samples was 40, divided into 20 pregnant with PROM and 20 control samples. Samples were taken from Kandou Manado Hospital and network hospitals within the inclusion criteria. Samples were taken from vaginal swab for microorganism culture.Results: The highest age distribution in the case of PROM was in the reproductive age group of 20-35 years, 19 people (95%, p = 1,000). Primiparas were dominant in the PROM were 11 people (55%, p = 0.204). The distribution of BMI mostly from the overweight and obesity groups of 11 people (55%, p = 0.527). In the PROM, 19 people (95%, p = 0.605) did not smoke. Escherichia coli was the most microorganisms in swab vaginal of PROM: 7 people (29.17%).Conclusion: The most microorganisms found in PROM are Escherichia coli, Enterobacter cloacae and Staphyloccocus aureus and in non-PROM are Klebsiella oxytoca, Staphylococcus epidermidis, Staphylococcus saprophyticus and Pseudomonas fluorescens. There was no relationship between BMI, age, parity, smoking, and gestational age with the incidence of PROM in this study.Keywords: PROM , vaginal microorganisms pattern, vaginal swab.
Abstrak
Tujuan: Untuk mengetahui pola mikroorganisme vagina pada kultur vaginal swab wanita hamil dan faktor risiko pada KPD di Kota Manado.Metode : Studi ini bersifat case control. Total sampling 40 sampel dibagi menjadi 20 sampel hamil dengan KPD dan 20 kontrol. Sampel diambil dari RSUP Kandou Manado dan RS jejaring yang memenuhi kriteria inklusi. Semua pasien dilakukan pengambilan sampel swab vagina untuk dilakukan kultur mikroorganisme.Hasil : Hasil sebaran usia pada KPD paling banyak pada usia reproduksi 20-35 tahun yaitu 19 orang (95%, p = 1,000). Primipara dominan pada KPD yaitu 11 orang (55%, p = 0,204). Hasil sebaran IMT paling banyak kelompok overweight dan obesitas yaitu 11 orang (55%, p = 0,527). Pada KPD sebanyak 19 orang (95%, p = 0,605) tidak merokok. Mikroorganisme terbanyak pada swab vagina KPD adalah Escherichia coli sebanyak 7 orang (29,17%). Kesimpulan: Mikroorganisme terbanyak pada KPD adalah Escherichia coli, Enterobacter cloacae dan Staphyloccocus aureus dan pada non KPD adalah Klebsiella oxytoca, Staphylococcus epidermidis, Staphylococcus saprophyticus dan Pseudomonas fluorescens. Tidak ada hubungan antara IMT, usia, paritas, merokok, dan umur kehamilan dengan kejadian KPD pada penelitian ini.Kata kunci: pola mikroorganisme vagina, ketuban pecah dini, swab vagina.
 
The Role of Ferritin Levels Serum of Third Trimester Obese Pregnant Women in Neonatal Outcome: Peran Kadar Feritin Serum pada Perempuan Hamil Trimester Tiga dengan Obesitas terhadap Luaran Bayi
Get PDFMaternal and Perinatal Outcomes of COVID-19 in Pregnant Women : Luaran Maternal dan Perinatal pada Ibu Hamil dengan COVID-19
Get PDFObjective: To describe and identify risk factors of maternal and perinatal outcome of COVID-19 in pregnant women.Methods: Literature search was conducted on MEDLINE and Google Scholar databases for articles published in December 2020 to January 2021. Keywords used includes ‘COVID-19’, ‘pregnant women’, ‘maternal outcome’ and ‘fetal outcome.’ Critical appraisal and selection were conducted to identify articles that fulfill inclusion criteria. The selected articles were analyzed thematically to answer the research questions.Results: Literature search yielded 124 articles with 11 included in final analysis. The results showed low to moderate risk of maternal and perinatal adverse outcomes, including low risks for maternal and perinatal mortality coupled with moderate risk for maternal ICU admission and preterm birth with NICU admission for the newborn. Higher risk was observed for pregnant women with symptomatic COVID-19 infection, which points to the necessity for awareness of the risk and targeted early detection efforts.Conclusion: There are low risk for adverse maternal and perinatal outcomes, including mortality and ICU/NICU admission, associated with COVID-19 infection in pregnant women. Risk factors for adverse outcomes included pregnant women with symptomatic COVID-19 infection.Keywords: COVID-19, ICU, maternal mortality, NICU, perinatal mortality, preterm birth
Abstrak
Tujuan: Mendeskripsikan dan mengidentifikasi faktor risiko luaran maternal dan perinatal COVID-19 pada ibu hamil.Metode: Penelusuran literatur dilakukan di database MEDLINE dan Google Scholar untuk artikel yang diterbitkan pada Desember 2020 hingga Januari 2021. Kata kunci yang digunakan meliputi 'COVID-19', 'wanita hamil', 'keluaran ibu' dan 'hasil janin'. Penilaian dan seleksi kritis dilakukan untuk mengidentifikasi artikel yang memenuhi kriteria inklusi. Artikel yang dipilih dianalisis secara tematis untuk menjawab pertanyaan penelitian.Hasil: Penelusuran literatur menghasilkan 124 artikel dengan 11 termasuk dalam analisis akhir. Hasil penelitian menunjukkan risiko rendah hingga sedang untuk luaran buruk maternal dan perinatal, termasuk risiko rendah untuk kematian maternal dan perinatal ditambah dengan risiko sedang untuk masuk ICU ibu dan kelahiran prematur dengan masuk NICU untuk bayi baru lahir. Risiko yang lebih tinggi diamati untuk wanita hamil dengan infeksi COVID-19 bergejala, yang menunjukkan perlunya kesadaran akan risiko dan upaya deteksi dini yang ditargetkan.Kesimpulan: Terdapat risiko rendah untuk laran buruk maternal dan perinatal, termasuk kematian dan rawat inap di ICU/NICU, terkait dengan infeksi COVID-19 pada wanita hamil. Faktor risiko untuk luaran buruk adalah wanita hamil dengan gejala infeksi COVID-19.Kata kunci: COVID-19, ICU, kelahiran preterm, mortalitas maternal, mortalitas perinatal, NIC
Role of TNF-alpha and Interleukin 6 Serum against Ovarian Reserve in Endometriosis Cysts: Peran TNF – a dan Interleukin 6 Serum terhadap Cadangan Ovarium pada Penderita Kista Endometriosis
Get PDFObjective: To investigate the correlation between proinfl ammatory factors (TNF-alpha and IL-6) with ovarian reserve in patients with endometriosis cysts.
Methods: This is a cross sectional study. The number of samples is 25 people. Sampling technique consecutive sampling. The study began in June 2019 until the number of samples was fulfi lled at the Obstetrics and Gynecology Polyclinic of the Dr. General Central Hospital M. Djamil Padang and at the Biomedical Laboratory of the Faculty of Medicine, Andalas University, Padang. To determine the correlation of TNF-alpha, IL-6, and AMH in patients with endometriosis cysts. Examination of TNF-alpha, IL-6, and AMH levels was carried out in a quantitative manner, using the ELISA method.Result: The mean AMH level was 2 ± 0.40 pmol / L andTNF-alpha level was 11.16 ± 4.79 pg / ml. Correlation of AMH level with TNF-alpha indicates the value of r = -0.049 which has weak strength and negative pattern means that the higher the TNF-alpha level, the lower the AMH level. The analysis showed that there was no correlation between TNF-alpha levels and AMH levels in patients with endometriosis cysts (p>0.05). Correlation of AMH levels with IL-6 shows the value of r = 0.35 which has moderate strength and positive pattern means that the higher the IL-6 level, the higher the AMH level. The analysis showed that there was no correlation between IL-6 levels and AMH levels in patients with endometriosis cysts (p> 0.05).
Conclusions: There is a negative correlation of TNF-alpha levels with AMH levels in patients with endometriosis cysts, namely the higher TNF-alpha levels, the lower AMH levels and there is a positive correlation of IL-6 levels with AMH levels in patients with endometriosis cysts. Where the higher levels of IL-6, the higher levels of AMH.
Keywords: AMH, endometriosis, TNF-alpha, IL-6