Indonesian Journal of Obstetrics and Gynecology (INAJOG)
Not a member yet
904 research outputs found
Sort by
Unraveling Of Urinary Disorders to Adenomyosis and Dysmenorrhea
Full text linkObjective : This study aims to explore the relationship between micturition disorders and adenomyosis and dysmenorrhea and provide insight into the factors associated with the severity of LUTS symptoms in these conditions.
Methods : This study was a descriptive qualitative study. We retrospectively collected medical record data from the Obstetrics Gynecology Outpatient Ward of Dr. Moewardi Surakarta General Hospital in the period January 2021 to May 2023. The results of this study analyzed using Pearson correlation analysis if normally distributed and using Mann-Whitney if not normally distributed, thus, statistically analyzed.
Results: There is a significant relationship between adenomyosis and dysmenorrhea on urinary disorders (p value of 0.016) where urinary disorders are found to be more severe in adenomyosis patients with dysmenorrhea.
Conclusion : Lower urinary tract symptoms are common in symptomatic adenomyosis patients and greatly affect the patient's quality of life. Dysmenorrhea can be a potential risk factor that increases the occurrence of moderate to severe LUTS.
Keywords: adenomyosis; dysmenorrhea; urinary disturbance
The Age as a Risk Factor for Advanced Stage in Cervical Cancer Patients at RSUPN Cipto Mangunkusumo 2019-2022: A Retrospective Multivariate Study
No full textAbstract
Introduction: In 2020, cervical cancer ranked as the fourth most common cancer in women globally, with an incidence of 604,000 cases. In Indonesia, cervical cancer holds the second position among the most prevalent cancers in women. This study aims to evaluate the relationship between age and the occurrence of advanced-stage cervical cancer as a step towards effective prevention, early detection, and management. Methods: This research adopts a retrospective study design based on the Cancer Registration database of RSUPN Cipto Mangunkusumo, focusing on cervical cancer patients from 2019 to 2022. Multivariate analysis was conducted with age as the primary independent variable, considering parity and employment status in the analysis. The FIGO classification of cervical cancer stages was used to categorize patients into early and advanced stages. Results: Out of 512 cervical cancer cases, 492 were included in this study. The distribution of cervical cancer stages and the age distribution of patients is depicted in Figure 1 and Figure 2. The analysis of the relationship between cervical cancer stage, age, parity, and employment status is presented in Table 2. The association between age and cervical cancer stage is statistically significant (p<0.05) with an odds ratio of 2.13, particularly in individuals aged >54 years. Conclusion: Age over 54 years is a significant risk factor for advanced-stage cervical cancer. Although there is no significant association with parity and employment history, these findings support preventive and early detection efforts in the older population. Increased screening programs and education are expected to reduce cases of advanced-stage cervical cancer in the future
Leptin Expression in High-grade Serous Ovarian Carcinoma: The Controversy of Leptin Paradox in Ovarian Cancer
Full text linkObjectives : To analyse the characteristics and expression patterns of Leptin in high-grade serous epithelial ovarian carcinoma (HGSC), and to compare them with the overall serous ovarian carcinoma population.
Methods : This was a cross-sectional study. A total of 77 paraffin-embedded tissue samples were collected from patients at the Wahidin Sudirohusodo Hospital over a period of 3 years. Immunohistochemical staining was performed using a polyclonal Leptin antibody. Data were analyzed using SPSS version 22.0.
Results: Among HGSC patients, the majority (64.3%) were over 50 years old, and a significant portion (39.3%) were obese. Leptin showed strong cytoplasmic expression in 69.6% of HGSC tumor cells and in 100% of LGSC tumor cells (p-value = 0.004). There was no correlation between lymphovascular space invasion and leptin expression. Interestingly, leptin expression in overall serous ovarian carcinoma patients exhibited a protective effect against metastasis (p-value = 0.047), suggesting a leptin paradox exists in this type of cancer. However, this association was no longer significant when the analysis excluded the LGSC group (p-value = 0.193).
Conclusion : This study suggest that leptin expression may not be a significant prognostic factor in HGSC. The appearance of the pseudo-leptin paradox phenomenon in several previous studies was confounded by sample populations with heterogeneous tumor morphology.
Keywords: high-grade serous carcinoma, leptin paradox, immunohistochemistry, leptin, obesit
Impact of Attending Prenatal Yoga Classes on Prepartum Maternal Mental Health : A Quasi-Experimental StudyI: Prenatal Yoga Classes on Maternal Mental Health
No full textINTRODUCTION Anxiety from the imagination of childbirth pain and fear of childbirth in pregnant mothers. Fear of childbirth has been associated with prolonged labor, childbirth complications that increased postpartum depression.
OBJECTIVE : This study aimed to determine the effect of prenatal classes on mental health.
METHODS The research design was a quasi-experiment of two groups with pre-test and post-test design. The sample was pregnant women who met the inclusion and exclusion criteria. A total of 106 participants were divided into two groups: intervention, and control group. The research instrument was a questionnaire. The ANOVA test was used to analyze the data.
RESULT The average mental health score of the intervention group was higher (84.04) than that of the control group (67.32), with a p-value <0.001.
CONCLUSIONS This study concludes that yoga prenatal classes improve positive mental health status
Keywords: Pregnant Women; Yoga Prenatal Class; Mental Health
INTRODUCTION Anxiety from the imagination of childbirth pain and fear of childbirth in pregnant mothers. Fear of childbirth has been associated with prolonged labor, childbirth complications that increased postpartum depression.
OBJECTIVE : This study aimed to determine the effect of prenatal classes on mental health.
METHODS The research design was a quasi-experiment of two groups with pre-test and post-test design. The sample was pregnant women who met the inclusion and exclusion criteria. A total of 106 participants were divided into two groups: intervention, and control group. The research instrument was a questionnaire. The ANOVA test was used to analyze the data.
RESULT The average mental health score of the intervention group was higher (84.04) than that of the control group (67.32), with a p-value <0.001.
CONCLUSIONS This study concludes that yoga prenatal classes improve positive mental health status
Keywords: Pregnant Women; Yoga Prenatal Class; Mental Healt
Current Trends in Contraceptive Use and Fertility Concerns Among Women of Reproductive Age in Indonesia
Full text linkAbstract
Background
Family planning remains a key intervention in reducing maternal mortality and creating prosperous families. Assessing the unmet need for family planning allows insight into the progress of family planning programs. On the other hand, there has been much less attention given to the declining fertility rate in Indonesia. To address both the unmet need and declining fertility rate in Indonesia, this study aimed to investigate the most recent trends in contraceptive use in Indonesia as well as evaluate fertility concerns and access to reproductive healthcare service.
Methods
Women of reproductive age in Indonesia were asked to fill in an online questionnaire. They were asked about sociodemographic characteristics, marital status, pregnancy history, perception towards fertility, and access to healthcare service and information. Descriptive statistics and independent t-test were performed.
Results
Of 370 women, more than half (57.8%) had used some form of contraception. The most frequently used contraceptive method was natural family planning (30.3%), followed by condom (20%). Women with no prior sexual history, had never been pregnant before, and had not been married cared more about having a child in the future. Internet and social media represented the most popular information source for family planning.
Conclusions
Many Indonesian women still prefer traditional contraceptive methods over the more effective modern contraceptive methods. Numerous socio-cultural factors are likely to influence the behaviour of reproductive-age women regarding contraceptive use and childbearing in the future. More effort should be put into raising awareness about modern contraceptive methods and addressing fertility concerns.
Keywords: contraception; fertility; family planning; awareness; reproductio
Usability, Acceptability, and Satisfaction of Indonesian Birth Attendant Practitioners Using the 2020 World Health Organization Labor Care Guide
No full textObjectives: This study was conducted to determine whether the World Health Organization Labor Care Guide 2020 (WHO LCG 2020) can be accepted and implemented by Indonesian birth attendant practitioners.Methods: This study is mixed-method research, with a quantitative study using a cross-sectional design and a qualitative study using an in-depth interview design. The study was conducted from July to November 2023 in Dr. Cipto Mangunkusumo General Hospital and associated teaching hospital. The subjects in this study were birth attendant practitioners who had received training in the use of partographs or normal delivery care (APN). Data analysis was performed descriptively to determine the distribution and characteristics of practitioners and patients, which will be presented in a tabular form. Data from the interviews were reported narratively.Results: Fifty-nine participants (45 midwives and 14 doctors) received training in the use and filling of the LCG sheet. The participants used the LCG for 120 patients, with the majority of patients having spontaneous vaginal births (78.3%). From the results of the questionnaire, 40 participants (67.8%) felt that the LCG sheet was useful and 42 participants (71.2%) felt satisfied. Overall, most participants felt that the LCG sheet was useful and satisfied with its use in helping health workers assist in childbirth.Conclusion: It was found that regular training is needed on how to complete the WHO LCG 2020 sheet, and a lot of experience is required to become accustomed to using the LCG new birth monitoring format. Keywords: birth attendant, childbirth, doctors, labor care guide, midwive
Vaginal Microbial Patterns and Matrix Metalloproteinase-9 Levels in relation to Premature Rupture of Membranes
Full text linkIntroduction: The premature rupture of membranes (PROM) before the onset of labor, characterized by the painless leakage of fluid from the vagina, can lead to fetal distress and increase the risk of cesarean section. This study analyzed the microbial patterns and matrix metalloproteinase 9 (MMP-9) levels in cases of PROM.
Methods: This was an observational study with cross-sectional design. Samples were collected from 60 pregnant women diagnosed with PROM who underwent examination and treatment at St. Khadijah I Hospital in Makassar in November 2023. Statistical analysis was performed using the Independent Samples T-Test for microbial patterns and MMP-9 levels.
Results: The MMP-9 level in PROM group was significantly higher (1706,78 ± 386,36) compared to non-PROM group (1328,20 ± 1556,22) with p = 0.006. For microbial pattern, E. coli was the predominant bacteria in PROM group (72,0%) compared to non-PROM group (28,0%) with p = 0.004.
Conclusion: The results of this study indicate that high MMP-9 level and predominant E. coli presence in the vaginal swab may increase the risk of PROM
From Diagnosis to Management: A Rare Case of Disseminated Low-Grade Endometrial Stromal Sarcoma with Extensive Extrauterine Spread
Full text linkObjective: To report a rare case of low-grade endometrial stromal sarcoma; which was found not only in the uterus but also in several extrauterine sites, such as the ovary, omentum, and jejuno-ileum. In this article, we provided the management performed, based on appropriate literatures.
Methods: Case report.
Case: A 44-year old para 2 complained of abdominal enlargement since 3 months. Patient also complained of pelvic pain. The patient has never received treatment before and has never been diagnosed with endometriosis. Abdominal examination revealed a 20-cm mass in the lower to umbilical region and positive shifting dullness. Bimanual pelvic examination revealed immobile and smooth masses in both sides of adnexa, with pain during palpation. Computerized tomography (CT) scan of the abdomen revealed complex cystic masses suspected for right and left ovaries-origin (±11 & 15 cm respectively) Surgical resection and staging, frozen section, cytology examination, and immunohistochemistry (IHC) test were performed, revealing consistent result of endometrioid stromal sarcoma, low grade. Five-months postoperative follow-up through abdominal CT-scan in the patient revealing no abnormalities.
Conclusion: We know that LG-ESS is one of the rare types of endometrial stromal sarcoma. Moreover in this case extrauterine manifestations make it more challenging in clinical management. Risk factors and history of endometriosis are important to explore when meeting ESS cases. Further research needs to be done regarding the exact mechanism and the association between endometriosis or other risk factors and the development of ESS, especially the EESS type to allow intervention.
Keywords: uterine sarcoma, endometrial stromal sarcoma, management
Therapy of Dequalinium Chloride Vaginal Tablets in Pregnant Women with Vulvovaginal Candidiasis
No full textBackground: Vulvovaginal candidiasis (VVC) is a Candida infection on vulva and vagina region. The most common etiology is C. albicans. Besides being the risk factor for developing VVC, pregnancy also limits the possible medication. This report presents the efficacy of Dequalinium Chloride (DQC) on VVC during pregnancy due to C. albicans.
Case: A third-trimester primigravidae, 27-year-old, complained first odorless thick curd-like consistency vaginal discharge accompanied with pruritus (VAS 9/10) and pain since 3 months prior to admission. Venerology examination showed erythema on the labia majora and a great amount of thick vaginal discharge on the labia minora, vaginal, and cervix area. Vaginal discharge examination using KOH 10% showed pseudohyphae. Gram examination found pseudohyphae and polymorphonuclear (PMN) cells >30 in the vagina, and pseudohyphae on the cervix’s discharge. VITEK-2 culture showed fluconazole-sensitive C. albicans. The patient was given DQC intravaginal tablets for 10 days and showed remarkable clinical and microscopic examination improvement.
Conclusion: Intravaginal DQC is effective in treating pregnant patients with VVC. VVC in pregnancy should be treated appropriately to prevent perinatal adverse effects.
Keywords: Vulvovaginal Candidiasis, dequalinium chloride, pregnancy, C. albican
Management of Severe Preeclampsia with Anemia in Pregnant Women with Covid-19 Infection : A Multidisciplinary Approach
Full text linkCoronavirus disease 2019 (COVID-19) is a disease that is currently pandemic almost worldwide, with the first case in Indonesia on March 2, 2020, spreading rapidly across the entire country. Pregnant women are a vulnerable group to experience health disorders, especially infectious diseases, due to changes in physiological body and immune response mechanisms within their bodies. In this study, we report a case of COVID-19 in a 31-year-old pregnant woman at 30-31 weeks of gestation, who is pregnant with her second child and complained of leaking amniotic fluid and shortness of breath. Physical examination results showed: positive SARS-CoV-2 antigen swab test, BP 156/112 mmHg, T (36.0°C), heart rate 107 beats per minute, respiratory rate 30 breaths per minute, fetal heart rate 144 beats per minute, SpO2 97%, urine protein +4, Hb 4.4 g%. Vaginal toucher examination revealed cervical dilation of 1 cm, negative for amniotic fluid leakage, and cephalic presentation. Spontaneous delivery process. The baby was born normally, female, APGAR score 1-2, weight 900 grams, length 27 cm, positive anus. Complications accompanying pneumonia, metabolic acidosis, anemia, melena, coagulopathy. This case report contains clinical descriptions, diagnosis, and management of care for pregnant women with Covid-19.