Indonesian Journal of Obstetrics and Gynecology (INAJOG)
Not a member yet
904 research outputs found
Sort by
Effect Knowledge and Attitude with Behaviour of HPV Vaccination in Women of Reproductive Age: Pengaruh Pengetahuan dan Sikap dengan Perilaku Vaksinasi HPV pada Wanita Usia Reproduksi
Full text linkTo observe the association between knowledgeand attitude towards HPV vaccination with the behaviortowards HPV vaccination on reproductive woman inIndonesia.Methods: We conducted observational analytic studywith cross-sectional design. The study was conducted inobstetric and gynecologic outpatient clinic in Prof. Dr. R.D. Kandou General Hospital, Manado Indonesia throughJuly and August 2021. Reproductively active woman wereincluded as the subject. Univariate and bivariate analysiswere conducted in this study.Results: We included 364 reproductive woman. The majorityof the subject were 20-35 year-old woman (50.8%) and weremarried (61.3%). The majority of the subject (72.8%) havereceived information about HPV vaccination. We foundsignificant association between knowledge and attitudewith the OR of 5.57 (p=0.00). Knowledge and attitudeshowed significant association with eagerness towards HPVvaccination. However, knowledge and behavior did notshow any significant association towards HPV vaccinationbehavior.Conclusion: There is a significant association betweenknowledge and attitude of HPV vaccination with eagernesstoward HPV vaccination in reproductive women in Indonesia.Keywords: behavior, HPV vaccination, knowledge,reproductive women.
Keywords: behavior, HPV vaccination, knowledge,reproductive women.
AbstrakTujuan: Untuk mengetahui hubungan pengetahuan dansikap terhadap perilaku vaksinasi HPV pada perempuan usiareproduktif di RSUP Prof. DR. R. D. Kandou, Manado.Metode: Penelitian ini merupakan penelitian analitikobservasional dengan pengambilan subjek potong lintang.Penelitian dilakukan di unit pelayanan bagian Obstetri danGinekologi RSUP Prof. Dr. R. D. Kandou Manado pada Juli-Agustus 2021. Subjek penelitian merupakan perempuanusia reproduktif yang bersedia untuk mengikuti penelitianini. Analisis data akan dilakukan secara univariat dan bivariatserta dilaporkan pada penelitian ini.Hasil: Penelitian ini mencakup 364 perempuan dengan usiaproduktif. Mayoritas subjek merupakan perempuan denganusia 20-35 tahun (50,8%) dan sudah menikah (61,3%).Mayoritas subjek (72,8%) pernah mendapatkan informasivaksinasi HPV sebelumnya. Hubungan antara pengetahuandan sikap terhadap vaksinasi menunjukkan hasil yangsignifikan (p=0,00) dengan OR 5,57. Pengetahuan dansikap juga menunjukkan hubungan yang signifikan dengankesediaan vaksin (p<0,05). Pengetahuan dan sikap tidakmenunjukkan hubungan yang bermakna terhadap perilakuvaksin (p>0,05).Kesimpulan: Terdapat hubungan yang bermakna antarapengetahuan dan sikap dengan perilaku keinginan vaksinasiHPV pada perempuan usia reproduktif.Kata kunci: pengetahuan, perempuan usia reproduktif,sikap, Vaksinasi HPV.
 
Ovarian Reservation in Women with Ovarian Endometriosis Cyst after Laparoscopic Cystectomy and Leuprorelin Acetate Administration: Cadangan Ovarium pada Perempuan dengan Kista Endometriosis Ovarium setelah Laparoskopi Kistektomi dan Leuprorelin Asetat
Full text linkObjective: To determine differences in ovarian reserve in women with ovarian endometrial cysts after laparoscopic cystectomy and leuprorelin acetate administrationMethods: Single cohort prospective pre and post-test design study with 25 research subjects. The independent variables were interventional laparoscopic cystectomy, and leuprorelin acetate administration. The dependent variable is ovarian reserve as measured by AMH levels.Results: The research subjects had a mean age of 31 years and a BMI of 23.55 kg/m2. There were 8 subjects with unilateral cysts and 17 subjects with bilateral cysts. Preoperative AMH levels had a median value of 1.32 ng/mL (0.88-5.13), postoperative AMH levels had a median value of 1.07 ng/mL (0.60-4.53), and postoperative AMH levels + Leuprorelin Acetate injection had a median value of 1.06 ng/mL (0.50-4.65). There was a significant difference between preoperative AMH and postoperative AMH (p<0.001). There was no significant difference between postoperative AMH and postoperative AMH + Leuprorelin Acetate injection (p=0.149). BMI has a relationship (p=0.048) with pre-operative AMH levels with a weak and opposite relationship (r= -0.399).Conclusion: There was a statistically significant 18.9% decrease between pre-operative post-operative AMH levels. Body Mass Index (BMI) and pre-operative AMH levels are associated with one another.Keywords: anti-müllerian hormone, leuprorelin acetate, ovarian cystectomy, ovarian reserve.AbstrakTujuan: Mengetahui perbedaan cadangan ovarium pada perempuan dengan kista endometrium ovarium setelah laparoskopi kistektomi dan injeksi leuprorelin asetat.Metode: Desain penelitian pre dan post-test prospektif kohort tunggal dengan 25 subjek penelitian. Variabel bebas adalah intervensi laparoskopi kistektomi, dan injeksi leuprorelin asetat. Variabel terikat adalah cadangan ovarium yang diukur dengan kadar AMH.Hasil: Subjek penelitian memiliki rerata usia 31 tahun dan IMT 23,55 kg/m2. Terdapat 8 subjek dengan kista unilateral, 17 subjek dengan kista bilateral. Kadar AMH praoperasi memiliki nilai median 1,32 ng/mL (0,88-5,13), kadar AMH pascaoperasi memiliki nilai median 1,07 ng/mL (0,60-4,53), dan kadar AMH pascaoperasi + injeksi Leuprorelin Asetat memiliki nilai median 1,06 ng/mL (0,50-4,65). Ada perbedaan yang signifikan antara AMH pra operasi dan AMH pascaoperasi (p<0,001). Tidak ada perbedaan bermakna antara AMH pascaoperasi dengan injeksi AMH + Leuprorelin Asetat pascaoperasi (p=0,149). IMT memiliki hubungan (p=0,048) dengan kadar AMH pra operasi dengan hubungan yang lemah dan berlawanan (r= -0,399).Kesimpulan: Terdapat penurunan 18,9% antara tingkat AMH pra-operasi dan tingkat AMH pasca-operasi yang signifikan secara statistik. Ada hubungan antara BMI dan tingkat AMH pra-operasiKata kunci: cadangan ovarium, hormon anti-müllerian, kistektomi ovarium, leuprorelin asetat
Management of Spontaneous Cornual Heterotopic Pregnancy in Low-Resources Setting: Tata Laksana Kehamilan Heterotopik Kornual Spontan pada Keadaan Sumber Daya Terbatas
Full text linkObjective: To report management of spontaneous cornualheterotopic pregnancy in low-resources setting in EndeDistrict, Flores, East Nusa Tenggara.Methods: Case report.Case: A 34 year old primigravida with history of 8-9 weeksamenorrhea came to Obstetrics ER with chief complaintof vaginal bleeding and lower abdominal pain. Ultrasoundshows intrauterine pregnancy (IUP), an ectopic pregnancy(EP) in right uterine cornu, and free fl uid in hepatorenalspace, splenorenal space, and pouch of douglas suggestingthe occurrence of hemoperitoneum and heterotopicpregnancy. We performed cornual resection by laparotomyand administered progesterone orally before and after thesurgery. Successful outcome was achieved.Discussion: Heterotopic pregnancy (HP) rarely occurs,especially in natural conception. Thus, early diagnosis andtreatment of HP are quite a challenge for physicians especiallyin rural area. Due to the condition of our patient and limitedresources, laparotomy was conducted to remove the EP,rather than laparoscopy despite its advantage to lower riskof IUP abortion. Progesterone was then administered orallyto prevent threatened abortion of the IUP.Conclusion: Despite its challenge in diagnosing andtreating HP, it is a life-threatening condition that requiresaccurate and prompt treatment. The treatment goal is toremove the EP and preserve the IUP. Treatment of choiceshould be decided by takeing the patient’s condition andavailability of resources into account. Surgical along withadministration of progesterone before and after the surgerywould likely improve the outcome of the patient and theintrauterine pregnancy.Keywords: cornual resection, heterotopic pregnancy,laparotomy, low-resources setting, progesterone.AbstrakTujuan: Untuk membahas tentang penatalaksanaankehamilan heterotopik kornu spontan di daerah dengansumber daya rendah khususnya di Kabupaten Ende, Flores,Nusa Tenggara Timur.Metode: Laporan KasusKasus: Seorang perempuan primigravida usia 34 tahundengan riwayat amenore minggu ke-8 dan 9 datang keIGD Obgyn dengan perdarahan pervaginam dan nyeriperut bagian bawah. Temuan USG menunjukkan kehamilanintrauterin (KIU), kehamilan ektopik (KE) di tanduk rahimkanan, dan cairan bebas di ruang hepato-renal, splenorenal,dan cavum douglas. Hal ini menunjukkan terjadinyahemoperitoneum dan kehamilan heterotopik. Reseksikornu dengan laparotomi dilakukan dan pasien diberikanprogesteron secara oral sebelum dan setelah operasi.Luaran baik berhasil dicapai.Diskusi: Kehamilan heterotopik jarang terjadi, terutamapada konsepsi alami. Sehingga diagnosis dan tata laksanaKH sejak dini menjadi tantangan bagi para dokter, terutamadi daerah terpencil Karena kondisi pasien dan sumber daya,laparotomi dilakukan untuk mengangkat KE, daripadalaparoskopi meskipun keuntungannya dalam menurunkanrisiko keguguran KIU. Progesteron kemudian diberikansecara oral untuk mencegah terjadinya keguguran terancamdari KIU.Kesimpulan: Terlepas dari tantangan untuk diagnosisdan tatalaksananya, KH adalah kondisi yang mengancamjiwa yang membutuhkan penanganan yang akurat dansegera. Tujuan tatalaksananya adalah untuk mengangkatKE dan mempertahankan KIU. Pilihan tata laksana harusdiputuskan dengan mempertimbangkan kondisi pasien danketersediaan sumber daya. Pendekatan bedah dan obatdengan progesteron yang diberikan sebelum dan sesudahoperasi akan meningkatkan kemungkinan luaran pasien dankehamilan intrauterine yang baik.Kata kunci: kehamilan, heterotopik, laparotomi,progesteron,reseksi kornual, sumber daya rendah
Neuroendocrine Cervical Carcinoma: Karsinoma Serviks Neuroendokrin
No full textObjective: To present a series of neuroendocrine cervical carcinoma, a rare malignancy of the cervix with different stages, treatment approach and outcome. It is included in this article review about diagnostic approach, treatment and prognosis in dealing with neuroendocrine cervical carcinoma.
Methods: Case report
Cases: We reported three cases of neuroendocrine cervical carcinoma. First is a 40-year old woman para 2, with stage IIIB neuroendocrine cervical carcinoma and chose palliative care only. Second, a 54-year old woman, para 5 with stage IIB neuroendocrine cervical carcinoma which underwent radiotherapy, with a 4 months disease free period. And lastly, a 36-year old woman, para 2 with stage IB1 neuroendocrine cervical carcinoma, underwent a radical abdominal hysterectomy procedure with pelvic lymphadenectomy and external pelvic radiotherapy. The disease is well controlled and had no recurrence in 15 years.
Conclusion: It is important to differentiate neuroendocrine cervical carcinoma with other malignancies that could be found in the cervix. Immunohistochemistry (IHC) tests could be used to achieve that purpose. It is also important to arrange a treatment plan to treat these malignancies and multimodality treatment is preferable for better outcomes.
Keywords: Neuroendocrine cervical carcinoma, cervical carcinoma, multimodality treatment.AbstrakTujuan: Melaporkan serangkaian kasus neuroendocrinecervical carcinoma, salah satu jenis keganasan langka padaarea serviks dengan stadium, tata laksana, dan hasil yangberbeda. Dalam artikel ini juga terdapat ulasan mengenaiprosedur diagnosis, manajemen, dan prognosis darineuroendocrine cervical carcinoma.Metode: Laporan kasusKasus: Artikel ini melaporkan tiga kasus. Pertama perempuan40 tahun riwayat partus dua kali dengan karsinoma serviksneuroendokrin stadium IIIB dan hanya memilih perawatanpaliatif. Kasus kedua, perempuan 54 tahun, riwayat partuslima kali dengan karsinoma serviks neuroendokrin stadiumIIB. Pada pasien dilakukan terapi radiasi dan didapatkankondisi bebas penyakit selama 4 bulan. Terakhir, pasienperempuan 36 tahun riwayat partus dua kali dengankarsinoma serviks neuroendokrin stadium 1B1. Dilakukanhisterektomi radikal dan limfadenektomi kelenjar limfepelvis serta terapi radiasi. Kondisi pasien terkontrol dantidak terdapat kekambuhan setelah 15 tahun.Kesimpulan: Karsinoma serviks dengan jenis neuroendokrinharus dibedakan dengan keganasan lain pada daerah serviks.Uji imunohistokimia dapat digunakan untuk membedakanhal tersebut. Selain itu, penyusunan rencana tatalaksanauntuk mengatasi keganasan pada serviks juga harusmenjadi perhatian penting bagi klinisi. Direkomendasikanuntuk menerapkan tata laksana multimodal untuk mencapaihasil terapi yang optimal.Kata kunci: karsinoma serviks, karsinoma serviksneuroendokrin, tata laksana multimodal
The Effect of Water Intake during Pregnancy on Birth Weight: Pengaruh Asupan Air selama Kehamilan pada Berat Lahir Bayi
No full textAbstractObjective: This systematic review aimed to investigate theeffect of water intake during pregnancy on infant birthweight.Methods: A comprehensive search was conducted usingthe keywords "water intake," "dehydration," "pregnancy,""outcome," "hydration," "birth weight," and "birth outcome"in databases such as "SCOPUS," "EBSCO," "PUBMED,""COCHRANE," and through "Google Search." MeSH headings"pregnancy" and "hydration" were used for the search.Inclusion criteria encompassed pregnant women withoutpathological disorders, birth weight as a studied outcome,prospective cohorts, clinical trial study designs, and Englishlanguagepapers. Out of the 254 articles retrieved, six metthe specifi ed requirements and were included in this review.Results: The fi ndings from the six studies consistentlydemonstrated a positive correlation between higher waterintake, improved hydration, and increased birth weight.All studies measured water consumption or hydrationstatus between 8-37 weeks of gestation. Regardless of theduration of the studies, underhydration or low water intakewas consistently associated with lower birth weight.Conclusion: This review highlights that increasing waterintake among pregnant women positively affects infantbirth weight. Adequate water intake during pregnancy isrecommended to be in the range of 2180 – 3000 mL daily,considering hydration status and the stage of pregnancy.Keywords: birth weight, hydration, pregnancy, water intake.AbstrakTujuan: Untuk mengungkap pengaruh asupan air selamakehamilan terhadap berat lahir bayi.Metode: Menggunakan kata kunci “water intake,""dehydration," "pregnancy," "outcome," "hydration," "birthweight," dan "birth outcome,", artikel dicari. Data diambil daridatabase "SCOPUS," "EBSCO," "PUBMED," "COCHRANE,"dan "Google Search". Kami menggunakan MeSH headingskehamilan dan hidrasi untuk istilah pencarian. Kriteria inklusiadalah perempuan hamil tanpa kelainan patologis, beratbadan lahir adalah salah satu luaran penelitian, desain studiberupa kohort prospektif dan uji klinis, serta artikel dalambahasa Inggris. Dari 254 artikel yang diperoleh, enam artikelmemenuhi persyaratan dan digunakan untuk review ini.Hasil: Dari keenam penelitian menunjukkan bahwa semakintinggi asupan air, semakin baik hidrasi atau asupan airmeningkatkan berat bayi lahir. Semua penelitian mengukurkonsumsi air atau status hidrasi antara 8-37 minggu. Studistudiini secara konsisten memberikan bukti bahwa asupanair yang rendah atau kondisi kekurangan cairan dikaitkandengan berat badan lahir rendah, terlepas dari durasi studi.Kesimpulan: Kajian ini menunjukkan bahwa peningkatanasupan air ibu hamil berpengaruh positif terhadap beratlahir bayi. Asupan air yang cukup pada ibu hamil adalah2180 – 3000 mL setiap hari bergantung pada status hidrasidan usia kehamilan.Kata kunci: asupan air, berat lahir, hidrasi, kehamilan
Diagnostic Performance of Urine-based HPV-DNA Test (CerviScan, Bio Farma) as Cervical Cancer Screening Tool in Adult Women: Performa Tes Diagnostik DNA-HPV berbasis Urine (CerviScan, Bio Farma) sebagai Alat Skrining Kanker Serviks pada Perempuan Dewasa
No full textObjective: Detection of high-risk human papillomavirus (hr-HPV) in urine specimens has been introduced recently and a new local PCR kit has been developed in Indonesia (CerviScan, Bio Farma). The objective of this study was to obtain the accuracy of hr-HPV DNA testing using the new kit (CerviScan, Bio Farma) on urine specimens against the gold standard on cervical swabs.Method: Adult women (aged 20–50 years) underwent routine general check-up or Pap test were enrolled between July and September 2022. Pairs of urine and cervical swab specimens were obtained from all subjects. HPV-DNA tests were performed using the new local PCR kit (CerviScan, Bio Farma) and the standard procedure (COBAS® 6800 HPV, Roche Molecular System). Direct sequencing was added whenever there were dispute results between the two methods. Agreement between both methods was tested using Kappa statistics. Diagnostic performance test was done on CerviScan. Results: A total of 876 women completed the examination. Agreement between CerviScan and COBAS® 6800 was substantial (K=0.662; p<0.001) and was almost perfect against COBAS® 6800 plus sequencing (K=0.828; p<0.001). The accuracy of CerviScan on urine samples was 95.8% against COBAS® 6800 and increased to 97.8% after additional sequencing. The sensitivity and specificity of CerviScan on urine samples compared to cervical swabs are 73.1% and 97.3%, respectively.Conclusion: Urine-based HPV-DNA testing with CerviScan is a reliable tool to detect high-risk HPV subtypes. It could become an alternative method for HPV-DNA testing to improve the coverage of cervical cancer screening program
Infertile Couple and Pregnancy Outcomes for Patients Undergoing a Pregnancy Program in the Rural Area of Nagekeo District, Flores, East Nusa Tenggara : Pasangan Infertil dan Luaran Kehamilan pada Pasien yang Menjalani Program Kehamilan di Kabupaten Nagekeo, Flores, Nusa Tenggara Timur
No full textObjective: To elucidate the characteristics of infertile couples residing in the rural area of Nagekeo Regency and assess the outcomes of their participation in the local pregnancy program.
Methods: We conducted a descriptive study at Aeramo Regional General Hospital (RGH) in Nagekeo Regency, Flores, East Nusa Tenggara (ENT), utilizing a total sampling technique from January 2020 to April 2022. A total of 56 couples participated in this study.
Results: The analysis revealed that infertile couples at Aeramo RGH were typically aged between 23 and 35 years, with an average infertility duration exceeding 4 years. Primary infertility was the predominant condition (89.3%), with 55.4% of male partners exhibiting obesity. A significant number of male participants reported alcohol and cigarette consumption. Data were insufficient to determine the prevalence of infertility in men versus women. Notably, the outcomes of the pregnancy program in this region did not demonstrate significant improvements.
Conclusions: This study identified potential risk factors such as smoking, alcohol consumption, and obesity that may contribute to infertility; however, it did not establish a strong correlation between these factors and infertility. Moreover, the pregnancy program's outcomes were inconclusive, likely due to limited diagnostic and treatment resources in the area.
Keyword: infertility characteristics, pregnancy program, pregnancy outcomes.
Abstrak
Tujuan : Mendeskripsikan karakteristik pasangan infertil di Kabupaten Nagekeo serta mengetahui hasil luaran kehamilan bagi pasangan yang mengikuti program kehamilan di daerah tersebut.
Metode : Penelitian ini merupakan penelitian deskriptif yang dilakukan di Rumah Sakit Umum Daerah (RSUD) Aeramo, Kabupaten Nagekeo, Flores, Nusa Tenggara Timur. Dengan menggunakan teknik total sampling pada periode Januari 2020 - April 2022, terdapat 56 pasangan yang bergabung dalam penelitian ini.
Hasil : Hasil penelitian kemudian dianalisis secara univariat dan didapatkan usia pasangan infertil di Aeramo RGH adalah antara 23 - 35 tahun dengan durasi infertilitas lebih dari 4 tahun. Infertilitas primer dan obesitas pada pria mendominasi masing-masing kelompok yaitu 89,3% dan 55,4%. Mayoritas pria mengonsumsi alkohol dan rokok. Tidak ditemukan data yang cukup untuk menentukan apakah infertilitas terjadi pada pria atau wanita. Hasil dari program kehamilan yang dilakukan di daerah ini belum menunjukkan hasil yang signifikan.
Kesimpulan : Karakteristik yang memicu faktor risiko seperti merokok, mengkonsumsi alkohol dan obesitas. Meskipun pada penelitian ini belum didapatkan korelasi yang kuat dari faktor risiko tersebut pada infertilitas. Hasil dari program kehamilan belum menunjukkan hasil yang signifikan karena modalitas diagnostik dan pengobatan yang sangat terbatas.
Kata kunci : karakteristik infertilitas, luaran kehamilan, program hamil
Optimal Omega-3 Intake: A Natural Way to Ease Primary Dysmenorrhea Severity: Asupan Omega-3 yang Optimal: Cara Alami untuk Mengurangi Derajat Dismenore Primer
No full textMenstrual Cycle Length and Dysmenorrhea in Female Adolescents Aged 9-18 Years
Full text linkAbstract
Objective: To determine the relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta.
Methods: This study used a cross-sectional study approach to conduct observational analytic research. The study samples were female students aged 9-18 years in Sang Timur Tomang School. Study data were obtained through the Verbal Multidimensional Scoring System (VMSS) questionnaire in Indonesian. The Chi-square test of independence was used to determine the relationship between menstrual cycle length and dysmenorrhea.
Results: From a total of 137 respondents, 38% have abnormal menstrual cycle length. Eighty-two-point-seven percent of respondents who have abnormal menstrual cycle length experienced dysmenorrhea, and 17,3% of participants who have abnormal menstrual cycle length did not experience dysmenorrhea. Chi-square test results showed a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta (p = 0,005).
Conclusion: There is a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta.
Keywords: female adolescents, dysmenorrhea, menstrual cycle, menstrual cycle lengt